Cetirizine+diethylcarbamazine
About Cetirizine+diethylcarbamazine
Cetirizine+diethylcarbamazine is an oral prescription medicine used to treat parasitic infections, including lymphatic filariasis and tropical pulmonary eosinophilia. It is specifically designed to target the parasitic worms causing the infection while simultaneously relieving the allergic reactions, wheezing, and coughing that can occur. This dual action helps clear the underlying illness and ease your symptoms at the same time.
You should take this medication exactly as prescribed by your healthcare provider, usually once or twice daily, and try to take it at the same time each day to maintain steady levels in your body. It can be taken with or without food, though taking it after a meal can help reduce the risk of stomach upset. Your doctor may prescribe a course lasting several days to a few weeks, and it is important to complete the entire course even if your symptoms improve earlier. Drinking plenty of fluids and maintaining excellent hygiene can significantly support your body's recovery during treatment.
While taking Cetirizine+diethylcarbamazine, you may experience mild side effects such as sleepiness, dry mouth, or a mild headache. However, you must seek immediate medical attention if you notice signs of a severe allergic reaction, such as swelling of your face or throat, or if you experience a high fever and severe muscle pain.
Before starting this medication, tell your doctor if you have kidney problems, heart conditions, or a history of seizures. Do not take this medicine if you have a known allergy to any of its active components.
This medicine can interact with alcohol and medications like sleeping pills or sedatives, which can increase drowsiness and make you feel unsteady. Pregnant or breastfeeding women, as well as elderly individuals, should consult their doctor before starting this treatment to ensure it is safe for them.
Uses of Cetirizine+diethylcarbamazine
• Treatment of Bancroft's filariasis: Cetirizine+diethylcarbamazine is effective in killing Wuchereria bancrofti filarial worms and reducing allergic symptoms associated with the infection.
• Treatment of Eosinophilic lung: Cetirizine+diethylcarbamazine helps destroy filarial worms trapped in lung tissue and reduces eosinophil-mediated lung inflammation.
• Treatment of Loiasis: Cetirizine+diethylcarbamazine is used to kill Loa loa worms and helps relieve allergic symptoms caused by the parasitic infection.
• Treatment of River blindness (onchocerciasis): Although Cetirizine+diethylcarbamazine is rarely used to treat river blindness due to the risk of severe adverse reactions, it may be used under medical supervision in certain cases.
Medicinal Benefits
Cetirizine+diethylcarbamazine helps treat certain parasitic infections while relieving the allergic symptoms they can cause. By reducing itching, swelling, and other discomforts alongside treating the underlying infection, it helps you feel better and recover more comfortably.
Benefits may include:
- Helps treat certain parasitic worm infections effectively.
- Reduces itching, skin irritation, and allergic reactions associated with the infection.
- Improves comfort by relieving swelling and inflammation caused by the body's response to parasites.
- Supports recovery by treating the underlying infection and its symptoms together.
- Promotes better breathing by helping relieve respiratory symptoms associated with certain parasitic infections.
Directions for Use
- Swallow the tablet whole with a glass of water. Do not crush, chew, or break it.
- You can take this medicine with or without food, but taking it after a meal may help prevent an upset stomach.
- Always follow your doctor's exact instructions regarding dosage and duration. Complete the full prescribed course, even if you start feeling better.
Storage
Side Effects of Cetirizine+diethylcarbamazine
Common Side Effects (Usually mild):
- Sleepiness or drowsiness
- Dry mouth
- Mild headache
- Nausea or upset stomach
- Dizziness or fatigue
Serious Side Effects (Call a doctor right away):
- Severe allergic reactions (such as sudden swelling of the face, lips, tongue, or throat, or difficulty breathing)
- High fever, severe joint pain, intense headache, or worsening rash shortly after starting treatment. These may be signs of a recognised reaction to dying parasites (sometimes called a Mazzotti-like reaction).
