Apollo
logo
  1. Home
  2. salt
  3. Adapalene+benzoyl Peroxide

Adapalene+benzoyl Peroxide

About Adapalene+benzoyl Peroxide

Adapalene+benzoyl Peroxide is used to treat acne (pimples) and remove the skin's upper dead layer. Acne is a common skin condition and occurs when hair follicles are blocked with dead skin cells and oil. The acne-causing bacteria feeds on sebum (natural oil produced by skin), causing redness and swelling.

Adapalene+benzoyl Peroxide is a combination of two drugs: Adapalene (retinoids) and Benzoyl peroxide (keratolytic agent).  Adapalene belongs to the retinoid class (human-made vitamin A) which works by loosening the cells on the skin’s surface and unblocks pores by reducing oil production in the skin. Thus, it decreases pimples, whiteheads, and blackheads. Benzoyl peroxide is a keratolytic agent that breaks down a protein known as keratin (that forms part of skin structure) removes dead skin cells, and softens skin. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that cause acne.

Take Adapalene+benzoyl Peroxide as prescribed. Adapalene+benzoyl Peroxide is only for external use. Avoid contact of Adapalene+benzoyl Peroxide with nose, ears, mouth, or eyes. In case Adapalene+benzoyl Peroxide comes in contact with these areas accidentally, rinse with warm water thoroughly. Your doctor will advise you how often you take Adapalene+benzoyl Peroxide based on your medical condition. You may experience dry skin, scaling, local skin rash, irritation, redness, or burning sensation of the skin in some cases. Most of these side effects of Adapalene+benzoyl Peroxide do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Adapalene+benzoyl Peroxide or any other medicines, please tell your doctor. Do not apply Adapalene+benzoyl Peroxide on cuts, open wounds, scrapes, sunburned, windburned, chapped, dry, or irritated skin. Avoid exposure to tanning beds or sunlight while using Adapalene+benzoyl Peroxide as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. If you are pregnant or breastfeeding, please inform your doctor before taking Adapalene+benzoyl Peroxide. Do not apply Adapalene+benzoyl Peroxide in large amounts or use it for a longer time than prescribed, as it does not give quick or better results but increases the risk of side effects such as irritation, scaling, or redness of the skin. If you have eczema (itchy, swollen, rough, and cracked skin) or sunburned skin, please inform your doctor before taking Adapalene+benzoyl Peroxide.

Uses of Adapalene+benzoyl Peroxide

Adapalene+benzoyl Peroxide is used in the treatment of acne (pimples). The detailed uses of Adapalene+benzoyl Peroxide are as follows:
• Acne Treatment: Adapalene+benzoyl Peroxide is primarily used to treat moderate to severe acne by combining benzoyl peroxide and adapalene, which helps reduce acne lesions.
• Clogged Pores: Adapalene+benzoyl Peroxide works by unclogging pores, helping to prevent the formation of new pimples and blackheads.
• Reducing Inflammation: The anti-inflammatory properties of Adapalene+benzoyl Peroxide help to reduce redness and swelling associated with acne outbreaks.
• Preventing Acne Scarring: Regular use of Adapalene+benzoyl Peroxide can help reduce the chances of acne scarring, promoting clearer skin over time.
• Improving Skin Texture: By promoting cell turnover and exfoliation, Adapalene+benzoyl Peroxide can lead to smoother skin texture and a more even skin tone.

Medicinal Benefits

Adapalene+benzoyl Peroxide combines two proven acne treatments to help clear existing pimples and prevent new ones from forming. It targets multiple causes of acne, promoting clearer, healthier-looking skin with regular use.
 

  • Clears Existing Acne: Helps reduce blackheads, whiteheads, and inflamed pimples by unclogging pores and reducing skin inflammation.
  • Prevents New Breakouts: Helps stop new acne lesions from developing by preventing blocked pores and reducing acne-causing bacteria.
  • Promotes Clearer Skin: Regular use improves skin texture and helps restore a smoother, more even complexion.
  • Reduces Acne-Related Inflammation: Helps relieve redness, swelling, and tenderness associated with acne.
  • Provides Comprehensive Acne Control: Combines two complementary medicines in one product to target multiple causes of acne and improve treatment effectiveness.
     

