Bilastine+montelukast
About Bilastine+montelukast
Bilastine+montelukast is a prescription medicine used to relieve the symptoms of seasonal and year-round allergies, especially when they are accompanied by asthma. It helps control allergic reactions by targeting two different pathways in your body that cause inflammation and airway swelling. This combination tablet provides effective, daily relief from sneezing, an itchy or runny nose, and breathing difficulties.
For the best results, you should take Bilastine+montelukast consistently at the same time every day. It must be taken on an empty stomach—either one hour before or two hours after eating food or drinking fruit juice—as food significantly reduces how well the medicine is absorbed. Combining this treatment with simple lifestyle adjustments, like keeping your windows closed during high-pollen seasons, can help improve your overall symptom control.
While Bilastine+montelukast is generally well-tolerated, some people may experience mild side effects such as drowsiness, headache, or dizziness. If you experience severe side effects, such as unusual mood changes, severe skin rashes, or swelling of the face, stop taking the medicine and consult your doctor immediately.
Before starting this medication, it is important to tell your doctor if you have a history of kidney issues, liver damage, or mental health conditions like depression. Do not take this if you have a known allergy to any of its active ingredients.
This medicine can interact with certain other treatments and substances; for example, taking it with antifungal medicines can increase the risk of side effects, while alcohol can make you feel more drowsy. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist before starting this medicine to ensure it is safe for you.
Uses of Bilastine+montelukast
• Asthma Management: Bilastine+montelukast is commonly used to prevent and manage asthma symptoms by reducing inflammation in the airways.
• Allergic Rhinitis: Bilastine+montelukast helps alleviate symptoms associated with seasonal or year-round allergic rhinitis, such as sneezing, runny or itchy nose, and nasal congestion.
• Exercise-Induced Bronchoconstriction: Bilastine+montelukast can be prescribed to prevent breathing difficulties that may occur during or after exercise, helping individuals maintain their physical activity.
• Reduction of Inflammation: It assists in the inflammatory response in the respiratory system, making it beneficial for individuals with respiratory conditions related to inflammation.
Medicinal Benefits
Bilastine+montelukast provides the following benefits when used as prescribed:
- Targets Allergy Triggers: This medicine helps you feel better by directly targeting the biological triggers of your allergies.
- Relieves Allergy Symptoms: By blocking the substances that cause swelling and mucus production, Bilastine+montelukast makes it easier to breathe and helps you go about your day without constant sneezing, congestion, or itching.
- Improves Sleep: Another major benefit is improved sleep and daily productivity. Since allergy symptoms often worsen at night, managing them effectively helps you rest better, leaving you feeling more alert, active, and focused during the day.
Directions for Use
- Bilastine+montelukast can be taken with or without food. However, avoid taking it with fruit juices, such as orange, apple, or grapefruit, as they may reduce its effectiveness.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Bilastine+montelukast as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Bilastine+montelukast
Common Side Effects (Usually mild):
- Headache
- Drowsiness or sleepiness
- Dizzines
- Mild stomach discomfort or pain
Serious Side Effects (Consult your doctor right away):
- Severe allergic reactions, such as swelling of the face, lips, tongue, or throat, or difficulty breathing
- Significant changes in mood or behavior, including anxiety, agitation, aggression, depression, or sleep disturbances
- Severe skin rashes, itching, or blistering
Medicines Containing this Salt
View AllDrug Warnings
- Take on an empty stomach: Food and fruit juices heavily interfere with how this medicine works. Always stick to the rule of taking it one hour before or two hours after eating.
- Monitor your mood: Pay close attention to any sudden changes in your mood, thoughts, or behavior. If you feel unusually anxious, irritable, or depressed, contact your doctor immediately.
- Be careful when driving: Since this medicine can cause drowsiness or dizziness in some people, avoid driving, operating machinery, or performing tasks that require full alertness until you know how it affects you.
- Limit alcohol: Avoid drinking alcohol while taking Bilastine+montelukast, as it can worsen drowsiness and impair your coordination.
Drug Interactions
Some medicines may affect how Bilastine+montelukast works or increase the risk of side effects:
- Ketoconazole or Erythromycin: Taking these antifungal or antibiotic medications with Bilastine+montelukast may increase the levels of the allergy medicine in your body, potentially raising the risk of side effects.
- Rifampicin: This antibiotic may lower the levels of Bilastine+montelukast in your body, making it less effective.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid drinking alcohol while taking this medicine as it can worsen your side effects like drowsiness.