- Seizures or fits
- Vision changes or eye pain
Medicines Containing this Salt
View AllDrug Warnings
- Check your alertness: Avoid driving, operating heavy machinery, or doing activities that require full attention until you know how this medicine affects you. It may cause drowsiness in some people.
- Know what reactions to expect: You may develop a mild fever, muscle aches, itching, or body pain during the first few days of treatment as the parasites die. These reactions are usually temporary, but seek medical help immediately if your symptoms become severe.
- Inspect the medicine before use: Check that the packaging is intact and make sure the medicine has not expired before taking it. Do not use it if the packaging is damaged or the expiry date has passed.
- Inform your healthcare provider before procedures: Tell your doctor, surgeon, or dentist that you are taking this medicine before any medical or dental procedure. This helps them plan your treatment safely.
- Complete the full course: Keep taking this medicine for the full duration prescribed, even if you start feeling better. Finishing the entire course helps clear the infection completely and reduces the chance of it returning.
Drug Interactions
- Medicines That Cause Drowsiness (e.g., zolpidem, alprazolam, clonazepam, cyclobenzaprine): Taking these medicines alongside Cetirizine+diethylcarbamazine may increase the risk of drowsiness, dizziness, and impaired alertness.
- Medicines That May Affect Kidney Function (e.g., cyclosporine, tacrolimus, ibuprofen, gentamicin): These medicines may affect how Cetirizine+diethylcarbamazine is removed from the body and may require closer monitoring.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Cetirizine+diethylcarbamazine as it may increase adverse effects. Please consult a doctor before consuming alcohol with Cetirizine+diethylcarbamazine.
Pregnancy
cautionPlease consult a doctor if you are pregnant, as Cetirizine+diethylcarbamazine is for pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionPlease consult a doctor if you are breastfeeding, as Cetirizine+diethylcarbamazine may be excreted in human milk. It is given to breastfeeding mothers only if the doctor believes the benefits outweigh the risks.
Driving
cautionCetirizine+diethylcarbamazine may cause drowsiness or dizziness in some people. Therefore, drive only if you are alert after taking Cetirizine+diethylcarbamazine.
Liver
cautionTake Cetirizine+diethylcarbamazine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Cetirizine+diethylcarbamazine with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Patients with severe kidney problems should avoid taking Cetirizine+diethylcarbamazine.
Children
cautionCetirizine+diethylcarbamazine is not recommended for children under 6 years of age, as its safety and effectiveness have not been established. However, for children above 6 years, Cetirizine+diethylcarbamazine should be used with caution if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Stay well hydrated: Drink plenty of water throughout the day to help your kidneys remove waste products released as the parasites are cleared from your body.
- Maintain good hygiene: Wash your hands regularly and keep yourself and your surroundings clean to help reduce the risk of reinfection.
- Avoid alcohol: Do not drink alcohol while taking this medicine, as it can increase drowsiness and dizziness.
- Choose light meals: Eat small, easy-to-digest meals if you experience nausea or stomach upset, especially during the first few days of treatment.
- Prevent mosquito bites: If you are being treated for filariasis, use mosquito nets and insect repellents to help prevent mosquito bites and reduce the spread of the infection.
Special Advise
- If you are about to take an allergy skin test, inform your doctor that you are taking Cetirizine+diethylcarbamazine as you may be advised to stop taking Cetirizine+diethylcarbamazine for 3 days before the test.
- Regular blood tests are recommended while taking Cetirizine+diethylcarbamazine to monitor blood count and liver functioning.
- Regular eye checkups to monitor loss of vision, night blindness, or tunnel vision.
Patients Concern
Disease/Condition Glossary
Bancroft’s Filariasis: It is also known as elephantiasis and is caused by thread-like worms that live inside the human lymphatic system. The lymphatic system of the body consists of fluid and is responsible for fighting infections. This disease is transmitted from person to person through the bite of infected mosquitoes. Common symptoms include swelling in the legs, arms, breasts, or genitals. The legs are most commonly affected, while skin may also be affected, causing dry, ulcerated, thick, pitted, or darker than normal skin.
