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AMPICILLIN+CLOXACILLIN

About AMPICILLIN+CLOXACILLIN

AMPICILLIN+CLOXACILLIN belongs to the group of medicines called 'antibiotics' used to treat a wide range of bacterial infections. It is a 'broad-spectrum antibiotic' which treats bacterial infections of the ear, nose, throat, bones, lungs, and post-operative wound infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. 

AMPICILLIN+CLOXACILLIN contains two antibiotics, namely: Ampicillin and Cloxacillin. AMPICILLIN+CLOXACILLIN works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby kills the bacteria and helps in treating and preventing bacterial infections.
 
The dose and duration of AMPICILLIN+CLOXACILLIN may vary depending upon your condition and the severity of the infection. In some cases, AMPICILLIN+CLOXACILLIN may cause common side-effects such as diarrhoea, rashes, nausea, and vomiting. Most of these side-effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take AMPICILLIN+CLOXACILLIN on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side-effects. Inform your doctor about your health condition and medications to rule out any unpleasant side-effects/interactions.

Uses of AMPICILLIN+CLOXACILLIN

Treatment of Bacterial infections

Medicinal Benefits

AMPICILLIN+CLOXACILLIN belongs to the group of antibiotic medicines called penicillins. AMPICILLIN+CLOXACILLIN is composed of two antibiotics, namely: ampicillin and cloxacillin. It is used to treat bacterial infections of the ear, nose, throat, bones, lungs, and post-operative wound infections. It is a broad-spectrum antibiotic which is effective against both gram-positive and gram-negative bacteria. AMPICILLIN+CLOXACILLIN works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby kills the bacteria and helps in treating and preventing bacterial infections.

Directions for Use

Take AMPICILLIN+CLOXACILLIN 30-60minutes before meals as food may cause reduced absorption. Tablet/capsule: Swallow the tablet/capsule as a whole with water; do not crush or chew it. Oral liquid/syrup/suspension/drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Dry syrup: Check the label for directions before use. Add boiled and cooled water up to the mark on the bottle and shake vigorously. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Reconstituted suspension/syrup should be used within five days of preparation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of AMPICILLIN+CLOXACILLIN

  • Diarrhoea
  • Rash
  • Nausea
  • Vomiting

Drug Warnings

Before starting AMPICILLIN+CLOXACILLIN, please inform your doctor if you have any allergy to any penicillin antibiotics, kidney/liver problems, infectious mononucleosis (viral infection with sore throat and fever), or leukaemia (blood cancer). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking AMPICILLIN+CLOXACILLIN if you had diarrhoea after taking antibiotics or inflammation of the bowel. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking AMPICILLIN+CLOXACILLIN to prevent unpleasant side-effects.

Drug Interactions

Drug-Drug Interactions: AMPICILLIN+CLOXACILLIN may interact with sulphonamides, bacteriostatic drugs, combined oral contraceptives, drugs used to decrease uric acid (allopurinol), and pain killers (aspirin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have/had colitis (inflammation in the lining of the intestine or colon), bone marrow toxicity (blood cancer), and mononucleosis (viral infection with sore throat and fever).

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • ALLOPURINOL
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Limit consuming alcohol while taking AMPICILLIN+CLOXACILLIN to avoid unpleasant side-effects.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are pregnant; your doctor will prescribe AMPICILLIN+CLOXACILLIN only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Please consult your doctor if you are breastfeeding; your doctor will decide if AMPICILLIN+CLOXACILLIN can be taken by breastfeeding mother's or not.

    • Safety Warning

      Driving

      safe

      AMPICILLIN+CLOXACILLIN does not affect your ability to drive.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease before taking AMPICILLIN+CLOXACILLIN.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Please consult your doctor if you have kidney impairment/kidney disease before taking AMPICILLIN+CLOXACILLIN.

    • Safety Warning

      Children

      safe if prescribed

      AMPICILLIN+CLOXACILLIN is safe for children if prescribed by a doctor. The dose and duration may vary depending upon the age and severity of the infection.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

    • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

    • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

    • Avoid consumption of alcohol and usage of tobacco.