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Apply a thin layer of Adapalene+benzoyl Peroxide to the affected area as directed, and gently rub it in.
  • Wash your hands before and after use.
  • Avoid contact with the nose, mouth or eyes. In case of accidental contact with these areas, rinse with water thoroughly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Adapalene+benzoyl Peroxide

Common Side Effects (Usually mild)

  • Dry or peeling skin
  • skin redness or warmth
  • A temporary stinging or burning sensation upon application
  • Itching or mild skin discomfort


Serious Side Effects (Consult your doctor right away)

  • Severe swelling, redness, or crusting of the treated skin
  • Deep, painful cracks or blistering of the skin
  • Signs of a severe allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, or throat
     

Drug Warnings

  • Do Not Apply to Damaged Skin: Avoid using the medicine on cut, scraped, sunburnt, or eczematous skin.
  • Be Aware of Bleaching: Benzoyl peroxide may bleach hair, coloured fabrics, towels, and clothing. Allow the medicine to dry completely before contact with these materials.
  • Wash Your Hands After Application: Wash your hands thoroughly after applying the medicine to avoid accidental contact with your eyes, nose, mouth, or other sensitive areas.
  • Avoid Using Other Medicated Acne Products Without Medical Advice: Unless advised by your doctor, do not use other acne treatments containing salicylic acid, sulphur, or resorcinol at the same time, as this may increase skin irritation.
     

Drug Interactions

Adapalene+benzoyl Peroxide may interact with certain topical medicines and skincare products, increasing the risk of skin irritation. Inform your doctor if you are using any of the following:
 

  • Other topical acne therapies: Products containing salicylic acid, sulphur, or resorcinol can cause cumulative and severe skin irritation when used at the same time as Adapalene+benzoyl Peroxide.
  • Astringents and alcohol-based products: Cosmetics, soaps, or toners with a high concentration of alcohol or drying agents can excessively dry out and irritate the skin.
     

Drug-Drug Interactions Checker List:

  • ISOTRETINOIN
  • TRETINOIN
  • BEXAROTENE
  • TRIFAROTENE
  • AMINOLEVULINIC ACID
  • METHOXSALEN
  • PORFIRMER
  • VERTEPORFIN
  • DAPSONE
  • METHYL AMINOLEVULINATE
  • SALICYLIC ACID
  • SULFUR
  • RESORCINOL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Interaction of Adapalene+benzoyl Peroxide with alcohol is unknown. Please consult a doctor before consuming alcohol while using Adapalene+benzoyl Peroxide.

    • Safety Warning

      Pregnancy

      unsafe

      Adapalene+benzoyl Peroxide is a category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Adapalene+benzoyl Peroxide is excreted in human milk. Therefore, Adapalene+benzoyl Peroxide is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. However, do not apply Adapalene+benzoyl Peroxide on the chest area to avoid the contact of Adapalene+benzoyl Peroxide with the baby.

    • Safety Warning

      Driving

      safe if prescribed

      Adapalene+benzoyl Peroxide usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      safe if prescribed

      If you have any concerns regarding the use of Adapalene+benzoyl Peroxide in patients with Liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      safe if prescribed

      If you have any concerns regarding the use of Adapalene+benzoyl Peroxide in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      caution

      Adapalene+benzoyl Peroxide is not recommended for children below 9 years as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Moisturise Daily: Use a gentle, fragrance-free, non-comedogenic moisturiser to help reduce dryness and peeling.
    • Protect Your Skin from the Sun: Apply a broad-spectrum sunscreen with SPF 30 or higher every day, as Adapalene+benzoyl Peroxide can make your skin more sensitive to sunlight.
    • Avoid Harsh Skincare Products: Do not use abrasive scrubs, alcohol-based toners, or astringents, as they may increase skin irritation.
    • Follow a Healthy Diet: Limiting foods with a high glycaemic index, such as sugary snacks and refined carbohydrates, may help reduce acne flare-ups in some people.
       

    Special Advise

    • Do not squeeze, pop or pick spots as it may worsen them and cause permanent scarring.

    • You are advised to consult a dermatologist if acne persists or worsens after using Adapalene+benzoyl Peroxide for 1 month.

    Patients Concern

    Disease/Condition Glossary

    Acne (pimples): It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. Acne symptoms include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.

    FAQs

    Adapalene+benzoyl Peroxide is used to treat acne, a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads.

    Adapalene+benzoyl Peroxide contains Adapalene and Benzoyl peroxide. Adapalene is a retinoid (man-made vitamin A) that loosens the cells on the skin’s surface and unblocks pores by reducing the production of oil in the skin. Thereby, decreases pimples, spots, whiteheads and blackheads. Benzoyl peroxide is a keratolytic agent that works by breaking down a protein known as keratin (that forms part of skin structure) and removes dead skin cells and softens skin. Additionally, Benzoyl peroxide possesses antibacterial properties and kills bacteria that causes acne.

