Calcium Orotate+cholecalciferol
About Calcium Orotate+cholecalciferol
Calcium Orotate+cholecalciferol is used to treat low calcium levels in conditions like Vitamin D deficiency, osteoporosis, hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels).
Calcium Orotate+cholecalciferol consists of calcium orotate and vitamin D3 (cholecalciferol), which help maintain blood calcium and phosphorus levels and support bone mineralisation.
Take Calcium Orotate+cholecalciferol as advised by your doctor. Sometimes, it may cause side effects like constipation and stomach upset. These side effects do not require medical attention and gradually resolve over time.
Do not take Calcium Orotate+cholecalciferol if you are allergic to any ingredient in it. Pregnant or breastfeeding women should consult their doctor before taking Calcium Orotate+cholecalciferol. Do not use Calcium Orotate+cholecalciferol if you have kidney problems/stones or have a high vitamin D level in your blood.
Uses of Calcium Orotate+cholecalciferol
Medicinal Benefits
When used as advised, Calcium Orotate+cholecalciferol may offer the following benefits:
For Vitamin D deficiency:
- Increases total vitamin D levels and treats vitamin D insufficiency.
- Increases bone mineral density and fortifies teeth and bones.
- Relieves deficiency-related bone pain, muscle pains, and weakness.
- Reduces the chance of bone fractures, particularly in older people.
For Osteoporosis:
- Reduces bone loss and increases bone mineral density
- Lowers the chance of fragility fractures, particularly those of the wrist, hip, and spine.
- Reduces osteoporosis-related muscular weakness and bone discomfort.
- Reduces the incidence of falls in elderly patients by promoting normal muscle strength.
For Osteomalacia:
- Decreases the chance of bone fractures and pseudofractures and gradually improves bone softness and abnormalities.
- Promotes healthy muscular movement and function.
- Helps with overall skeletal recovery when taken regularly.
For Tetany:
- Relieves tetany-related muscular stiffness, cramps, and spasms.
- Keeps calcium levels steady, helping prevent recurring tetany episodes.
- Promotes healthy muscle and nerve function
- Beneficial for long-term care once acute tetany is under control.
Directions for Use
- Take Calcium Orotate+cholecalciferol with or without food, or as advised by a doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Calcium Orotate+cholecalciferol
- Constipation
- Stomach upset
- Nausea
- Vomiting
- Loss of appetite
Medicines Containing this Salt
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Drug Warnings
- Do not take Calcium Orotate+cholecalciferol if you're allergic to any ingredient in it.
- Calcium Orotate+cholecalciferol is not recommended if you have hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).
- Consult your doctor if you are pregnant or breastfeeding.
- Calcium Orotate+cholecalciferol should be used with caution in children and only if recommended by a doctor.
- Inform your doctor before taking Calcium Orotate+cholecalciferol if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance.
Drug Interactions
Drug-Drug Interactions: Taking Calcium Orotate+cholecalciferol with the following medications may cause adverse reactions.
- Antibiotic (tetracycline, doxycycline)
• Potential effect: May reduce the effectiveness of antibiotics. - Water pills (hydrochlorothiazide)
• Potential effect: May cause increased risk of hypercalcemia (elevated calcium levels). - Medicines used to treat irregular heartbeat (digoxin)
• Potential effect: May increase the risk of irregular heartbeat. - Drugs treating bone loss (alendronate)
• Potential effect: May reduce the absorption of Calcium Orotate+cholecalciferol. - Thyroid hormone (levothyroxine)
• Potential effect: May reduce the absorption of other drugs. - Fits medicines (phenobarbital, phenytoin)
• Potential effect: May reduce the effectiveness of Vitamin D - Other Vitamin D supplements (Doxercalciferol, ergocalciferol)
• Potential effect: May cause elevated risk of vitamin D toxicity.
Drug-Food Interactions: Avoid or reduce caffeine, soft drinks, and alcohol, as they may inhibit calcium absorption.
Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Calcium Orotate+cholecalciferol, as it may worsen your condition or cause complications.
