Activated Polydimethylsiloxane+magaldrate
About Activated Polydimethylsiloxane+magaldrate
Activated Polydimethylsiloxane+magaldrate is a medication used to relieve symptoms of excess stomach acid, such as heartburn, indigestion, and acid reflux. It is also highly effective at relieving pressure, bloating, and gas in the stomach and gut. By targeting both excess acid and trapped gas, it provides comprehensive comfort to your digestive system.
You should take Activated Polydimethylsiloxane+magaldrate exactly as directed by your doctor, typically after meals and at bedtime when acid and gas symptoms are most likely to flare up. To get the best results, take this liquid suspension consistently, shaking the bottle well before each use. Making simple dietary changes, such as avoiding spicy foods and not lying down immediately after eating, can also significantly improve your results.
While Activated Polydimethylsiloxane+magaldrate is generally well-tolerated, some people may experience mild side effects like diarrhoea, constipation, or a chalky taste in the mouth. These effects are usually temporary and go away as your body adjusts to the medication. However, if you experience severe stomach pain, persistent vomiting, or signs of a serious allergic reaction, you should stop taking it and consult your doctor immediately.
Before starting Activated Polydimethylsiloxane+magaldrate, it is important to talk to your doctor if you have kidney disease, as some ingredients can build up in your body if your kidneys are not working fully. Do not take this medicine if you have severe kidney failure or if you have been told by a doctor that you have low phosphate levels in your blood.
This medicine can interfere with how your body absorbs other drugs, so you should space it out from your other medications by at least two hours. Avoid drinking alcohol or smoking while taking Activated Polydimethylsiloxane+magaldrate, as both can irritate your stomach lining and worsen your reflux symptoms. If you are pregnant, breastfeeding, or caring for an elderly individual, talk to your doctor or pharmacist before starting this medicine to ensure it is safe for your specific situation.
Uses of Activated Polydimethylsiloxane+magaldrate
Medicinal Benefits
Activated Polydimethylsiloxane+magaldrate helps provide fast relief from acidity, heartburn, and indigestion by neutralising excess stomach acid and relieving trapped gas. Its liquid formulation acts quickly to soothe digestive discomfort and improve overall comfort.
- Provides Fast Relief from Heartburn and Acidity: As a liquid formulation, Activated Polydimethylsiloxane+magaldrate quickly neutralises excess stomach acid and coats the lining of the food pipe and stomach, helping relieve the burning sensation caused by acid reflux and heartburn.
- Relieves Bloating and Gas: By helping trapped gas combine into larger bubbles that can be expelled more easily, Activated Polydimethylsiloxane+magaldrate helps reduce bloating, abdominal pressure, and discomfort.
- Promotes Lasting Digestive Comfort: By relieving acidity, indigestion, and gas, Activated Polydimethylsiloxane+magaldrate helps you enjoy meals more comfortably and supports better sleep by reducing nighttime heartburn and reflux symptoms.
Directions for Use
- Activated Polydimethylsiloxane+magaldrate should be taken on an empty stomach.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Measure the suggested dose using a measuring cup and administer it orally.
- Avoid using regular household spoons, as they may not measure the dose correctly.
- Shake well before use.
Storage
Side Effects of Activated Polydimethylsiloxane+magaldrate
Common Side Effects (Usually mild):
- Mild diarrhoea
- Mild constipation
- Chalky or unusual taste in the mouth
- Mild nausea
Serious Side Effects (Consult a doctor right away):
- Signs of an allergic reaction, such as a skin rash, itching, hives, swelling of the face, lips, tongue, or throat, and difficulty breathing
- Severe or ongoing muscle weakness
- Severe stomach pain or cramping
- Extreme tiredness, confusion, or changes in mood
- Loss of appetite combined with bone pain
Medicines Containing this Salt
View AllDrug Warnings
- Check the suspension: Before each use, inspect the liquid. It should be a uniform, smooth liquid after shaking; if you notice unusual clumping or discolouration, consult your pharmacist before taking it.