Eosinophilic lung: This is a disease related to lung problems in which white blood cells in the body increase. White blood cells are responsible for fighting allergic reactions and certain infections. Some of the symptoms of this disease include cough, chest pain, tightness, increased mucus, rapid breathing, bloody mucus, and shortness of breath.
Loiasis: It is also called 'African eye worm', which is an infectious parasitic disease transmitted to humans by the bite of the Chrysops fly species. A person infected with this disease may face itchy, non-painful swellings in their body. Sometimes, a person may see worms crawling under their skin or across the surface of the eye.
River blindness: It is caused by a parasitic worm and is transmitted through repeated bites by black flies near rivers and streams. If not treated, then it may even cause visual impairment and sometimes blindness.
FAQs
Cetirizine+diethylcarbamazine is used to treat certain parasitic infections, such as Bancroft's filariasis, Eosinophilic lung disease, Loiasis, and River blindness.
Cetirizine+diethylcarbamazine contains Cetirizine and Diethylcarbamazine used to treat certain parasitic infections such as Bancroft's filariasis, Eosinophilic lung, Loiasis, and River blindness. Cetirizine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from allergic symptoms. Diethylcarbamazine is an anthelmintic (antiparasitic) that works by causing paralysis of the worms by reducing their muscular activity.
No, Cetirizine+diethylcarbamazine is not used to treat tapeworm or pinworm infections. However, please consult a doctor if you have a tapeworm or pinworm infection so that the appropriate medication can be prescribed.
Cetirizine+diethylcarbamazine may cause vision problems, such as night blindness, tunnel vision, or loss of vision, if used for a prolonged period. Therefore, regular eye check-ups are recommended while taking Cetirizine+diethylcarbamazine.
Cetirizine+diethylcarbamazine should be used with caution in patients experiencing seizures, as it may trigger recurring seizures. Therefore, please inform your doctor if you have or are at risk of having fits.
You are not recommended to take Cetirizine+diethylcarbamazine with diphenhydramine (an antihistamine) as it may increase adverse effects such as drowsiness, dizziness and difficulty concentrating. However, please consult a doctor before taking Cetirizine+diethylcarbamazine with other medicines.
No. Continue taking Cetirizine+diethylcarbamazine for the full duration prescribed by your doctor, even if your symptoms improve before the course is complete. Stopping treatment early may not completely clear the infection and could increase the risk of the infection persisting or recurring. If you have concerns about continuing the medicine, consult your doctor before stopping it.
This medicine can cause drowsiness and dizziness in some people. It is safest to avoid driving or operating machinery until you know how it affects you. Talk to your doctor if you experience persistent sleepiness or dizziness.
You should avoid alcohol while on this medication, as it can worsen side effects like sleepiness and dizziness. Talk to your doctor if you have any questions about alcohol use while taking this medicine.
A mild fever can sometimes happen as the medicine works to clear parasites from your system. This is usually temporary. However, if the fever is high, accompanied by severe joint pain, severe headache, breathing difficulty, or other concerning symptoms, contact your doctor immediately.
This medicine is generally not recommended during pregnancy unless your doctor decides it is absolutely necessary. If you are pregnant or planning to become pregnant, inform your doctor before starting this medicine. Talk to your doctor if you have any concerns.
Yes. This medicine can be taken with or without food, as directed by your doctor. However, if it causes stomach upset or nausea, taking it after a meal may help reduce these symptoms. Try to take it at the same time each day. Talk to your doctor if you have any concerns.
Yes. Dry mouth is a common side effect of Cetirizine+diethylcarbamazine. Sipping water regularly, chewing sugar-free gum, or sucking on sugar-free lozenges may help relieve this symptom. If dry mouth is severe, persistent, or makes it difficult to eat or speak, consult your doctor.