- Heart problems
- Malabsorption
- Kidney disease
- High calcium levels
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionDrinking alcohol can affect calcium absorption; hence, it is advised to limit alcohol intake while using Calcium Orotate+cholecalciferol.
Pregnancy
consult your doctorInform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Calcium Orotate+cholecalciferol.
Breast Feeding
consult your doctorInform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Calcium Orotate+cholecalciferol.
Driving
safe if prescribedCalcium Orotate+cholecalciferol does not impact your ability to drive or operate machinery.
Liver
cautionLet your doctor know if you have any history of liver diseases before taking Calcium Orotate+cholecalciferol. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.
Kidney
cautionSeek a doctor's advice before starting Calcium Orotate+cholecalciferol if you have kidney diseases like kidney stones or are undergoing dialysis. Cholecalciferol in Calcium Orotate+cholecalciferol increases inorganic phosphate levels in serum; hence, caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).
Children
cautionCalcium Orotate+cholecalciferol should be used with caution in children and only if recommended by a doctor.
Habit Forming
Diet & Lifestyle Advise
Healthy eating habits:
- Add foods high in calcium, such as milk, curd, paneer, cheese, ragi, sesame seeds, and almonds.
- Make sure you get enough vitamin D from foods like eggs, salmon, fortified milk, and mushrooms.
- To promote bone health, consume meals high in protein (dal, legumes, eggs, lean meat).
- To improve vitamin D synthesis, spend 15 to 20 minutes in the morning in the sun.
- Reduce your intake of carbonated drinks, salt, and caffeine because they accelerate the loss of calcium.
Lifestyle modifications:
- To strengthen your bones, engage in weight-bearing and strength-building activities such as yoga, stair climbing, and walking.
- To reduce bone stress and fracture risk, maintain a healthy body weight.
- Steer clear of alcohol and tobacco since they weaken bones and decrease the absorption of calcium.
- Wearing appropriate footwear and maintaining well-lit living areas can help prevent falls and injuries.
- To promote bone growth and general health, make sure you get enough sleep.
Patients Concern
Disease/Condition Glossary
Osteoporosis: Osteoporosis is a bone disease that weakens and makes bones brittle by decreasing bone density. As bones become less dense, they weaken and are more likely to break. Fracture is a serious complication of osteoporosis, particularly in older patients. Women are much more likely to develop osteoporosis than men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, and a bone that breaks much more easily than expected.
Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and soft, weak bones that can lead to bone deformities.
Tetany: A disease condition due to low levels of calcium (hypocalcemia) in the body that causes cramps and spasms in the hands, feet, and larynx (voice box).
Hypoparathyroidism: It is a disease characterised by low levels of parathyroid hormone. This can cause low calcium levels and trigger tetany.
FAQs
Calcium Orotate+cholecalciferol is used to treat low blood calcium levels. It effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). It can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Calcium Orotate+cholecalciferol is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.
Calcium Orotate+cholecalciferol is a combination of two medicines: Calcium orotate (mineral) and Cholecalciferol (Vitamin D3). Calcium orotate helps build and maintain bones. Cholecalciferol helps your body absorb Calcium orotate and supports the muscles needed to avoid falls.
Calcium Orotate+cholecalciferol can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Calcium Orotate+cholecalciferol as a daily supplement if you have a history of kidney problems or kidney stones.
Cholecalciferol in Calcium Orotate+cholecalciferol can increase inorganic phosphate levels in serum; hence, it should be cautiously used in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition). It is advised to follow a low-phosphate diet to control serum phosphorus levels in dialysis patients.
Calcium Orotate+cholecalciferol is used to increase low levels of calcium in the body. Hence, it is not advised to use Calcium Orotate+cholecalciferol if you have hypercalcemia since it causes an overdose of calcium, leading to kidney stones and other effects.
Calcium Orotate+cholecalciferol may cause side effects like constipation and stomach upset. These side effects do not require medical attention and gradually resolve over time.
