| Information for
patients
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| Drug Information |
•Misoprostol contain misoprostol which is similar to a chemical substance called ''''prostaglandin'''' which your body produces naturally. Prostaglandins are produced in the stomach and intestine and help to protect the lining. Misoprostol belongs to a group of medicines known as ''''anti-ulcer agents''''.
•The Misoprostol may help prevent you getting ulcers in your stomach or the part it empties into, called the duodenum. These ulcers could be caused by taking non-steroidal anti inflammatory drugs (NSAIDs) like diclofenac and naproxen. The way NSAIDs work means they reduce the amount of prostaglandins in your stomach and intestine. This can cause indigestion and lead to ulcers forming. The Misoprostol will replace these prostaglandins and help to protect your stomach and intestine, so you can continue getting benefit from your NSAID. Misoprostol also reduces acid and increases bicarbonate in your stomach secretions.
•Misoprostol can also be used to heal existing ulcers. |
| Drug Alert |
| Alert |
•are pregnant or trying to become pregnant because it may cause a miscarriage (see Section
•are breastfeeding.
•have ever had an allergic reaction to Misoprostol or any of the other ingredients in it, or other prostaglandin medicines in the past. |
| Before Consuming
the Medicine
|
| Avoid Drug |
•are pregnant or trying to become pregnant because it may cause a miscarriage (see Section
•are breastfeeding.
•have ever had an allergic reaction to Misoprostol or any of the other ingredients in it, or other prostaglandin medicines in the past. |
| Drug Special Care |
•low or high blood pressure, or any disease of the blood vessels
•Inflammatory bowel disease
If you are a younger woman who has not yet gone through the menopause, your doctor will have only prescribed Misoprostol if he is satisfied you are at high risk of developing ulcers from your NSAID medicine |
| Drug Drug Interactions |
You can take Misoprostol with most medicines without any problems. If you use an antacid (something to reduce acid in the stomach) you should avoid antacids with magnesium in them as these may make diarrhoea worse.If you are taking any medicines for a heart condition, please consult your doctor.Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription |
| Drug Pregnancy Interaction |
If you are a younger woman who has not yet gone through the menopause, your doctor will have only prescribed Misoprostol if he is satisfied you are at high risk of developing ulcers from your NSAID medicine. Your doctor will make you aware of the risks if you do become pregnant.Misoprostol can cause a miscarriage so it’s very important to use reliable contraception while taking this medicine. If you want to try for a baby, tell your doctor as you will have to stop taking Misoprostol and use a different treatment.Misoprostol should not be taken by pregnant women and in women planning a pregnancy |
| Drug Breast feeding Interaction |
Do not breastfeed while taking Misoprostol |
| Drug Machinery Interaction |
Dizziness has been reported after taking Misoprostol. Be cautious when driving or operating machinery until you know how the medicine affects you. |
| Drug More Information |
You should take your Misoprostol tablet with food |
| How to take the
Medicine
|
| Consumption Info |
Misoprostol contains hydrogenated castor oil which may cause stomach upset and diarrhoea. |
| Drug quanitty |
To heal ulcers in your stomach or duodenum
You should normally take two 200 microgram Misoprostol twice a day with food.Alternatively you can take one Misoprostol tablet four times a day, at regular intervals with food.Treatment will usually last for 4 weeks, but may be extended up to 8 weeks.If your ulcers are not completely healed after this period, further treatment may be given.
To prevent ulcers when taking NSAID medicines
You should usually take one 200 microgram tablet, two, three or four times a day. Your doctor will adjust your dose to suit you.You will need to continue to take Misoprostol as long as is needed to protect your stomach or gut, and must keep taking the until your doctor advises you to stop |
| Drug Dose |
Always take your medicine exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.Misoprostol is suitable only for adults aged 18 years and over |
| Excess Drug Consumption |
If you take too many , contact your doctor or accident and emergency department straight away. |
| Forgot Drug Consumption |
If you forget to take a dose of your , take them as soon as you remember. But if it is almost time for your next dose, do not take the tablet(s) you have missed.If you have any further questions on the use of this product, ask your doctor or pharmacist |
| Stop Drug Consumption |
|
| Possible Side
Effects
|
| General Information |
|
| Common Drug Side Effects |
Chills, High temperature, Skin rashes and dizziness can occur.Sometimes Misoprostol can be prescribed for uses other than the approved ones of healing or prevention of ulcers (this also called ‘off label’ use). When used in this way the following side effects have been reported:
•Abnormal contractions of the womb,
•bleeding from the womb,
•placenta remaining in the womb after birth, termination or miscarriage,
•amniotic fluid (the fluid which surrounds the baby when pregnant) entering the mother’s bloodstream causing allergic reaction,
•incomplete miscarriage and premature birth. |
| Rare Drug Side Effects |
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| Very Rare Drug Side Effects |
|
| Drug Side Effects Symptoms |
Effects on the stomach and intestines: wind, indigestion, stomach pain,constipation, feeling or being sick. Diarrhoea is the most common problem and is occasionally severe. You have less chance of getting diarrhoea if you take Misoprostol with food.If you use an antacid (something to reduce acid in the stomach) you should avoid antacids with magnesium in them as these may make diarrhoea worse. Your pharmacist can help you choose a suitable antacid.
Effects on the reproductive system: Some women can get period problems including cramp, prolonged heavy bleeding, bleeding between periods, irregular periods and severe uterine
pain. Some older women may have vaginal bleeding even though they have gone through the menopause. |
| How to Store the
Medicine
|
| How to Store the Medicine |
Keep out of the reach and sight of children.Do not use Misoprostol after the expiry date which is stated on the carton or blister strip.Do not store above 30ºC.Store in the original package.Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment. |
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