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Oxamil Syrup 450 ml is a combination medicine used in the treatment of Kidney stones and renal tubular acidosis. This medicine works by increasing the urinary pH, potassium, magnesium, and citric acid levels, thereby preventing the crystallisation, growth, and accumulation of stone-forming salts. It helps alleviate a burning sensation during urination. Common side effects include abdominal discomfort, diarrhoea, nausea, and vomiting.
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About Oxamil Syrup 450 ml
Oxamil Syrup 450 ml is indicated for the treatment of renal tubular acidosis and kidney stones. It also helps alleviate burning sensations during urination. Kidney stones are small, hard deposits made up of calcium, phosphate and other minerals/acid salts that stick together in concentrated urine. Renal tubular acidosis is a condition in which the kidneys fail to excrete acids into the urine, which causes the blood to remain too acidic.
Oxamil Syrup 450 ml is a combination of three drugs, namely: Magnesium citrate, Potassium citrate, and Pyridoxine. Oxamil Syrup 450 ml raises the urinary pH, potassium, magnesium, and citric acid levels, which prevents the crystallisation, growth, and accumulation of stone-forming salts.
You are advised to take Oxamil Syrup 450 ml for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as abdominal discomfort, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Before taking the Oxamil Syrup 450 ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Oxamil Syrup 450 ml is not recommended for children as safety and effectiveness have not been established.
Uses of Oxamil Syrup 450 ml
Oxamil Syrup 450 ml is a combination medication containing magnesium citrate, potassium citrate, and pyridoxine (vitamin B6). It is primarily used to manage and prevent certain kidney-related conditions. The detailed uses of Oxamil Syrup 450 ml are as follows:

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Directions for Use
Medicinal Benefits
Oxamil Syrup 450 ml is a combination of three drugs, namely: Magnesium citrate, Potassium citrate, and Pyridoxine. Oxamil Syrup 450 ml is indicated for the treatment of renal tubular acidosis, kidney stones. It prevents the recurrence of calcium oxalate nephrolithiasis (calcium oxalate stones) and uric acid lithiasis (uric acid stones) with or without calcium stones. It also helps alleviate burning sensations during urination. Oxamil Syrup 450 ml raises the urinary pH, potassium, magnesium, and citric acid levels, which prevents the crystallisation, growth, and accumulation of stone-forming salts.
How Oxamil Syrup 450 ml Works
Storage
What if I have taken an overdose of Oxamil Syrup 450 ml
Drug Warnings
Before taking Oxamil Syrup 450 ml, inform your doctor about all your medical conditions, allergies, and any medications you are currently using. Also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding. Oxamil Syrup 450 ml is not recommended for children, as its safety and effectiveness have not been established. It is not known whether it is safe to consume alcohol with Oxamil Syrup 450 ml, so it is best to avoid or limit alcohol use as a precaution. To manage your condition effectively, use Oxamil Syrup 450 ml exactly as prescribed and for the full duration recommended by your doctor. Do not take more than the prescribed dose or use it for longer than advised, as this may lead to adverse effects.
Diet & Lifestyle Advise
Habit Forming
Therapeutic Class

by Others
by Others
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by Others
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Alcohol
Caution
It is not known whether it is safe to consume alcohol with Oxamil Syrup 450 ml, so it is best to avoid or limit alcohol use as a precaution.
Pregnancy
Caution
Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Caution
Consult your doctor if you are breastfeeding; your doctor will decide whether breastfeeding mothers can take Oxamil Syrup 450 ml or not.
Driving
Safe if prescribed
Oxamil Syrup 450 ml is unlikely to affect your ability to drive. However, you are advised to drive only if you are alert.
Liver
Caution
Limited information is available regarding the usage of Oxamil Syrup 450 ml in patients with hepatic impairment. Please consult your doctor if you have liver problems or any concerns regarding this.
Kidney
Unsafe
Oxamil Syrup 450 ml might cause soft tissue calcification and hyperkalaemia in patients with renal insufficiency. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Unsafe
The safety and effectiveness of Oxamil Syrup 450 ml in children have not been established.
Oxamil Syrup 450 ml is used to treat kidney stones and renal tubular acidosis (accumulation of acid in the body due to the failure of the kidneys to acidify the urine).
Oxamil Syrup 450 ml raises the urinary pH, potassium, magnesium and citric acid levels; this prevents the crystallisation of stone-forming salts.
Avoid taking Oxamil Syrup 450 ml if you have peptic ulcers, as Oxamil Syrup 450 ml has ulcerogenic potential, which could lead to further ulceration.
Diarrhoea might be a side-effect of Oxamil Syrup 450 ml. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Consult a doctor before taking Oxamil Syrup 450 ml if you have an active urinary tract infection, as Oxamil Syrup 450 ml increases the urinary pH, which might promote further bacterial growth.
Do not discontinue Oxamil Syrup 450 ml without consulting your doctor. To treat your condition effectually, continue taking Oxamil Syrup 450 ml for as long as prescribed. Do not hesitate to consult your doctor if you experience any difficulties while taking Oxamil Syrup 450 ml.
Oxamil Syrup 450 ml may cause common side effects such as abdominal discomfort, diarrhoea, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Oxamil Syrup 450 ml should be used during pregnancy only if prescribed by the doctor. Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
Drink enough water to avoid dehydration. Include fruits and vegetables in your diet. Eat more calcium-rich foods, such as leafy green vegetables, dairy products, salmon, and sardines, and avoid stone-forming foods like spinach, rhubarb, tea, beets, and chocolate.
Do not take Oxamil Syrup 450 ml if you are allergic to any of its contents; if you have hyperkalaemia (high levels of potassium), chronic renal failure, uncontrolled diabetes mellitus, adrenal insufficiency, acute dehydration, oesophageal compression, delayed gastric emptying, intestinal obstruction, peptic ulcers, urinary tract infection, or renal insufficiency.
No interactions between Oxamil Syrup 450 ml and food have been established. However, to prevent kidney stones, you are advised to avoid foods rich in oxalates, such as spinach, nuts, dates, avocado, hot chocolate, cocoa, baked potato, French fries, and cereals. Also, avoid potassium-rich foods like bananas, apricots, almonds, beans, and potatoes.
Before starting Oxamil Syrup 450 ml, inform the doctor if you have any other health conditions, such as hyperkalaemia or gastrointestinal lesions, or if you are taking any other medications.
Consult your doctor before taking Oxamil Syrup 450 ml with other medications, such as potassium-sparing diuretics, painkillers, or antihypertensives.
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