    No, Adapalene+benzoyl Peroxide is not recommended for eczema (itchy, cracked, swollen or rough skin) patients as it may cause severe irritation. Therefore, if you are suffering from eczema, inform your doctor before using Adapalene+benzoyl Peroxide.

    Yes, Adapalene+benzoyl Peroxide may cause skin irritation as a side effect. However, if the irritation persists or worsens, stop using Adapalene+benzoyl Peroxide and consult a doctor.

    Yes, Adapalene+benzoyl Peroxide may cause dryness of the skin. You can use a moisturizer while using Adapalene+benzoyl Peroxide to prevent dry skin. However, do not apply Adapalene+benzoyl Peroxide and moisturizer at the same time as it may reduce the effectiveness of Adapalene+benzoyl Peroxide. Please consult a doctor before using other products with Adapalene+benzoyl Peroxide.

    Adapalene+benzoyl Peroxide may cause side effects such as skin irritation, skin redness, scaling, dry skin, or burning sensation of the skin. If these side effects persist or worsen, please consult your doctor.

    When you buy moisturizers, cosmetics, or other skincare products, look for non-comedogenic or non-acnegenic. Otherwise, these products may worsen your acne.

    You should use Adapalene+benzoyl Peroxide for as long as it is advised by your doctor for best results. Do not stop using Adapalene+benzoyl Peroxide on your own even if your skin looks clearer to help prevent future breakouts. With continued use, Adapalene+benzoyl Peroxide will continue to clear inflammation and redness caused by acne; prevent blackheads and clogged pores and as a result, restore the skin’s texture and tone.

    Store Adapalene+benzoyl Peroxide at room temperature. Protect from light. Replace the cap tightly after use. Keep it out of reach of children.

    It may take up to 2-3 weeks for your symptoms to improve and may take some time to show significant results. Use Adapalene+benzoyl Peroxide as advised and let your doctor know if your symptoms do not improve or worsen.

    Wash your hands before and after applying Adapalene+benzoyl Peroxide. Before using it, wash the affected area with water. Apply a small amount of Adapalene+benzoyl Peroxide as a thin layer and gently rub on the clean and dry affected area of the skin at night before going to bed. Adapalene+benzoyl Peroxide is only for external use. If you are using Adapalene+benzoyl Peroxide on your face, avoid contact with eyes, nostrils and lips as it may cause irritation. In case Adapalene+benzoyl Peroxide comes in contact with these areas accidentally, rinse with water thoroughly.

    You are recommended to avoid products with strong irritant or drying effects. However, please consult your doctor before using other skincare products with Adapalene+benzoyl Peroxide.

    If you have sensitive skin or conditions like eczema, use Adapalene+benzoyl Peroxide with caution. If you experience severe irritation, consult your doctor immediately.

    No, this medicine is generally not recommended for use during pregnancy due to its retinoid component. Talk to your doctor for safer alternative acne treatments if you are pregnant or planning to become pregnant.

    Yes, this medication has bleaching properties. It can discolor colored fabrics, pillowcases, towels, and even your hair. Let the gel dry completely before lying down, and wash your hands thoroughly after applying.

    Mild peeling is a common reaction. You can manage this by applying a gentle, non-comedogenic, fragrance-free moisturiser. If the peeling becomes severe or painful, talk to your doctor or pharmacist about adjusting your application schedule.

    Yes, you can wear makeup, but you should wait until the gel has absorbed and dried completely on your skin. Choose oil-free, non-comedogenic cosmetics to prevent further pore clogging.

    No, you should apply a thin layer over the entire affected area of your face or body, not just on individual spots. This helps prevent new acne lesions from forming in untreated areas.

    This medicine makes your skin highly sensitive to sunlight and UV rays. You must wear a broad-spectrum sunscreen daily, wear protective clothing, and limit sun exposure. Talk to your doctor if you experience a sunburn.

    It is highly recommended to avoid physical scrubs, exfoliating brushes, or chemical peels while using this medicine, as they can cause severe redness, pain, and skin damage. Talk to your doctor before using any exfoliating products.

    Author Details

    Doctor image
    We provide you with authentic, trustworthy and relevant information.
    Apollo 247 Floating Button