- Avoid long-term self-treatment: Do not use Activated Polydimethylsiloxane+magaldrate for more than two weeks continuously without consulting your doctor, as persistent acid reflux can be a sign of a more serious underlying condition.
- Space out your other medications: This medicine can significantly decrease the absorption of other oral drugs. Always take your other medications at least 2 hours before or 4 to 6 hours after taking Activated Polydimethylsiloxane+magaldrate.
- Monitor kidney function: If you have mild to moderate kidney issues, use this medicine with caution and under medical supervision, as certain minerals can accumulate in your body.
- Check sodium and sugar content: If you are on a restricted diet (such as a low-sodium diet) or have diabetes, ask your pharmacist to check the specific formulation details of your brand of Activated Polydimethylsiloxane+magaldrate.
Drug Interactions
- Antibiotics (Tetracyclines and Fluoroquinolones): Taking Activated Polydimethylsiloxane+magaldrate at the same time can prevent your body from absorbing these antibiotics, making them less effective. Space them out by at least 2 hours.
- Iron Supplements: This medicine can reduce the absorption of iron, lowering its effectiveness in treating iron deficiency.
- Heart Medications (Digoxin): This antacid combination can decrease the absorption of digoxin, potentially reducing its therapeutic effect on your heart.
- Thyroid Hormones (Levothyroxine): Antacids can bind to levothyroxine in the gut, reducing thyroid hormone absorption and its therapeutic effect.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeIt is recommended to avoid alcohol while you are being treated with Activated Polydimethylsiloxane+magaldrate. Alcohol consumption makes the stomach produce more acid, further leading to heartburn.
Pregnancy
cautionThere is limited data on how the Activated Polydimethylsiloxane+magaldrate affects pregnancy. Please consult your doctor if you plan to become pregnant or are already pregnant before starting Activated Polydimethylsiloxane+magaldrate.
Breast Feeding
cautionIt is unknown if Activated Polydimethylsiloxane+magaldrate is excreted into the breast milk while used by a breastfeeding mother. Please consult your doctor before taking Activated Polydimethylsiloxane+magaldrate if you are breastfeeding.
Driving
cautionDo not drive or operate machinery if you experience discomfort while using Activated Polydimethylsiloxane+magaldrate until you feel better.
Liver
cautionPlease take Activated Polydimethylsiloxane+magaldrate with caution and the doctor's advice if you have a history of liver diseases/conditions.
Kidney
cautionPlease take Activated Polydimethylsiloxane+magaldrate with caution and the doctor's advice if you have a history of kidney diseases/conditions.
Children
cautionSafety and efficacy of Activated Polydimethylsiloxane+magaldrate are not established in paediatric patients. Therefore, please consult a doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller, more frequent meals: Large meals can stretch your stomach and put pressure on the muscular valve that keeps acid down, leading to reflux and gas.
- Avoid trigger foods: Limit your intake of spicy, fatty, acidic (like tomatoes and citrus), and caffeinated foods and beverages, as these can trigger excess acid production.
- Stay upright after eating: Avoid lying down or bending over for at least two to three hours after a meal to let gravity keep the acid in your stomach.
- Elevate the head of your bed: If you experience acid reflux at night, raise the head of your bed by 6 to 9 inches using blocks or a wedge pillow.
- Limit carbonated drinks: Sodas and sparkling water introduce extra gas into your digestive tract, worsening bloating and flatulence.
Patients Concern
Disease/Condition Glossary
Dyspepsia (Indigestion): Indigestion is the inability to digest food and is associated with pain and discomfort in the stomach. Symptoms include bloating, abdominal pain, burning sensation in the stomach, gas, and belching.
Flatulence: It is the build-up of gas in the digestive system that can lead to abdominal discomfort.
Acidity: The stomach is usually protected from the acid by a mucous layer. In some cases, the mucous layer gets eroded due to excess acid production, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.
