ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE belongs to a group of anti-malarial drugs used to treat uncomplicated falciparum malaria. Malaria is a mosquito-borne disease caused by the female anopheles mosquito. Malaria is transmitted through the bite of infected mosquitoes, which carry the Plasmodium parasite. The symptoms usually develop within 10 days to 4 weeks after the infection.
ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. Artesunate generates free radicals, thereby inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during erythrocytic stages. Pyrimethamine binds to haem and forms a complex which is toxic to the malarial parasite. Sulphadoxine prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE helps in treating malaria.
Take ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE with food. It is advised to take ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE for as long as your doctor has prescribed, depending on your medical condition. In some cases, ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE may cause nausea, vomiting, dizziness, abdominal pain, headache, diarrhoea, and fatigue. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor before taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE if you are pregnant. Avoid breastfeeding while taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE. ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE may cause dizziness, so drive only if you are alert. ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE as it could lead to increased dizziness. Keep your doctor informed about the medicines you take and your health condition to rule out any side effects.
Malaria
ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE is a combination medicine that contains Artesunate, Pyrimethamine, and Sulphadoxine. ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE belongs to a group of medicines called anti-malarial drugs used to treat uncomplicated Plasmodium falciparum malaria. Artesunate is an anti-parasitic agent that generates free radicals, inhibiting nucleic acid and protein synthesis of the Plasmodium parasites during the erythrocytic stages. Pyrimethamine is an antiparasitic agent that binds to haem and forms a complex toxic to the malarial parasite. Sulphadoxine is an antibiotic that prevents the parasite from producing folinic acid, which is necessary for their multiplication. Together, ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE helps in treating malaria.
Do not take ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE if you are allergic to any of its contents. Inform your doctor before taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE if you have epilepsy, asthma, blood problems, depression, schizophrenia, bipolar disorder, severe anxiety, glucose-6-phosphate dehydrogenase deficiency, stomach or intestinal infection, heart, kidney, or liver problems. Consult your doctor before taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE if you are pregnant. Avoid breastfeeding while taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE. ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE may cause dizziness, so drive only if you are alert. ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE should be given to children only if prescribed by the doctor. Avoid consuming alcohol along with ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE as it could lead to increased dizziness. Consult your doctor immediately if you notice signs of infection, unusual tiredness, skin rash, unusual bleeding or bruising, red, swollen, or blistered skin.
Drug-Drug Interactions: ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE may have interaction with anticonvulsant (carbamazepine, phenytoin), antiretroviral (ritonavir, nevirapine), antibiotics (rifampin), anti-malarial (chloroquine), antimetabolite (methotrexate).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE may interact with depression, schizophrenia, bipolar disorder, seizure, colitis, and porphyria.
Avoid consumption of alcohol while taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE as it may lead to increased dizziness.
Consult your doctor before taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE passes into breastmilk. Avoid breastfeeding while taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE.
ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE may cause dizziness. Do not drive or operate machinery unless you are alert.
ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE should be used with caution in patients with liver problems. Consult your doctor before taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE if you have a liver impairment or any concerns regarding this.
Consult your doctor before taking ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE if you have kidney impairment or any concerns regarding this.
ARTESUNATE+PYRIMETHAMINE+SULPHADOXINE should be given to children aged 6 months and older only if advised by the doctor.
Malaria: Malaria is a blood disease spread by the female anopheles mosquito. Malaria is spread through the bite of an infected mosquito carrying the Plasmodium parasite. The parasite is released into the bloodstream when an infected mosquito bites a person. The parasite develops in the liver before infecting red blood cells. It then multiplies in red blood cells, resulting in malarial infection. Malaria symptoms include fever, headache, exhaustion, muscle pain, back pain, chills, sweating, nausea, vomiting, and a dry cough. Symptoms typically appear 10 days to 4 weeks after infection.