About BEMPEDOIC ACID+EZETIMIBE
BEMPEDOIC ACID+EZETIMIBE is used to lower the levels of bad cholesterol called low-density lipoprotein (LDL), a type of fat in the blood. BEMPEDOIC ACID+EZETIMIBE is given when the other anti-hyperlipidemic medicines like statin (such as simvastatin, a commonly used medicine that treats high cholesterol), bempedoic acid and ezetimibe are not effective in treating your cholesterol (LDL) levels when taken individually. High cholesterol, known as hyperlipidemia or dyslipidemia, occurs when there is an excess of the unhealthy cholesterol balance in the blood.
BEMPEDOIC ACID+EZETIMIBE contains Bempedoic acid and Ezetimibe. Bempedoic acid decreases cholesterol production in the liver and increases the removal of LDL cholesterol from the blood. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract.
Take BEMPEDOIC ACID+EZETIMIBE as prescribed. Your doctor will advise how often you take BEMPEDOIC ACID+EZETIMIBE based on your medical condition. Sometimes, BEMPEDOIC ACID+EZETIMIBE may cause common side effects such as headache, dizziness, diarrhoea, constipation, dry mouth, cough, back pain, unusual tiredness or weakness, nausea and pain in the shoulders, legs or arms. Most of these side effects of BEMPEDOIC ACID+EZETIMIBE do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Bempedoic acid, Ezetimibe, or any other medicines, please tell your doctor. If you are a pregnant or nursing mother, avoid taking BEMPEDOIC ACID+EZETIMIBE. If you feel dizzy after taking BEMPEDOIC ACID+EZETIMIBE, avoid driving or operating machinery. Your doctor may recommend a blood test before you start taking BEMPEDOIC ACID+EZETIMIBE with a statin to check your liver function.
Uses of BEMPEDOIC ACID+EZETIMIBE
High cholesterol
Medicinal Benefits
BEMPEDOIC ACID+EZETIMIBE belongs to the class of medicines called 'antihyperlipidemic drugs' or cholesterol-lowering agents. It consists of Bempedoic acid and Ezetimibe. BEMPEDOIC ACID+EZETIMIBE is used for adults with primary hypercholesterolaemia or mixed dyslipidaemia, which are conditions that cause a high cholesterol level in the blood. It is given in addition to a cholesterol-lowering diet. By reducing cholesterol levels, it lowers the risk of cardiovascular events like heart attack and stroke.
Directions for Use
Storage
Side Effects of BEMPEDOIC ACID+EZETIMIBE
- Headache
- Dizziness
- Diarrhoea
- Constipation
- Dry mouth
- Cough
- Back pain
- Unusual tiredness or weakness
- Nausea
- Pain in the shoulders, legs or arms
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Bempedoic acid, Ezetimibe, or any other medicines, please tell your doctor. Before starting treatment with BEMPEDOIC ACID+EZETIMIBE, you should confirm you are not pregnant and are using effective contraception, as advised by your doctor. If you use contraceptive pills and suffer from an episode of vomiting or diarrhoea that lasts more than 2 days, you must use an alternative contraceptive method (e.g. condoms, diaphragm) for 7 days following resolution of symptoms. If you decide that you would like to become pregnant after you have started treatment with BEMPEDOIC ACID+EZETIMIBE, tell your doctor, as your treatment will need to be changed. If you are a pregnant or nursing mother, avoid taking BEMPEDOIC ACID+EZETIMIBE. If you feel dizzy after taking BEMPEDOIC ACID+EZETIMIBE, avoid driving or operating machinery. Your doctor may recommend a blood test before you start taking BEMPEDOIC ACID+EZETIMIBE with a statin to check your liver function. Maintain a low-fat diet along with BEMPEDOIC ACID+EZETIMIBE for effective results.
Drug Interactions
Drug-Drug Interaction: If you are taking other cholesterol-lowering drugs (pravastatin, rosuvastatin, simvastatin, atorvastatin, fluvastatin, pitavastatin, fenofibrate, colestyramine), a medicine used to manage high blood pressure in the lungs (bosentan), a drug used to treat high blood pressure and heart failure (fimasartan), medicines used to treat hepatitis C (grazoprevir, voxilaprevir, asunaprevir, glecaprevir), immunosuppressant (ciclosporin), and blood thinners (warfarin, acenocoumarol, fluindione, phenprocoumon), inform your doctor.
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you ever have gout or severe kidney or liver problems, inform your doctor before taking BEMPEDOIC ACID+EZETIMIBE.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorThe interaction of alcohol with BEMPEDOIC ACID+EZETIMIBE is unknown. If you have any concerns, please discuss them with your doctor.
Pregnancy
unsafeBEMPEDOIC ACID+EZETIMIBE is not recommended during pregnancy as it may harm the unborn baby. You are advised to use effective contraceptive methods while using BEMPEDOIC ACID+EZETIMIBE. If pregnancy occurs while on treatment with BEMPEDOIC ACID+EZETIMIBE, stop taking BEMPEDOIC ACID+EZETIMIBE and consult your doctor immediately.
Breast Feeding
consult your doctorIt is unknown whether BEMPEDOIC ACID+EZETIMIBE is excreted in the breast milk. If you are a breastfeeding mother, inform your doctor before taking BEMPEDOIC ACID+EZETIMIBE. Your doctor will weigh the benefits and risks before prescribing this medicine.
Driving
cautionBEMPEDOIC ACID+EZETIMIBE has a minor influence on driving. Some people may feel dizzy after taking BEMPEDOIC ACID+EZETIMIBE. Avoid driving or operating machinery if your ability to react is reduced.
Liver
cautionBEMPEDOIC ACID+EZETIMIBE is not recommended if you have moderate or severe liver problems. So, inform your doctor if you have any liver problems before taking BEMPEDOIC ACID+EZETIMIBE.
Kidney
cautionIf you have a severe kidney problem, inform your doctor before taking BEMPEDOIC ACID+EZETIMIBE. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.
Children
unsafeBEMPEDOIC ACID+EZETIMIBE is not recommended for children and adolescents below 18 years of age as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
- Eat a healthy diet that includes fish, poultry, fruits, vegetables, whole grains, nuts, cut-down beverages, and processed and sugary foods.
- Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight, as obesity also raises bad cholesterol and lowers good cholesterol.
- Avoid smoking and alcohol consumption.
Patients Concern
Disease/Condition Glossary
High cholesterol: It is also known as hyperlipidemia or dyslipidemia and occurs when there is an excess of the unhealthy cholesterol balance in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. There are two types of cholesterol found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps reduce the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.
