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About CEFOPERAZONE SODIUM+SULBACTAM

CEFOPERAZONE SODIUM+SULBACTAM belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract infection, urinary tract infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin and soft tissue infections, abdominal infections, bone and joint infections, genital tract infections, and endometritis (infection in the uterus).

CEFOPERAZONE SODIUM+SULBACTAM contains Cefoperazone sodium (cephalosporin antibiotic) and Sulbactam (beta-lactamase inhibitor). Cefoperazone sodium works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby killing the bacteria. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Cefoperazone sodium against the bacteria. Together, CEFOPERAZONE SODIUM+SULBACTAM helps treat bacterial infections.

CEFOPERAZONE SODIUM+SULBACTAM will be administered by a healthcare professional; do not self-administer. In some cases, CEFOPERAZONE SODIUM+SULBACTAM may cause diarrhoea, nausea, vomiting, headache, rash, and injection site reactions. Most of these side effects of CEFOPERAZONE SODIUM+SULBACTAM do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting CEFOPERAZONE SODIUM+SULBACTAM, please inform your doctor if you have any allergy to any antibiotic, kidney or liver problems. Consult your doctor before taking CEFOPERAZONE SODIUM+SULBACTAM if you are pregnant, planning for pregnancy, or breastfeeding. Avoid alcohol consumption while taking CEFOPERAZONE SODIUM+SULBACTAM to prevent unpleasant side effects. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of CEFOPERAZONE SODIUM+SULBACTAM

Bacterial infections

Medicinal Benefits

CEFOPERAZONE SODIUM+SULBACTAM belongs to the group of medicines called antibiotics used to treat various bacterial infections. CEFOPERAZONE SODIUM+SULBACTAM is a combination of two antibiotics: Cefoperazone sodium (cephalosporin antibiotic) and Sulbactam (beta-lactamase inhibitor). Cefoperazone sodium works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby killing the bacteria. On the other hand, Sulbactam works by decreasing bacterial resistance and enhancing the activity of Cefoperazone sodium against the bacteria. Together, CEFOPERAZONE SODIUM+SULBACTAM helps treat bacterial infections such as respiratory tract infection, urinary tract infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin and soft tissue infections, abdominal infections, bone and joint infections, genital tract infections, and endometritis (infection in the uterus).

Directions for Use

CEFOPERAZONE SODIUM+SULBACTAM will be administered by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CEFOPERAZONE SODIUM+SULBACTAM

  • Diarrhoea
  • Nausea
  • Vomiting
  • Headache
  • Rash
  • Injection site reactions

In-Depth Precautions and Warning

Drug Warnings

Do not take CEFOPERAZONE SODIUM+SULBACTAM if you are allergic to any of its components. Notify your doctor immediately if you experience any allergic reactions after taking CEFOPERAZONE SODIUM+SULBACTAM. Avoid alcohol consumption while taking CEFOPERAZONE SODIUM+SULBACTAM to prevent unpleasant side effects. Consult your doctor if you are pregnant or breastfeeding. Inform your doctor about all the medicines you take and your health condition to rule out any unpleasant side effects.

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: Avoid the consumption of alcohol or alcoholic beverages.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the colon's lining), hypoprothrombinaemia (decreased prothrombin production), dialysis, and kidney or liver dysfunction.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    Avoid consuming alcohol while taking CEFOPERAZONE SODIUM+SULBACTAM as it may cause flushing, sweating, headache and tachycardia.

  • Safety Warning

    Pregnancy

    caution

    If you are pregnant, please consult your doctor; your doctor will prescribe CEFOPERAZONE SODIUM+SULBACTAM only if the benefits outweigh the risks.

  • Safety Warning

    Breast Feeding

    caution

    CEFOPERAZONE SODIUM+SULBACTAM may pass into breastmilk. Therefore, CEFOPERAZONE SODIUM+SULBACTAM should be administered with caution in breastfeeding mothers.

  • Safety Warning

    Driving

    safe if prescribed

    CEFOPERAZONE SODIUM+SULBACTAM is unlikely to affect your ability to drive.

  • Safety Warning

    Liver

    caution

    Dose adjustment may be needed. Please consult your doctor before taking CEFOPERAZONE SODIUM+SULBACTAM if you have liver impairment/liver disease.

  • Safety Warning

    Kidney

    caution

    Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking CEFOPERAZONE SODIUM+SULBACTAM.

  • Safety Warning

    Children

    safe if prescribed

    CEFOPERAZONE SODIUM+SULBACTAM is safe to be used in children if recommended by a doctor. The dose may vary depending upon the child's weight.

Habit Forming

No

Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of CEFOPERAZONE SODIUM+SULBACTAM to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid intake of alcoholic beverages with CEFOPERAZONE SODIUM+SULBACTAM as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid CEFOPERAZONE SODIUM+SULBACTAM in fighting off infections.

Special Advise

CEFOPERAZONE SODIUM+SULBACTAM may cause a false-positive test for glucose in the urine with Benedict's or Fehling's solution. Therefore, inform the person doing the tests that you are taking CEFOPERAZONE SODIUM+SULBACTAM.

Patients Concern

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

FAQs

How does CEFOPERAZONE SODIUM+SULBACTAM work?

CEFOPERAZONE SODIUM+SULBACTAM contains Cefoperazone sodium and Sulbactam. Cefoperazone sodium works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby killing the bacteria. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Cefoperazone sodium against the bacteria. Together, CEFOPERAZONE SODIUM+SULBACTAM helps to treat bacterial infections.

What if I do not get better after using CEFOPERAZONE SODIUM+SULBACTAM?

Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor.

How long does CEFOPERAZONE SODIUM+SULBACTAM take to work?

Usually, CEFOPERAZONE SODIUM+SULBACTAM starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better.

Does CEFOPERAZONE SODIUM+SULBACTAM cause diarrhoea?

CEFOPERAZONE SODIUM+SULBACTAM may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking CEFOPERAZONE SODIUM+SULBACTAM and consult your doctor. Do not take anti-diarrheal medicine on your own.

Available Medicines for

CEFOPERAZONE SODIUM+SULBACTAM