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Caffeine+ergotamine+prochlorperazine+paracetamol

About Caffeine+ergotamine+prochlorperazine+paracetamol

Caffeine+ergotamine+paracetamol+prochlorperazine is indicated to treat and prevent migraine. Caffeine+ergotamine+paracetamol+prochlorperazine is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack. Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift.

Caffeine+ergotamine+paracetamol+prochlorperazine is a combination of four drugs, namely: Ergotamine (ergot alkaloid), caffeine (methylxanthine), prochlorperazine (anti-emetic) and paracetamol (analgesic). Ergotamine works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect, which is the narrowing of blood vessels. Prochlorperazine prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.

You are advised to take Caffeine+ergotamine+paracetamol+prochlorperazine as directed by your doctor, depending on your medical condition. In some cases, you may experience specific common side effects, such as stomach upset, dizziness, dry mouth, constipation, and insomnia (trouble sleeping). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Caffeine+ergotamine+paracetamol+prochlorperazine contains paracetamol; do not take other medicines containing paracetamol along with Caffeine+ergotamine+paracetamol+prochlorperazine unless prescribed. Do not take Caffeine+ergotamine+paracetamol+prochlorperazine if you are pregnant or breastfeeding. Caffeine+ergotamine+paracetamol+prochlorperazine may cause drowsiness and dizziness, so drive with caution. Caffeine+ergotamine+paracetamol+prochlorperazine should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Caffeine+ergotamine+paracetamol+prochlorperazine as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and any medications you're taking to rule out any side effects or interactions.

Uses of Caffeine+ergotamine+prochlorperazine+paracetamol

Caffeine+ergotamine+paracetamol+prochlorperazine is used in the treatment of migraine. The detailed uses of Caffeine+ergotamine+paracetamol+prochlorperazine are as follows:
  • Migraine Relief: Caffeine+ergotamine+paracetamol+prochlorperazine, mainly used to relieve the headache, nausea, and light and sound sensitivity that come with migraines.
  • Pain management: By reducing moderate to severe migrainous pain, this medication can help patients feel more comfortable during an attack.
  • Preventive Treatment: In certain situations, Caffeine+ergotamine+paracetamol+prochlorperazine may be used to help people who experience frequent migraines by reducing the frequency and severity of their attacks.
  • Symptomatic Management: After an episode, it can help people quickly resume their regular activities by managing their acute migraine symptoms.

Medicinal Benefits

Caffeine+ergotamine+paracetamol+prochlorperazine is a combination of four drugs, namely: Ergotamine, caffeine, prochlorperazine, and paracetamol. Caffeine+ergotamine+paracetamol+prochlorperazine is indicated to treat and prevent migraine. Ergotamine is an ergot alkaloid that works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Caffeine is a methylxanthine that enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine is an anti-emetic that prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol is an analgesic that blocks the release of prostaglandins that cause pain. Caffeine+ergotamine+paracetamol+prochlorperazine is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack.

Directions for Use

• Take Caffeine+ergotamine+paracetamol+prochlorperazine with or without food as advised by a doctor. • Follow your doctor’s recommendations on the dosage and timing of this medication based on your medical conditions to achieve optimal results. • Swallow it as a whole with a glass of water. • Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Caffeine+ergotamine+prochlorperazine+paracetamol

  • Stomach upset
  • Dizziness
  • Dry mouth
  • Constipation
  • Insomnia (trouble sleeping)

Drug Warnings

Do not take Caffeine+ergotamine+paracetamol+prochlorperazine if you are allergic to any of its contents; if you have/had heart problems, blood circulation problems or if you are taking antibiotics, anti-fungal, anti-HIV or other anti-migraine medicines. Caffeine+ergotamine+paracetamol+prochlorperazine, when taken along with antibiotics, anti-fungal, anti-HIV drugs, could lead to unpleasant side-effects such as poor blood flow to hands, feet, or brain. Caffeine+ergotamine+paracetamol+prochlorperazine contains paracetamol, do not take other medicines containing paracetamol along with Caffeine+ergotamine+paracetamol+prochlorperazine unless prescribed. Inform your doctor before taking Caffeine+ergotamine+paracetamol+prochlorperazine if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take Caffeine+ergotamine+paracetamol+prochlorperazine if you are pregnant or breastfeeding. Caffeine+ergotamine+paracetamol+prochlorperazine may cause drowsiness and dizziness, so drive only if you are alert. Caffeine+ergotamine+paracetamol+prochlorperazine is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Caffeine+ergotamine+paracetamol+prochlorperazine as it could lead to increased drowsiness. Do not take any other NSAIDs for pain relief along with Caffeine+ergotamine+paracetamol+prochlorperazine unless prescribed.

Drug Interactions

Drug-Drug Interactions: Caffeine+ergotamine+paracetamol+prochlorperazine may interact with antibiotics (clarithromycin, erythromycin, troleandomycin), anti-fungal (itraconazole, ketoconazole), anti-HIV medicines (indinavir, nelfinavir, ritonavir), decongestant (oxymetazoline), pain killers (acetaminophen, butalbital, fentanyl), anti-depressant (fluoxetine, duloxetine), anti-anxiety (diazepam, lorazepam, alprazolam), antacid (ranitidine), antihistamine (diphenhydramine), anti-convulsant (pregabalin), anti-hypertensive (metoprolol), bronchodilators (albuterol), anti-emetic (ondansetron).

Drug-Food Interactions: Avoid the consumption of alcohol, smoking, and caffeinated products. Do not consume grapefruit while taking Caffeine+ergotamine+paracetamol+prochlorperazine.

Drug-Disease Interactions: Inform your doctor if you have high blood pressure, vasospastic reactions, heart problems, bipolar disorder, psychotic disorders, seizure disorders, gastroesophageal reflux disease, liver or kidney problems.