    Patients Concern

    Disease/Condition Glossary

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any body part and multiply very quickly. Symptoms of bacterial infection include chills, fever, headache, nausea, vomiting, diarrhoea, abdominal pain, and loss of appetite. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.

    FAQs

    AMPICILLIN+CLOXACILLIN is used to treat a wide range of bacterial infections. It is used to treat bacterial infections of the ear, nose, throat, bones, lungs, and post-operative wound infections.

    AMPICILLIN+CLOXACILLIN works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby kills the bacteria and helps in treating and preventing bacterial infections.

    Diarrhoea might be a side-effect of AMPICILLIN+CLOXACILLIN. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking AMPICILLIN+CLOXACILLIN and consult your doctor. Do not take anti-diarrhoeal medicine on your own.

    Even if you feel better, it is recommended to complete the course of AMPICILLIN+CLOXACILLIN as prescribed by the doctor as it is an antibiotic, and stopping it in between may lead to antibiotic resistance.

    Pseudomembranous colitis (swelling or inflammation of the large intestine) has been reported with the use of antibiotics. If you experience prolonged or significant diarrhoea with abdominal cramps, stop taking AMPICILLIN+CLOXACILLIN and consult your doctor immediately.

    AMPICILLIN+CLOXACILLIN may affect certain laboratory test results. Inform the person doing the tests that you are taking AMPICILLIN+CLOXACILLIN.

    AMPICILLIN+CLOXACILLIN may affect the gut flora leading to decreased oestrogen reabsorption and lowered efficacy of combined oral contraceptives. Use other methods of contraception while on treatment with AMPICILLIN+CLOXACILLIN. Consult your doctor if you have any concerns.

    Your doctor will determine the duration of your treatment. If you have any concerns about using AMPICILLIN+CLOXACILLIN, consult your doctor.

    AMPICILLIN+CLOXACILLIN is not recommended as it is ineffective against colds, flu, or other viral infections. Using antibiotics unnecessarily increases the risk of developing antibiotic-resistant infections in the future. Therefore, please consult a doctor before use. Do not self-medicate.

    AMPICILLIN+CLOXACILLIN should be taken 30 to 60 minutes before meals as food can reduce absorption or as advised by your doctor.

    No, they are not the same. AMPICILLIN+CLOXACILLIN is a combination of ampicillin and cloxacillin. While amoxicillin is a single antibiotic. AMPICILLIN+CLOXACILLIN and amoxicillin are penicillin-based antibiotics but are used for treating bacterial infections.

    The dose and frequency will be decided by your doctor based on your medical condition. Follow your doctor’s instructions.

    AMPICILLIN+CLOXACILLIN usually begins to work shortly after you start taking it. However, it may take a few days to eliminate all harmful bacteria and improve your symptoms.

    AMPICILLIN+CLOXACILLIN should be avoided with methotrexate, used to treat rheumatoid arthritis, psoriasis, and certain types of cancer, as their combination may lead to serious side effects. However, you are recommended to consult your doctor before taking other medicines with AMPICILLIN+CLOXACILLIN to avoid potential interactions.

    AMPICILLIN+CLOXACILLIN causes side effects such as diarrhoea, rash, nausea and vomiting. These gradually reduce over time. However, consult the doctor if persists longer durations.

    AMPICILLIN+CLOXACILLIN may interact with sulfonamides, bacteriostatic medications, oral contraceptives, medicines that lower uric acid levels (like allopurinol), and aspirin (pain reliever). Therefore, consult your doctor before taking other medicines while on treatment with AMPICILLIN+CLOXACILLIN.

    If you are pregnant, breastfeeding, think you might be pregnant or are planning to have a baby, consult your doctor for advice before using AMPICILLIN+CLOXACILLIN. It is recommended by doctor only if the benefits overweigh the risks.

    If you have taken more than the recommended doses of AMPICILLIN+CLOXACILLIN, seek medical help right away by contacting your doctor.

    Available Medicines for

    AMPICILLIN+CLOXACILLIN

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