FAQs
Activated Polydimethylsiloxane+magaldrate belongs to a group of medicines called antacids and antiflatulents used to treat acidity, dyspepsia (indigestion), flatulence (gas), heartburn and stomach upset.
Activated Polydimethylsiloxane+magaldrate contains Magaldrate and Activated Polydimethylsiloxane (Dimethicone). Magaldrate works by neutralising excess stomach acid. Activated Polydimethylsiloxane works by decreasing the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping). It also prevents the accumulation and formation of gas in the digestive tract.
Please let your doctor know if you have a history of allergic reactions to medicines, inflammation/swelling of the pancreas (acute pancreatitis), intestinal bleeding, stomach ulcers, colostomy (opening in the large intestine) or ileostomy before starting Activated Polydimethylsiloxane+magaldrate.
Do not stop using Activated Polydimethylsiloxane+magaldrate even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the disease may not be cured completely.
Talk to your doctor if you do not feel better even after taking Activated Polydimethylsiloxane+magaldrate for 14 days. Do not take Activated Polydimethylsiloxane+magaldrate for longer durations unless advised by the doctor.
Avoid taking aluminium and magnesium-containing antacids with Activated Polydimethylsiloxane+magaldrate. Aluminium containing antacids, along with Activated Polydimethylsiloxane+magaldrate could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea.
Activated Polydimethylsiloxane+magaldrate contains Magaldrate, which might affect test results of X-ray, CT scan and MRI scan taken using radioactive dye. Inform the person doing the tests that you are taking Activated Polydimethylsiloxane+magaldrate.
Yes, you can take Activated Polydimethylsiloxane+magaldrate with other medications only if suggested by the doctor. However, consult the doctor before taking Activated Polydimethylsiloxane+magaldrate with cholesterol-lowering drugs (rosuvastatin), antacids (aluminium hydroxide, magnesium hydroxide), painkillers (indomethacin), antibiotics (nitrofurantoin, isoniazid), antipsychotics (chlorpromazine), antiparkinson medicines (levodopa) as these medications may cause interactions.
You should avoid taking Activated Polydimethylsiloxane+magaldrate if you are allergic to any of its ingredients. If you are unsure, it is important to consult the doctor before using Activated Polydimethylsiloxane+magaldrate to ensure it is safe for you.
The side effects of Activated Polydimethylsiloxane+magaldrate include altered taste, constipation, bloating/gas, diarrhoea, nausea, and vomiting. Consult the doctor if any of these side effects persist or worsen.
You should not take Activated Polydimethylsiloxane+magaldrate more than the recommended dose as taking too much may cause nausea, vomiting, diarrhoea, abdominal pain, or bloating. Therefore, always take Activated Polydimethylsiloxane+magaldrate in the suggested dose to prevent adverse effects.
Activated Polydimethylsiloxane+magaldrate should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
Some components of Activated Polydimethylsiloxane+magaldrate are generally considered safe for short-term use during pregnancy, but others can cause fluid retention or other issues if used in large amounts. You should always consult your healthcare provider to weigh the risks and benefits before taking this medicine while pregnant. Talk to your doctor.
It is best to avoid drinking large amounts of water immediately after taking Activated Polydimethylsiloxane+magaldrate liquid suspension, as water can wash the protective coating off your oesophagus and dilute the antacid, reducing its effectiveness. Talk to your doctor or pharmacist if you have questions about how to take your dose.
You should not give Activated Polydimethylsiloxane+magaldrate to young children, especially those under 12 years of age, unless specifically directed to do so by a paediatrician. Children's bodies process minerals differently, and safety must be evaluated by a healthcare professional. Talk to your doctor.
If your heartburn worsens, occurs more frequently, or is accompanied by difficulty swallowing, unexplained weight loss, or black stools, stop taking the medication immediately. These can be signs of a more serious gastrointestinal condition that requires urgent medical attention. Talk to your doctor.

