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About PARACETAMOL+PSEUDOEPHEDRINE+CHLORPHENIRAMINE

CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE belongs to the class of medication called 'cough and cold medications' primarily used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion or watery eyes. The common cold is a respiratory illness affecting the nose and throat. It is mostly caused by viruses known as 'rhinovirus'. The virus enters the body through the nose, mouth or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs or talks.

CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE is a combination medicine that contains Paracetamol (mild analgesic and antipyretic), Pseudoephedrine (decongestant), and Chlorpheniramine (antihistamine/antiallergic). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by blocking the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Pseudoephedrine is a decongestant that works by contracting and narrowing the small blood vessels of nasal passages and airways, relieving congestion or stuffiness in the nose. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling and nasal congestion.

Take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE as prescribed by your doctor. Your doctor will recommend how often you take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE based on your medical condition. Some people may experience nausea, sleepiness, allergic reaction, dizziness, headache, restlessness, nervousness and insomnia (difficulty sleeping). Most of these side effects of CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE or any other medicines, please tell your doctor. Please do not take more than the prescribed dose of CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE. If you are pregnant, it is advised to inform your doctor before using CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE. Do not use CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE in breastfeeding mothers without doctor’s advice as it may be excreted in breast milk and cause harm to the baby. CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE is not recommended for children below 4 years.

Uses of PARACETAMOL+PSEUDOEPHEDRINE+CHLORPHENIRAMINE

Common cold, Allergies

Medicinal Benefits

CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE belongs to the class of medication called 'cough and cold medications' primarily used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion or watery eyes. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by blocking the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Pseudoephedrine is a decongestant that works by contracting and narrowing the small blood vessels of nasal passages and airways, relieving congestion or stuffiness in the nose. Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling and nasal congestion.

Directions for Use

Tablet/capsule: Use CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE as prescribed by your doctor. Take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with or without food and swallow whole with a glass of water. Do not crush, chew, or break it. Oral Liquid syrup: Shake the bottle well before use. Check the label for directions and take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with or without food in doses as prescribed by a doctor with the help of a measuring cup.

Storage

Store in a cool and dry place away from sunlight

Side Effects of PARACETAMOL+PSEUDOEPHEDRINE+CHLORPHENIRAMINE

  • Nausea
  • Allergic reaction
  • Dizziness
  • Headache
  • Restlessness
  • Nervousness
  • Insomnia (difficulty in sleeping).

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE. Do not use CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE in breastfeeding mothers without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE is not recommended for children below 4 years. Please do not take more than the prescribed dose of CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE as it may cause liver damage and can be lethal.  If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE.

Drug Interactions

Drug-Drug Interactions: CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE may interact with antidepressants (duloxetine, escitalopram), sleeping agents (ramelteon), pain killers (ibuprofen), fits medicine (phenytoin, carbamazepine) and blood pressure-lowering pills (atenolol, propranolol).

Drug-Food Interactions: Avoid intake of CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. Avoid consumption of alcohol with CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE as it may increase the risk of liver damage and cause increased drowsiness, dizziness, and difficulty in concentrating.

Drug-Disease Interactions: If you have high blood pressure, diabetes, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, enlarged prostate gland, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE.

Drug-Drug Interactions Checker List:

  • DULOXETINE
  • ESCITALOPRAM
  • RAMELTEON
  • IBUPROFEN
  • PHENYTOIN
  • CARBAMAZEPINE
  • ATENOLOL
  • PROPRANOLOL
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE as it may increase the risk of liver damage and cause increased drowsiness, dizziness or difficulty concentrating. Please consult your doctor before consuming alcohol with CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE.

    • Safety Warning

      Pregnancy

      caution

      The safety of CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE in pregnant women is unknown. If you are pregnant, consult your doctor before taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE. Your doctor prescribes this medicine if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE may pass into breast milk and cause harm to your baby. Besides this, CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE may also slow milk production, so it is better to contact your doctor before taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE.

    • Safety Warning

      Driving

      caution

      CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE.

    • Safety Warning

      Liver

      caution

      CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE has paracetamol which may causes harm to the liver in doses more than the recommended dose. Take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE is not recommended for children below 4 years of age. However, please consult your doctor before giving CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE to children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Wash your hands with soap and water regularly to prevent the spread of germs.
    • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health.
    • Drink plenty of fluids to avoid dehydration.
    • Gargle with salt water for relief from sore throat.
    • Avoid alcohol consumption with CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE as it may cause tiredness, drowsiness, or lack of concentration.

    Special Advise

    • Do not give CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE to children below 4 years of age.
    • Do not take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE for longer than 7 days in a row (for adults) and 5 days (for the children above 4 years).
    • If you have allergic skin reactions like skin redness, rash that spreads and causes blistering and peeling, immediately contact a doctor.
    • Patients with glaucoma or benign prostatic hyperplasia (BPH) should use the medicine with caution, consult your doctor if you face any problems while using CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE.

    Patients Concern

    Disease/Condition Glossary

    Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected by having 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The common cold symptoms include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, unwell, and stuffy or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.

    Allergies: These occur when foreign allergy-causing agents (allergens) attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, and itchy/watery nose, throat and eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever etc.

    FAQs

    How does CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE work?

    CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE contains Paracetamol, Pseudoephedrine, and Chlorpheniramine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Pseudoephedrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from congestion and decreases the mucus production. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling and congestion or stiffness.

    Does CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE cause drowsiness?

    Yes, CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE may cause drowsiness. It is not necessary for everyone taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE to experience this side effect. Therefore, avoid driving or operate heavy machinery if you feel drowsy after taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE.

    Does CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE also relieve pain and fever?

    Yes, CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE contains paracetamol which acts as a mild pain killer (analgesic) and fever reducer (antipyretic). It works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.

    Can I take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with an antiallergic medicine (Cetirizine)?

    No, you are not recommended to take CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with Cetirizine as co-administration of these two medicines may increase sedation and cause drowsiness, dizziness and difficulty concentrating. However, please consult a doctor before taking CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE with other medicines.

    Can the use of CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE cause damage to liver?

    CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE contains Paracetamol. This medicine is known to produce harm to the liver, mainly in doses more than the recommended level. Also, avoid drinking alcohol while taking this CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE, as it may further increase your risk of liver damage. Use of this CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE should preferably be prevented in patients with underlying liver disease. Inform your doctor immediately if you observe any early signs and symptoms of liver damage. These symptoms may involve rash, fever, loss of appetite, vomiting, nausea, stomach pain, fatigue, yellow skin or eyes, dark urine and abnormal liver enzymes.

    Can CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE be used with MAO inhibitor?

    Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline and tranylcypromine.

    Available Medicines for

    CHLORPHENIRAMINE+PARACETAMOL+PSEUDOEPHEDRINE