Pregnancy
consult your doctorThe safety of Bilastine+montelukast in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
consult your doctorIt is unknown whether Bilastine+montelukast is excreted in human milk. It is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.
Driving
cautionAvoid doing any work that needs complete attention, including driving, as this drug may make a person drowsy.
Liver
consult your doctorTake Bilastine+montelukast with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
consult your doctorTake Bilastine+montelukast with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeBilastine+montelukast is not recommended for children below 12 years as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Avoid fruit juices: Do not drink grapefruit, orange, or apple juice within two hours of taking Bilastine+montelukast, as they can significantly reduce how much medicine your body absorbs.
- Track your triggers: Keep a journal to identify what triggers your allergy or asthma symptoms, such as pollen, pet dander, or dust mites, so you can minimize your exposure.
- Keep indoor air clean: Use air purifiers with HEPA filters and keep windows closed during high-pollen seasons to reduce indoor allergens.
- Stay hydrated: Drinking plenty of water helps thin out mucus in your airways, making it easier to breathe.
Patients Concern
Disease/Condition Glossary
Allergies: Allergies or Allergic rhinitis is a natural response of the immune system against a substance called an allergen. Hypersensitive responses can happen with anyone, regardless of whether they have not had sensitivities previously. There is a possibility that a person may build up a sensitivity after coming in contact with an allergen more than once. Mild allergy symptoms include wheezing, a runny or blocked nose, swollen, watery eyes, or skin itching. Serious signs of an allergy are difficulty breathing, a rash, or hives. Hypersensitivity is an unexpected response that sometimes turns into a dangerous response and needs quick treatment.
FAQs
Bilastine+montelukast is used to treat allergic conditions such as asthma, allergic rhinitis (hay fever), and exercise-induced breathing difficulties. It helps reduce inflammation and allergy symptoms like sneezing, runny nose, itching, and nasal congestion, improving overall breathing comfort.
Bilastine+montelukast combines two drugs: Montelukast (leukotriene receptor antagonist) and Bilastine (antihistamine). Montelukast blocks the action of chemicals called leukotrienes released from the lungs, causing inflammation (swelling) and increased mucus production in the airways. Thereby reducing inflammation, mucus production, and narrowing in the airways. Bilastine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness.
You should avoid taking fruit juices like orange, apple or grapefruit with Bilastine+montelukast as they may reduce the effectiveness of Bilastine+montelukast.
Yes, Bilastine+montelukast may cause drowsiness. It is not necessary for everyone taking Bilastine+montelukast to experience this side effect. Therefore, avoid driving if you feel drowsy or dizzy after taking Bilastine+montelukast.
Therapy with leukotriene receptor antagonists like Montelukast may worsen the symptoms of psychotic events in patients with a history of mental illness. Careful administration and monitoring are essential before taking Bilastine+montelukast in patients with neuropsychiatric disorders. Please consult your doctor before taking Bilastine+montelukast if you have been diagnosed or have a history of mental illness like depression, seizures (fits) etc.
Stopping Bilastine+montelukast without consulting a doctor may cause drug withdrawal symptoms that can worsen allergies. It is better to ask the doctor even if you are feeling better, as sometimes the doctor prefers to lower the strength of the drug.
No, you should not take Bilastine+montelukast with food. Food significantly reduces the absorption and effectiveness of this medicine. Take it at least one hour before or two hours after eating. Talk to your doctor or pharmacist if you have trouble scheduling your doses.
No, Bilastine+montelukast is not a rescue inhaler and should not be used to treat a sudden, acute asthma attack. Always use your prescribed quick-relief inhaler for sudden breathing emergencies. Talk to your doctor about managing sudden symptoms.
It is highly recommended to avoid alcohol while taking Bilastine+montelukast. Alcohol can increase the risk of drowsiness, dizziness, and impaired concentration. Talk to your doctor or pharmacist if you have questions about alcohol use.
If you notice any unusual changes in your mood, behavior, or sleep patterns, such as anxiety, aggression, or depression, stop taking the medicine and contact your doctor immediately. Talk to your doctor to find a safer alternative.
The safety of this medicine during pregnancy is not fully established. If you are pregnant, planning to become pregnant, or breastfeeding, you should talk to your doctor or pharmacist to weigh the benefits against potential risks before taking this medicine.
You should not take other antihistamines with Bilastine+montelukast unless specifically advised by your doctor, as this can increase the risk of side effects like severe drowsiness. Talk to your doctor or pharmacist before combining any over-the-counter allergy medicines.

