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compositionComposition:IRON-50MG
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Orofer Syrup is used to treat iron deficiency anaemia. It contains Iron, which aids the formation of red blood cells to carry oxygen to other body cells and tissues. In some cases, this medicine may cause side effects such as constipation, diarrhoea, stomach cramps, dark stools, loss of appetite, and upset stomach. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

IRON-50MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Orofer Syrup

Orofer Syrup is primarily taken to treat or prevent low levels of red blood cells in the blood, a condition often associated with fatigue and weakness. It serves a vital medical purpose by helping your body produce haemoglobin, the essential protein that carries oxygen from your lungs to the rest of your organs and tissues.

To achieve the best results, this medicine is typically taken daily or as directed by your healthcare provider, and consistency is key to restoring your body's natural reserves. For optimal absorption, it is best to take it on an empty stomach, though you can take it with food if it causes stomach irritation. Incorporating simple dietary adjustments, such as eating foods high in Vitamin C, can also significantly help your body absorb this medicine more efficiently.

While taking Orofer Syrup , some people may experience mild, manageable side effects like dark stools or mild constipation. However, you should consult your doctor immediately if you experience severe symptoms, such as sharp stomach pain, chest pain, or signs of an allergic reaction.

Before starting this medicine, you must talk to your doctor if you have specific pre-existing health conditions. Do not take this if you have conditions associated with excess mineral build-up, have had frequent blood transfusions, or suffer from severe stomach ulcers.

Additionally, Orofer Syrup can interact with certain substances; for instance, taking it alongside antacids or specific antibiotics can stop it from working properly. If you are pregnant, breastfeeding, planning a pregnancy, or are an older adult, consult your doctor to ensure you are taking the safest and most appropriate dose for your needs.

Uses of Orofer Syrup

Orofer Syrup is used to treat or prevent low levels of red blood cells in the blood. The detailed uses of Orofer Syrup are as follows:

  • Anaemia caused by low mineral levels: Orofer Syrup helps by replenishing the body's natural stores of this essential nutrient, which is required to build healthy red blood cells and restore overall energy.
  • Red blood cell support during pregnancy: Orofer Syrup helps meet the increased demand for blood volume and oxygen transport, supporting both maternal health and fetal development.
  • Dietary deficiency: Orofer Syrup helps restore normal blood levels in individuals who do not get a sufficient amount of this key nutrient from their daily diet alone.

Key Benefits

Orofer Syrup helps restore healthy red blood cell levels, improving oxygen delivery throughout the body and supporting overall health. With regular use, it helps boost energy, enhances mental performance, and promotes healthier skin, hair, and nails.

  • Boosts Energy and Reduces Fatigue: By helping your body produce more red blood cells, this medicine improves oxygen flow to tissues, reducing tiredness and helping you feel more active, alert, and physically capable.
  • Improves Focus and Mental Clarity: Better oxygen delivery to the brain helps reduce cognitive fog, supporting improved concentration, memory, and overall productivity.
  • Supports Healthy Skin, Hair, and Nails: By restoring essential nutrient levels needed for healthy red blood cell production, this medicine helps improve pale skin, brittle nails, and hair thinning associated with depleted red blood cell counts.

Directions for Use

  • Orofer Syrup can be taken with or without food, as advised by the physician.
  • Take Orofer Syrup at the same time each day to maintain consistency and get the best results.
  • Swallow Orofer Syrup as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Orofer Syrup Works

Orofer Syrup contains iron, which works by supplying the key building block that your body needs to manufacture haemoglobin. Haemoglobin is the protein inside your red blood cells that binds to oxygen in your lungs and carries it to your tissues and organs. When your body does not have enough of this key nutrient, it cannot produce sufficient haemoglobin, leading to oxygen deprivation in the tissues, which causes fatigue and weakness. When you take Orofer Syrup , it is absorbed through your digestive tract and directly utilised by your bone marrow to create new, healthy red blood cells. Over time, this process replenishes your body's internal storage depots, restoring normal oxygen distribution, enhancing physical stamina, and reversing the symptoms associated with depleted blood levels.
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Alcohol

Caution

It is advised to avoid alcohol intake while using Orofer Syrup since alcohol can hinder the absorption of iron in Orofer Syrup .

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Pregnancy

Consult your doctor

Orofer Syrup is safe to use if advised by a doctor during pregnancy. Orofer Syrup is generally given at least four weeks before pregnancy and is continued up to 3 months of pregnancy.

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Breast Feeding

Caution

Orofer Syrup can pass into the breast milk when used by a breastfeeding mother. Please consult your doctor before taking Orofer Syrup if you are a nursing mother

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Driving

Safe

Orofer Syrup does not affect your ability to drive or operate any machinery. If you notice any side effects that affect your mental ability while using Orofer Syrup , please consult your doctor.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Orofer Syrup .

