Mycophenolate mofetil belongs to a group of medicines called immunosuppressants. Immunosuppressants are used to prevent rejection of transplanted organs, and work by stopping your immune system from reacting to the transplanted organ
||Do not take .Mycophenolate mofetil to treat any other complaints unless your doctor tells you to.
Do not give your medicine to anyone else, even if they have the same condition as you.
Do not stop taking your medicine or lower the dosage without checking with your doctor.
Do not let yourself run out of medicine over the weekend or on holidays.
Do not take any other medicines, whether they require a prescription or not, without first telling your doctor or consulting with a pharmacist.
||Do not take Mycophenolate mofetil if you have an allergy to:
any medicine containing mycophenolate mofetil or mycophenolic acid
any of the ingredients listed at the end of this leaflet
Some of the symptoms of an allergic reaction may include: shortness of breath; wheezing or difficulty breathing; swelling of the face, lips, tongue or other parts of the body; rash, itching or hives on the skin.
|Drug Special Care
||Tell your doctor if:
you are pregnant or plan to become pregnant
Women of childbearing potential should have a pregnancy test to show they are NOT pregnant one week before starting to take Mycophenolate mofetil.
Tell your doctor if:
you are breastfeeding or plan to breastfeed
Tell your doctor if you have or have had any medical conditions, including the following:
severe kidney disease
a history of serious stomach or bowel problems (such as ulcers or bleeding)
you have a rare disease such as Lesch-Nyhan or Kelley-Seegmiller syndrome
a history of sun spots or skin cancers
Tell your doctor if you have allergies to any other medicines, foods, preservatives or dyes.
If you have not told your doctor about any of the above, tell him/her before you start taking Mycophenolate mofetil.
|Drug Drug Interactions
||aciclovir, ganciclovir, valaciclovir, valganciclovir, antacids,azathioprine calcium, live vaccines, cholestyramine, rifampicin, ciprofloxacin, amoxicillin plus clavulanic acid, norfloxacin plus metronidazole, tacrolimus
|Drug Pregnancy Interaction
||It is harmful to an unborn baby when taken by a pregnant woman. There have been cases of birth defects reported in patients exposed to Mycophenolate mofetil in combination with other immunosuppressants during pregnancy. If there is a need to take Mycophenolate mofetil. when you are pregnant, your doctor will discuss the risks and benefits to you and the unborn baby.
|Drug Breast feeding Interaction
||It is not known whether .Mycophenolate mofetil passes into breast milk. If you are taking .Mycophenolate mofetil, your doctor may advise you to stop breast-feeding, or to stop taking Mycophenolate mofetil.
|Drug Machinery Interaction
||Be careful driving or operating machinery until you know how Mycophenolate mofetil .affects you. This medicine may cause dizziness, light-headedness and drowsiness in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.
|Drug More Information
||Things you must do
Tell your doctor or go to your nearest Accident and Emergency centre immediately if you think you may have an infection (signs may include fever, chills, local inflammation, sore throat or ulcers in the mouth, but there could be other symptoms), any evidence of unexpected bruising or any unexpected bleeding. These are serious side effects of taking .Mycophenolate mofetil and you may need urgent medical attention.
.Mycophenolate mofetil reduces your body''''s own defence mechanisms to stop you rejecting your transplanted organ. Your body will not be as good at fighting infection as it normally is. People taking .Mycophenolate mofetil often develop more infections than usual.
If you become pregnant while taking this medicine, tell your doctor immediately.
It is important to use very effective contraceptive measures four weeks before you start taking .Mycophenolate mofetil, while you are taking .Mycophenolate mofetil and for six weeks after you stop taking .Mycophenolate mofetil. It is recommended that two reliable forms of contraception be used at the same time if you are sexually active.
Wear protective clothing and use a sunscreen with a high protection factor when outdoors.
Medicines that prevent rejection of transplants, including .Mycophenolate mofetil, can cause a small increase in the risk of getting cancer, particularly skin cancers. You should discuss this with your doctor if it concerns you.
Tell any other doctors, dentists, and pharmacists who treat you that you are taking this medicine.
If you are about to be started on any new medicine, remind your doctor and pharmacist that you are taking .Mycophenolate mofetil.
Tell your doctor if, for any reason, you have not taken your medicine exactly as prescribed.
Tell your doctor if you feel your medicine is not helping your condition.
If you are going to have surgery, tell the surgeon or anaesthetist that you are taking this medicine. It may affect other medicines used during surgery.