Drug-Drug Interactions Checker List:

  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TROLEANDOMYCIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • INDINAVIR
  • NELFINAVIR
  • RITONAVIR
  • OXYMETAZOLINE
  • ACETAMINOPHEN
  • FENTANYL
  • BUTALBITAL
  • FLUOXETINE
  • DULOXETINE
  • DIAZEPAM
  • LORAZEPAM
  • ALPRAZOLAM
  • RANITIDINE
  • DIPHENHYDRAMINE
  • PREGABALIN
  • METOPROLOL
  • ALBUTEROL
  • ONDANSETRON
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Caffeine+ergotamine+paracetamol+prochlorperazine as it may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      unsafe

      Avoid taking Caffeine+ergotamine+paracetamol+prochlorperazine if you are pregnant or planning for pregnancy. Please consult your doctor if you are pregnant or if you have any concerns regarding this.

    • Safety Warning

      Breast Feeding

      unsafe

      Caffeine+ergotamine+paracetamol+prochlorperazine may pass into breastmilk. Avoid taking Caffeine+ergotamine+paracetamol+prochlorperazine if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      Caffeine+ergotamine+paracetamol+prochlorperazine may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Caffeine+ergotamine+paracetamol+prochlorperazine should not be given to children as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain a healthy diet and exercise regularly, as it helps in improving overall health and boosts self-esteem.
    • Avoid bright lights, loud noises, and extreme temperatures.
    • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
    • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
    • Massage your scalp to ease the pain.
    • Lie down in a quiet, dark room.
    • Avoid smoking, alcohol, and caffeinated drinks. 
    • Learn what triggers your migraine and try avoiding them.
    • Stay hydrated. Drink plenty of fluids.
    • Learn relaxation skills, as they help reduce stress.

    Patients Concern

    Disease/Condition Glossary

    Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. A migraine headache is preceded by warning symptoms, one or two days before the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability, and neck stiffness. Symptoms of migraine include throbbing pain in one area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light.

    FAQs

    Caffeine+ergotamine+paracetamol+prochlorperazine is used to treat and prevent migraine. It is used to relieve the symptoms at the first sign of a migraine attack and to prevent the worsening of the attack.

    Caffeine+ergotamine+paracetamol+prochlorperazine contains Ergotamine, caffeine, prochlorperazine, and paracetamol. Ergotamine works by narrowing the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Caffeine enhances the vasoconstrictive effect (narrowing of blood vessels). Prochlorperazine prevents nausea and vomiting associated with migraine by modifying the effects of neurotransmitters. Paracetamol blocks the release of prostaglandins that cause pain.

    Dry mouth could be a side-effect of Caffeine+ergotamine+paracetamol+prochlorperazine. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

    Orthostatic hypotension could be a side-effect of Caffeine+ergotamine+paracetamol+prochlorperazine. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better.

    Do not discontinue Caffeine+ergotamine+paracetamol+prochlorperazine without consulting your doctor as it could lead to recurring or worsening of symptoms. To treat your condition effectually, continue taking Caffeine+ergotamine+paracetamol+prochlorperazine for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Caffeine+ergotamine+paracetamol+prochlorperazine.

    Do not take Caffeine+ergotamine+paracetamol+prochlorperazine along with antibiotics (clarithromycin, erythromycin, troleandomycin), antifungal (itraconazole, ketoconazole) and anti-HIV medicines (indinavir, nelfinavir, ritonavir). Caffeine+ergotamine+paracetamol+prochlorperazine contains ergotamine and caffeine, which, when taken along with these drugs, could lead to unpleasant side effects such as poor blood flow to the hands, feet, or brain.

    Caffeine+ergotamine+paracetamol+prochlorperazine may cause constipation. Eat high-fibre foods and drink plenty of fluids if you experience constipation. Talk to your doctor if the condition persists or worsens.

    When used responsibly and under medical guidance, Caffeine+ergotamine+paracetamol+prochlorperazine can be a highly effective treatment option. However, the long-term side effects are not well established. If you experience difficulties or concerns, consult your doctor promptly to discuss appropriate measures.

    No, Caffeine+ergotamine+paracetamol+prochlorperazine is not a blood thinner. It is a medication used to treat migraine headaches and contains a combination of ergotamine, caffeine, paracetamol, and prochlorperazine.

    No, taking a higher-than-recommended dose may not be more effective; instead, it may increase the risk of serious side effects and toxicity. Therefore, follow your doctor’s instructions and please consult your doctor. If you are experiencing increased severity of migraine attacks, which are not relieved by the recommended dose of this medicine, please consult your doctor for re-evaluation.

    Yes, Caffeine+ergotamine+paracetamol+prochlorperazine can expire. Please check the expiration date on the medicine pack. Do not use the Caffeine+ergotamine+paracetamol+prochlorperazine after the expiry date.

    A migraine is a severe headache that causes throbbing, pulsing pain on one side of the head. The headache phase usually lasts at least four hours, but it can also last for days.

    Migraine attacks can be triggered by various factors, including hormonal changes (especially around menstruation), stress, lack of sleep or too much sleep, certain foods and drinks like alcohol, caffeine, aged cheeses, bright lights, loud noises, strong smells, weather changes, dehydration, and sudden physical exertion. However, each person may have unique triggers that vary depending on their sensitivity.

    The common side effects of Caffeine+ergotamine+paracetamol+prochlorperazine are stomach upset, dizziness, dry mouth, constipation, and insomnia (trouble sleeping). Please consult your doctor if any of these side effects persist or worsen.

    Available Medicines for

    Caffeine+ergotamine+prochlorperazine+paracetamol

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