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About CEFTAZIDIME+TAZOBACTAM

CEFTAZIDIME+TAZOBACTAM belongs to a class of medication called cephalosporin antibiotics. It is used to treat various bacterial infections in the body. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.

CEFTAZIDIME+TAZOBACTAM contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Tazobactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, CEFTAZIDIME+TAZOBACTAM helps to treat bacterial infections.

Sometimes, you may experience redness and swelling at the injection site, headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, and muscle spasms. Most of these side effects of CEFTAZIDIME+TAZOBACTAM do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking CEFTAZIDIME+TAZOBACTAM, tell your doctor if you are pregnant or breastfeeding. Inform your doctor if you are allergic to any foods or medications. Drive with caution since CEFTAZIDIME+TAZOBACTAM may cause dizziness. Before taking CEFTAZIDIME+TAZOBACTAM, inform your doctor about your medical history and other medications you are currently taking in order to rule out any potential negative effects.

Uses of CEFTAZIDIME+TAZOBACTAM

Bacterial infections

Medicinal Benefits

CEFTAZIDIME+TAZOBACTAM contains Ceftazidime and Tazobactam. Ceftazidime works by interfering with the production of the bacterial cell wall (a protective covering required for survival). Tazobactam reduces bacterial resistance and increases the action of Ceftazidime against bacteria. Together, they aid in the treatment of bacterial infections, including serious, life-threatening infections due to gram-positive bacteria. 

Directions for Use

CEFTAZIDIME+TAZOBACTAM will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CEFTAZIDIME+TAZOBACTAM

  • Redness and swelling on the injection site

  • Headache

  • Dizziness

  • Nausea

  • Vomiting

  • Diarrhea

  • Abdominal pain

  • Muscle spam

  • Elevated liver enzymes

In-Depth Precautions and Warning

Drug Warnings

Before taking the CEFTAZIDIME+TAZOBACTAM, inform your doctor about all your medical conditions, sensitivities, and all medications (including herbals and supplements) you are using. If you are pregnant or breastfeeding, inform your doctor before taking CEFTAZIDIME+TAZOBACTAM. You are recommended to complete the full course of CEFTAZIDIME+TAZOBACTAM as your doctor prescribes for effective results. CEFTAZIDIME+TAZOBACTAM should not be administered if you are currently on any vaccinations or are scheduled for the same. CEFTAZIDIME+TAZOBACTAM should be used with caution in those with Clostridium difficile-associated diarrhoea. Drive only if you are alert, as CEFTAZIDIME+TAZOBACTAM may cause dizziness.

Drug Interactions

Drug-Drug Interactions: CEFTAZIDIME+TAZOBACTAM may interact with certain vaccinations (e.g. BCG vaccine, cholera vaccine, typhoid vaccine) and immunosuppressive medications (e.g. mycophenolate mofetil).

Drug-Food Interactions: Alcohol consumption should be avoided.

Drug-Disease Interactions: CEFTAZIDIME+TAZOBACTAM may interact with certain disease conditions, including colitis (inflammation in your colon), renal dysfunction, renal impairment, dialysis, liver disease, and seizure disorders. So, inform your doctor about your medical conditions before taking CEFTAZIDIME+TAZOBACTAM.

Drug-Drug Interactions Checker List:

  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE
  • MYCOPHENOLATE MOFETIL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      The interaction of CEFTAZIDIME+TAZOBACTAM with alcohol is unknown. However, it is advisable not to take or limit alcohol as a precautionary measure.

    • Safety Warning

      Pregnancy

      caution

      The safety of CEFTAZIDIME+TAZOBACTAM in pregnant women is unknown. Therefore, please inform your doctor; your doctor will weigh the benefits and potential risks before prescribing this medicine.

    • Safety Warning

      Breast Feeding

      caution

      Consult the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medicine to the mother.

    • Safety Warning

      Driving

      caution

      CEFTAZIDIME+TAZOBACTAM may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking CEFTAZIDIME+TAZOBACTAM.

    • Safety Warning

      Liver

      caution

      Take CEFTAZIDIME+TAZOBACTAM with caution, especially if you have a history of liver diseases. Inform your doctor before receiving the CEFTAZIDIME+TAZOBACTAM if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Kidney

      caution

      Take CEFTAZIDIME+TAZOBACTAM with caution, especially if you have a history of kidney diseases. Inform your doctor before receiving the CEFTAZIDIME+TAZOBACTAM if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Children

      caution

      Limited information is available regarding the usage of CEFTAZIDIME+TAZOBACTAM in children, so please consult a doctor if you have any concerns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • It would be best to take probiotics after taking the full course of CEFTAZIDIME+TAZOBACTAM to restore some healthy intestinal bacteria that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
    • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after an antibiotic course. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
    • Avoid taking much calcium-enriched foods and drinks as it might affect the working of CEFTAZIDIME+TAZOBACTAM.
    • Avoid intake of alcoholic beverages with CEFTAZIDIME+TAZOBACTAM as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the CEFTAZIDIME+TAZOBACTAM in fighting off infections.

    Patients Concern

    Disease/Condition Glossary

    Bacterial Infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue.

    FAQs

    How does CEFTAZIDIME+TAZOBACTAM work?

    Ceftazidime and Tazobactam are both present in CEFTAZIDIME+TAZOBACTAM. Ceftazidime works by preventing the production of the bacterial cell wall (a protective covering required for survival). Tazobactam reduces bacterial resistance while increasing the efficacy of Ceftazidime against bacteria. Together, CEFTAZIDIME+TAZOBACTAM aids in the treatment of bacterial illnesses.

    Does CEFTAZIDIME+TAZOBACTAM affect laboratory test results?

    CEFTAZIDIME+TAZOBACTAM may Increase liver enzymes. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking CEFTAZIDIME+TAZOBACTAM.

    Does CEFTAZIDIME+TAZOBACTAM cause diarrhoea?

    CEFTAZIDIME+TAZOBACTAM may cause diarrhoea as a common side effect. However, if the condition persists or worsens, consult a doctor immediately.

    Is it ideal to take vaccination while on CEFTAZIDIME+TAZOBACTAM therapy?

    If you are being treated with CEFTAZIDIME+TAZOBACTAM or have been treated within the last three days, you should talk to your doctor before taking the vaccine. Antibiotics like CEFTAZIDIME+TAZOBACTAM can reduce the activity of the vaccine.

    Available Medicines for

    CEFTAZIDIME+TAZOBACTAM