ACETAMINOPHEN+NIMESULIDE belongs to a class of medicines known as 'non-steroidal anti-inflammatory drugs (NSAIDs)', primarily indicated in the treatment of mild to moderate pain. Pain can be temporary (acute) or long-lasting (chronic) in nature. ACETAMINOPHEN+NIMESULIDE relieves symptoms of arthritis, dysmenorrhea (painful periods or menstrual cramps) and reduces fever. Acute pain is caused by damage to the tissues of the muscle, bone, or other organs for a short time. While, chronic pain lasts for a long duration and is caused due to pathologies like nerve damage, mild migraine, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, etc. Besides this, it is also useful for dental pain, which can occur due to damage to the tooth nerve, infection, decay, extraction or injury.

ACETAMINOPHEN+NIMESULIDE is composed of two medicines: Nimesulide and Acetaminophen. Nimesulide is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin responsible for inducing pain and inflammation in our body. Acetaminophen acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger (prostaglandin) and promoting heat loss (through sweating) that helps reset the hypothalamic thermostat. Together it helps in reducing mild to moderate pain in a shorter duration.

Take ACETAMINOPHEN+NIMESULIDE as prescribed by your doctor. You are advised to take ACETAMINOPHEN+NIMESULIDE for as long as your doctor has prescribed it for you depending on your medical condition. Like all medicines, ACETAMINOPHEN+NIMESULIDE may cause side effects, although not everybody gets them. Stop taking this medicine if you experience symptoms like chest tightness, breathing difficulties, fever, skin rashes, increased heart rate, and or in case of any signs of hypersensitivity.

Do not take ACETAMINOPHEN+NIMESULIDE if you are allergic to painkillers like aspirin, ibuprofen, naproxen or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. ACETAMINOPHEN+NIMESULIDE may be associated with a small increase in heart attack risk (myocardial infarction). Avoid alcohol consumption as it may damage your liver and cause increased side effects from taking this drug. Consult your doctor if your pain, inflammation and fever symptoms do not disappear even after ten days. ACETAMINOPHEN+NIMESULIDE is usually safe to be taken in pregnancy and breastfeeding females, however, an individual should consult their doctor before taking it. ACETAMINOPHEN+NIMESULIDE is well tolerated by elderly persons.

Pain relief

ACETAMINOPHEN+NIMESULIDE is composed of nimesulide and acetaminophen, primarily used to treat mild to moderate pain. ACETAMINOPHEN+NIMESULIDE is prescribed mainly to treat pain and get relief from discomfort caused by conditions like mild migraine, tooth pain, arthritis, period pain, back pain, cold/ flu pain and other types of short-term pains. Acetaminophen has got the advantage of producing less gastric irritation compared to other painkillers like aspirin.

ACETAMINOPHEN+NIMESULIDE can be taken with or after the meal. It should be swallowed as a whole with a glass of water. Do not crush or chew it. Do not take ACETAMINOPHEN+NIMESULIDE if your pain lasts for more than ten days or fever stays for more than three days, and consult your doctor immediately. Do not take a double dose if you missed one dose.

Store in a cool and dry place away from sunlight

• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Constipation
• Indigestion
• Headache