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compositionComposition:DINOPROSTONE-0.5MG
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Prescription Medicine
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Primigyn Gel 3 gm is used to prepare the cervix for the initiation of labour in pregnant women. It contains Dinoprostone, which stimulates uterine muscles and increases the contractions of the uterus. This medicine may sometimes cause side effects such as back pain, vomiting, diarrhoea, flushing of the skin, and foetal distress. Inform the doctor if you are taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DINOPROSTONE-0.5MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Vaginal

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Primigyn Gel 3 gm

Primigyn Gel 3 gm is a specialized vaginal medication used to prepare and soften the cervix (the neck of the womb) for labour induction in pregnant women. It is prescribed when childbirth needs to be started medically at or near the delivery date. This preparation makes it easier for the cervix to open, helping to facilitate a smoother delivery process.

Unlike routine medications, this treatment is typically given as a single application by a healthcare professional in a hospital setting. Because it is inserted vaginally, food does not affect how it works, and no routine dietary changes are necessary before its use. Staying well-hydrated and resting comfortably are the best ways to support the process during its application.

Some women may experience mild stomach cramping, a warm sensation in the vagina, or mild nausea after insertion. However, you must inform your healthcare provider immediately if you experience severe abdominal pain, unusually strong or frequent contractions, or vaginal bleeding. These serious reactions require prompt medical attention to ensure both your and your baby's safety.

Do not take this if you have had a cesarean section or major uterine surgery in the past, or if you have been told your baby is in an unusual position for birth. Before receiving Primigyn Gel 3 gm, tell your doctor if you have a history of asthma, glaucoma, high blood pressure, liver damage, or kidney disease. This helps your medical team assess if this is the safest option for your delivery.

Primigyn Gel 3 gm can interact with other labour-inducing drugs, which is why they should not be used at the same time. Since it is designed specifically to start labour, its use is strictly limited to late-stage pregnancy under medical supervision, and it is not intended for breastfeeding or elderly individuals. Talk to your doctor or pharmacist if you have questions about how other substances might affect this treatment.

Uses of Primigyn Gel 3 gm

Primigyn Gel 3 gm is used in the management of Labour induction. The detailed uses of Primigyn Gel 3 gm are as follows:

  • Labour induction: It is used to kickstart the labour process when medical reasons require the delivery to begin before it starts naturally.
  • Cervical ripening: Primigyn Gel 3 gm helps soften, thin, and dilate the cervix in pregnant women who are at term, making the body ready for childbirth.

Key Benefits

Primigyn Gel 3 gm helps prepare the cervix for labour and supports the induction of childbirth when medically indicated. By promoting cervical ripening and helping labour progress, it supports a safer and more effective delivery process under medical supervision.
Benefits may include:

  • Helps soften and prepare the cervix for labour.
  • Supports the induction of labour when recommended by your doctor.
  • Promotes more effective progression of labour.
  • May help reduce the duration of labour in appropriate patients.
  • Increases the likelihood of a successful vaginal delivery when used as indicated.
  • Supports safe labour management under close medical supervision.
     

Directions for Use

  • Primigyn Gel 3 gm is for vaginal use only.
  • It is not intended for self-application, as it is administered by a healthcare professional in a hospital setting at the appropriate time to help your cervix for labour.
  • Primigyn Gel 3 gm is applied directly to the cervix through the vagina using a specialized applicator. This is typically done while you are lying on your back.
  • After the application, you will need to remain lying down for 15 to 30 minutes, and possibly up to 2 hours, unless your doctor gives different instructions.

How Primigyn Gel 3 gm Works

Primigyn Gel 3 gm works by acting like the natural substances, called prostaglandins, that your body produces when it is ready to go into labour. When inserted into the vagina, it targets the tissues of the cervix directly. It helps break down the tough fibres in the cervix, causing it to soften, thin out, and begin to open. In addition to softening the cervix, this medication gently signals the muscles of the uterus to start contracting. These contractions help push the baby downward, further encouraging the cervix to dilate and helping your labour progress safely and naturally.
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Alcohol

Unsafe

No interactions were established.

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Pregnancy

Safe if prescribed

Primigyn Gel 3 gm is used to induce uterine contractions at delivery time. It is not for self-application purposes as usually applied in hospital settings under the supervision of medical healthcare professionals.

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Breast Feeding

Caution

Primigyn Gel 3 gm is most likely unsafe to use while breastfeeding. Based on limited human data, the drug may pass into breast milk and harm your infant.

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Driving

Unsafe

No interactions were established.

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Liver

Caution

Inform your doctor if you have liver problems before taking Primigyn Gel 3 gm. Your doctor will weigh the benefits and the risks before prescribing this medicine.

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Kidney

Caution

Primigyn Gel 3 gm can cause fluid retention if used in patients with kidney disease. Hence, inform your doctor if you have kidney problems before taking Primigyn Gel 3 gm. Your doctor will weigh the benefits and the risks before prescribing this medicine.

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Children

Unsafe

Primigyn Gel 3 gm is not recommended for children below the age of 18 years. The safety and effectiveness of Primigyn Gel 3 gm have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Primigyn Gel 3 gm. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Primigyn Gel 3 gm in elderly patients. Please consult your doctor.