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Kidney

Caution

It is advised to seek doctor advice before starting Orofer Syrup if you have kidney diseases.

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Children

Consult your doctor

The doctor will decide the dosage of Orofer Syrup based on the child's age and weight.

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Heart

Consult your doctor

Consult your doctor if you have a history of heart disease. Your doctor will recommend only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Orofer Syrup should be given to elderly patients only if recommended by a doctor. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Orofer Syrup

In case of an accidental overdose, seek emergency medical attention immediately. An overdose of this mineral can be highly toxic, especially to young children, and requires urgent medical intervention.

Diet & Lifestyle Advise

  • Eat foods rich in Vitamin C, such as oranges, strawberries, bell peppers, and broccoli, alongside your dose to help your body absorb Orofer Syrup more effectively.
  • Avoid consuming dairy products, eggs, tea, coffee, or high-fibre foods within two hours of taking your medication, as these can block its absorption.
  • Drink plenty of water and maintain a fibre-rich diet to help prevent or ease the constipation that frequently occurs with this supplement.
  • Incorporate naturally nutrient-rich foods into your diet, including lean meats, poultry, beans, lentils, and dark leafy green vegetables, to support healthy blood production.

Health Queries

What is the correct daily dose in milliliters (ml) of Orofer syrup (30mg in 5ml) for my 4-year-old son who weighs 16.5 kg and has a low hemoglobin (blood) level of 9.2, since I have lost his prescription?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

For a child weighing 16.5 kg, a typical daily dose of Orofer (iron) syrup is usually around 5 ml to 8 ml (30 to 48 mg of elemental iron) daily, often given with food to prevent stomach upset. However, because exact dosing for iron must be highly precise to avoid toxicity, it is crucial to consult his pediatrician or pharmacist to confirm his specific prescribed dose before administering it. They can easily print a new copy for you!

What should I do if I am feeling weak again and my legs give out after walking just a short distance, even though I have been taking Orofer syrup for a low hemoglobin level of 8.6 that was found on my blood test last month?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Orofer (iron) syrup takes several weeks to fully rebuild your hemoglobin levels and restore your strength. However, because your legs are giving out, it is very important to contact your doctor promptly. They will likely want to repeat your blood test to see if your hemoglobin is rising and ensure there are no other reasons for your weakness. For now, please avoid overexerting yourself, stand up slowly, and rest as much as possible.
health query

Have a query?

How Soon It Starts Working

  • The time required for Orofer Syrup to start to work: The time required for Orofer Syrup to show its action is unknown.
  • The time for which the effects of Orofer Syrup last: The duration of action for Orofer Syrup is clinically unknown.

Storage

• Store Orofer Syrup at a controlled room temperature, strictly between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original container, tightly closed, and stored in a dry place away from direct sunlight and moisture.

What if you forget to take Orofer Syrup

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular schedule. Do not take a double dose to make up for a missed one.

Drug Warnings

  • Always check the product packaging before use to ensure the tablets or liquid have not changed in appearance, colour, or consistency.
  • If you are taking a liquid form of Orofer Syrup , mix it with water or juice and drink it through a straw to prevent the liquid from temporarily staining your teeth.
  • Do not take antacids, calcium supplements, or daily multivitamins within two hours of taking Orofer Syrup , as they can significantly lower its effectiveness.
  • Inform any healthcare professional treating you, including dentists, that you are taking Orofer Syrup , as it can occasionally interfere with certain medical tests.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain Antibiotics and Thyroid Medicines: Orofer Syrup may reduce the absorption and effectiveness of certain antibiotics, such as tetracyclines and fluoroquinolones, as well as thyroid medicines like levothyroxine. To minimise this interaction, take these medicines at least 2 hours before or after taking Orofer Syrup .
    Acid-Reducing Medicines: Antacids, H2 blockers, and proton pump inhibitors can reduce the absorption of the active mineral in Orofer Syrup , making it less effective. Your doctor may advise adjusting the timing of these medicines or recommend an alternative treatment.
     
Ferrous sulfateDolutegravir
Severe
Ferrous sulfateMycophenolic acid
Severe

Drug-Drug Interactions

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Ferrous sulfateDolutegravir
Severe
How does the drug interact with Orofer Syrup 300 ml:
Taking dolutegravir with Orofer Syrup 300 ml can reduce the effectiveness of dolutegravir.