If you are about to have any blood tests, tell your doctor that you are taking this medicine. It may interfere with the results of some tests.
Keep all of your doctor’s appointments so that your progress can be checked. Your doctor may do some tests from time to time to make sure the medicine is working and to prevent unwanted side effects.
|How to take the
||Swallow Mycophenolate mofetil tablets and capsules whole with a full glass of water.
If a capsule breaks open or a tablet is crushed accidentally then you should wash off any powder thoroughly with soap and water. If the powder gets in your eyes you should rinse them out with plain water.
When to take it
It is best to take your doses approximately 12 hours apart.
Take your medicine at about the same time(s) each day. Taking it at the same time(s) each day will have the best effect. It will also help you remember when to take it.
It does not matter if you take this medicine before or after food.
If you need to take an antacid, take it at least 2 hours before or 2 hours after your dose of .Mycophenolate mofetil.
How long to take it
Continue taking your medicine for as long as your doctor tells you. It is important to keep taking your medicine even if you feel well. .Mycophenolate mofetil will help ensure your transplanted organ keeps working properly.
||Take Mycophenolate mofetil exactly as prescribed by your doctor.
Your doctor will tell you how much .Mycophenolate mofetil to take each day.
The normal adult dose to prevent rejection is usually 2 g or 3 g per day, depending on which organ has been transplanted. This should be taken as 1 g or 1.5 g in the morning, and another 1 g or 1.5 g at night.
The normal dose for children and adolescents aged 3 months to 18 years to prevent rejection of a kidney transplant depends on their body surface area. Your doctor will determine the daily dose up to a usual maximum of 2 g per day.
Your doctor may adjust your dose depending on your response.
||Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information Swallow .Mycophenolate mofetil tablets and capsules whole with a full glass of water.
If a capsule breaks open or a tablet is crushed accidentally then you should wash off any powder thoroughly with soap and water. If the powder gets in your eyes you should rinse them out with plain water.Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.
If you do not understand the instructions on the box, ask your doctor or pharmacist for help.
Do not halve .Mycophenolate mofetil tablets. Dose equivalence when the tablet is divided has not been established.
|Excess Drug Consumption
||Immediately telephone your doctor or the National Poisons Information Centre (0800 POISON or 0800 764 766) for advice, or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much .Mycophenolate mofetil. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
|Forgot Drug Consumption
||If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.
Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for the dose that you missed.
If you are not sure what to do, ask your doctor or pharmacist.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints.
|Stop Drug Consumption
||it will effect the transplanted organ . hence to be stopped when doctor says
||Tell your doctor as soon as possible if you notice any of the following:
anxiety, depression or confusion
fluid (swelling) in the legs, arms or face
stomach, back, muscle or other pain
skin changes, especially changes in moles or freckles
signs of anaemia such as excessive tiredness, dizziness or looking pale
The above list includes serious side effects that may require medical attention.
|Common Drug Side Effects
||diarrhoea, constipation, nausea (feeling sick) or indigestion
dizziness or shaking
inability to sleep (insomnia)
weight gain or loss
runny or blocked sinuses
|Rare Drug Side Effects
||Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking .Mycophenolate mofetil. This medicine helps most people who have transplants but it may have unwanted side effects in a few people. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical attention if you get some of the side effects.
Patients who receive immunosuppressant medicines may also have a small increase in their risk of developing some types of cancers. You should discuss this with your doctor.
If you are over 65 years of age you may have an increased chance of getting side effects.
|Very Rare Drug Side Effects
||If any of the following happen, tell your doctor immediately or go to Accident and Emergency at your nearest hospital:
any signs of infection such as fever, inflammation, sweating, chills or ''''flu-like’ symptoms
urinary infection or blood in your urine
irregular heartbeat or chest pain
changes in vision or speech
The above list includes very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare.
|Drug Side Effects Symptoms
||Tell your doctor or go to your nearest Accident and Emergency
centre immediately if you think you may have an infection (signs may include fever, chills, local inflammation, sore throat or ulcers in the mouth, but there could be other symptoms), any evidence of unexpected bruising or any unexpected bleeding.
|How to Store the
|How to Store the Medicine
||Keep your capsules and tablets in the blister pack until it is time to take them. If you take the capsules and tablets out of the blister pack they may not keep well.
Keep your capsules and tablets in a cool dry place where they are protected from light and the temperature stays below 25°C.
Do not store .Mycophenolate mofetil or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car. Heat and dampness can destroy some medicines.
Keep it where children cannot reach it. A locked cupboard at least one-and-a half metres above the ground is a good place to store medicines.