What if I have taken an overdose of Primigyn Gel 3 gm

Because Primigyn Gel 3 gm is carefully measured and monitored by medical experts in a clinic, an overdose is highly unlikely. If your body reacts too strongly to the medicine, or if contractions become too intense, the medical team can immediately remove the insert or provide treatment to slow down the contractions.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of water or clear fluids before your procedure, as staying hydrated helps support normal muscle function during contractions.
  • Eat light meals: Choose light, easily digestible meals before your hospital admission to help reduce the risk of nausea or stomach discomfort.
  • Practice breathing exercises: Use deep, rhythmic breathing techniques to help you stay relaxed and manage early cramps as the medicine begins to take effect.
  • Maintain a comfortable resting position: Keep a comfortable, supportive position while resting in bed during the recommended lying-down period after the medicine has been inserted.

Health Queries

I am 11 days past my delivery due date; is this normal, and do I need to take any medication to induce labor?

Veda Maddala

Veda Maddala

M Pharmacy

Being 11 days past your due date is relatively common, but it is considered a post-term pregnancy. At this stage, it is highly recommended to contact your obstetrician immediately. Your doctor will perform tests to check your baby's well-being and amniotic fluid levels. To ensure a safe delivery, medical induction is usually recommended by 42 weeks. This is safely managed in a hospital using medications like prostaglandins to soften the cervix or an intravenous drip of oxytocin (Pitocin) to stimulate contractions. Please do not attempt to self-induce with unprescribed medications or herbs; contact your healthcare provider right away to plan your delivery.
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Have a query?

How Soon It Starts Working

The time required for Primigyn Gel 3 gm to start to work: Primigyn Gel 3 gm ideally shows its action within 10 minutes after insertion. The time for which the effects of Primigyn Gel 3 gm last: The effect of Primigyn Gel 3 gm lasts for 2 to 6 hours.

What if you forget to take Primigyn Gel 3 gm

Since this medication is inserted in a hospital setting by a healthcare professional as a single-use procedure, a missed dose is not possible. If the treatment needs to be repeated or adjusted, your clinical team will handle it directly.

Storage

• it must be kept frozen between -20°C and -10°C (-4°F to 14°F) or refrigerated between 2°C and 8°C (36°F to 46°F). •It must be kept in its original, moisture-resistant packaging until the moment it is ready to be used.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Do not insert or adjust the medicine yourself: Primigyn Gel 3 gm should only be inserted, removed, or adjusted by a qualified healthcare professional.
  • Do not pull or adjust the retrieval string: If a vaginal insert with a retrieval string is used, do not pull, tug, or adjust the string, as this may displace the medicine.
  • Expect close monitoring during treatment: Your baby's heart rate and your uterine contractions will be monitored regularly or continuously throughout treatment.
  • Report changes immediately: Inform your doctor or nurse right away if your water breaks or you experience a sudden gush or leakage of fluid.
  • Follow positioning instructions: Remain lying down for the length of time recommended by your healthcare team to help keep the medication in place and ensure it works effectively.

Drug-Drug Interactions

verifiedApollotooltip
  • Other labor-inducing medicines (e.g., oxytocin): Taking these medicines alongside Primigyn Gel 3 gm may cause excessively strong or frequent uterine contractions. Your doctor will carefully monitor and time these treatments if both are needed.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Primigyn Gel 3 gm when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

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FAQs

Primigyn Gel 3 gm is used for the initiation or improvement of uterine contraction (antepartum) and producing uterine contraction during the third stage of labour (postpartum).
Primigyn Gel 3 gm contains a prostaglandin Dinoprostene that works by increasing the production of a natural substance called prostaglandins (PGs), which softens and widens the cervix (opening of the womb) and increases uterus contractions. As a result, these increased uterine contractions and widened cervix help deliver the child.
Primigyn Gel 3 gm is given as a suppository or a gel applied at a hospital only under strict medical supervision. The dose to be administered will be decided by your doctor, depending on your current medical situation.
The most common side effects of Primigyn Gel 3 gm include vomiting, back pain, diarrhoea, flushing of the skin, and fetal distress. You might also feel increased uterine contractions for some time, but these are manageable under medical supervision.
If you have a previous premature delivery or a c-section, or cervical surgery, please inform your doctor before starting Primigyn Gel 3 gm. Also, mention a detailed medical history to your doctor to avoid complications.
No, Primigyn Gel 3 gm should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects like fetal distress or delivery complications.
It is advised to use Primigyn Gel 3 gm only if prescribed by a doctor as there are chances of increased complications in women aged 35 and above and if you smoke.
For some women, contractions may begin within a few hours of insertion, while for others, it gently prepares the cervix over a longer period before labour starts. Talk to your doctor.
The insertion process is similar to a standard pelvic exam and may cause brief discomfort, but it is generally not painful. Talk to your doctor or pharmacist.
If the insert slips out, tell your nurse or doctor immediately so they can check your progress and replace it if necessary. Talk to your doctor.
The vaginal insert version has a retrieval string that allows your healthcare provider to pull it out quickly if your contractions become too intense. Talk to your doctor.
Your clinical team will use external monitors placed on your abdomen to track your baby’s heart rate and the frequency of your contractions. Talk to your doctor or pharmacist.
If your cervix does not ripen or labour does not progress, your medical team will evaluate your situation and discuss alternative options, such as other medications or a cesarean delivery. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Other Info - PRI0167
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