How to manage the interaction:
Although there is a possible interaction between Orofer Syrup 300 ml and Dolutegravir, you can use these medicines together if prescribed by a doctor. It is advised to take dolutegravir either two hours before or six hours after taking a dose of Orofer Syrup 300 ml. Do not discontinue using any medications without consulting a doctor.
Ferrous sulfateMycophenolic acid
Severe
How does the drug interact with Orofer Syrup 300 ml:
Co-administration of Orofer Syrup 300 ml with Mycophenolic acid decreases levels of Mycophenolate by reducing its absorption.

How to manage the interaction:
There could be a possible interaction between Mycophenolic acid and Orofer Syrup 300 ml, but they can be taken together if a doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath consult a doctor. Do not discontinue any medications without a doctor's advice.
Ferrous sulfateDimercaprol
Severe
How does the drug interact with Orofer Syrup 300 ml:
Co-administration of Dimercaprol can make Orofer Syrup 300 ml, which may increase the risk of toxicity of the kidneys.

How to manage the interaction:
Co-administration of Orofer Syrup 300 ml with Dimercaprol can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Dairy Products, Eggs, Tea, Coffee, and Whole Grains: These foods and beverages contain compounds that can bind to the active mineral in Orofer Syrup and reduce its absorption. To help your body absorb the medicine properly, avoid consuming them at the same time as your dose.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NUTRITIONAL SUPPLEMENT]

FAQs

Orofer Syrup belongs to a class of haematinics; primarily used to treat iron deficiency and anaemia (deficiency of iron and haemoglobin).
Orofer Syrup is a dietary supplement that contains Iron. It works by boosting the production of red blood cells (RBC) in the body, thus treating iron deficiency-associated anaemia.
It is recommended not to take Orofer Syrup along with tea, coffee, or milk, and eggs since they might interfere with iron absorption from Orofer Syrup .
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage. Do not double the dose.
Iron is best absorbed if taken on an empty stomach. However, in some patients, Orofer Syrup may cause gastrointestinal disturbances, such as stomach upset, when taken without food. So, please take it as suggested by your doctor if you have stomach problems.
Orofer Syrup may cause constipation as one of its side effects. Eating fibre-rich foods like vegetables, fresh fruits, and cereals, and drinking plenty of water can help relieve symptoms.
Antacids may interfere with the absorption of iron. Hence, it is advised to take Orofer Syrup two hours before, or four hours after taking antacids.
No, you should avoid taking Orofer Syrup with coffee or tea. These beverages contain compounds that can significantly reduce how much of the medicine your body absorbs. It is best to wait at least two hours after taking your medicine before enjoying these drinks. Talk to your doctor or pharmacist if you need help planning your daily routine.
Having dark or black-colored stools is a very common and completely harmless occurrence. It simply means your body is naturally eliminating the portion of the mineral that it did not absorb. However, if your stools are sticky, tarry, or accompanied by severe stomach pain, talk to your doctor immediately.
Yes, Orofer Syrup is very commonly suggested during pregnancy to support the increased blood supply needed for both the mother and baby. However, you should only take the specific dose recommended by your healthcare provider. Talk to your doctor to determine the appropriate amount for your pregnancy.
No, you should swallow the tablets whole. Crushing, chewing, or breaking them can cause too much of the medicine to be released at once, which increases the risk of stomach irritation and can stop it from absorbing properly. If you find it hard to swallow tablets, talk to your doctor or pharmacist about switching to a liquid form.
Constipation is a common side effect of this medication. You can manage it by increasing your daily water intake and eating more high-fibre foods. If the issue persists or becomes severe, talk to your doctor or pharmacist before taking any laxatives.
It is generally best to separate them. Many multivitamins contain calcium or other minerals that can compete with Orofer Syrup , making it less effective. Try to space them at least two hours apart, and talk to your doctor or pharmacist to help organise your supplement schedule.
No, there is no clinical evidence to suggest that taking Orofer Syrup directly causes weight gain. If you notice any unexpected changes in your weight while taking this medication, talk to your doctor to identify the underlying cause.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Ferrous Sulfate Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Iron dextran injection [Prescribing Information]. 2021. [Accessed on 10 Jun. 2025]Check here
  4. Iron Sucrose Injection [Summary of Product Characteristics]. 2024. [Accessed on 10 Jun. 2025]Check here
  5. Venofer (iron sucrose) 20 mg iron / ml, solution for injection or concentrate for solution for infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 31 Oct 2025]Check here
  6. Venofer (iron sucrose) 20 mg iron / ml, solution for injection or concentrate for solution for infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 31 Oct 2025]Check here
  7. Drugs H. Iron Sucrose Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2022 [Accessed on 31 Oct 2025]Check here

Country of origin

INDIA

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - ORO0122

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