Cholecalciferol+rosuvastatin
About Cholecalciferol+rosuvastatin
Cholecalciferol+rosuvastatin is a prescription medication used to manage high cholesterol levels and treat or prevent vitamin D deficiency in adults. It plays a key role in reducing the risk of heart attacks and strokes while simultaneously supporting bone and muscle health. By managing these two health factors together, this medication helps protect your long-term cardiovascular and skeletal wellness.
For this medication to work effectively, you must take it consistently every day, exactly as your doctor has prescribed. You can take this tablet with or without food, though taking it at the same time each day helps establish a regular routine. To get the best results, it is highly recommended to combine this treatment with a balanced, low-fat diet and regular physical activity.
While taking Cholecalciferol+rosuvastatin, some patients may experience mild side effects, such as temporary stomach upset, headaches, or mild muscle discomfort. However, you must contact your doctor immediately if you develop serious symptoms, including unexplained, severe muscle pain, unusual fatigue, or a yellowing of your skin or eyes.
Before starting this medication, talk to your doctor or pharmacist about your complete medical history. Do not take this if you have active liver disease, severe kidney problems, or if you are pregnant or breastfeeding, as it can cause harm to a developing baby.
This medication can interact with other substances, including warfarin, certain cholesterol-lowering medicines, antacids containing aluminium or magnesium, and heavy alcohol use, which may increase the risk of side effects or affect how well the medicine works. If you belong to specific patient groups, such as the elderly, always consult your healthcare provider to ensure this treatment is safe for your individual health status.
Uses of Cholecalciferol+rosuvastatin
Medicinal Benefits
Cholecalciferol+rosuvastatin provides comprehensive cardiovascular and bone health support by combining a cholesterol-lowering medicine with vitamin D supplementation. Its benefits include:
- Lowers Cholesterol Effectively: The rosuvastatin component reduces the production of cholesterol in the liver, helping lower LDL cholesterol and triglycerides while increasing protective HDL cholesterol.
- Protects Heart and Blood Vessels: By reducing cholesterol buildup inside the arteries, it helps lower the risk of heart attacks, strokes, and other cardiovascular complications over the long term.
- Supports Healthy Bones and Muscles: The cholecalciferol (vitamin D₃) component improves calcium absorption, helping maintain strong bones, healthy muscles, and overall skeletal health.
- Convenient Combination Therapy: Combining both medicines into a single tablet simplifies daily treatment, making it easier to follow your prescribed medication regimen consistently.
- Promotes Long-Term Health: Regular use, together with a healthy diet and lifestyle, helps protect both your cardiovascular system and your musculoskeletal health, supporting a healthier and more active life.
Directions for Use
- Take Cholecalciferol+rosuvastatin with or without food, or as advised by a doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Cholecalciferol+rosuvastatin
Common Side Effects (Usually mild)
- Headache
- Mild nausea or upset stomach
- Mild muscle pain or weakness
- Feeling unusually tired or dizzy
- Constipation or mild diarrhea
Serious Side Effects (Call a doctor right away)
- Severe, unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or dark-colored urine
- Yellowing of your skin or the whites of your eyes (signs of liver damage)
- Signs of a severe allergic reaction, such as swelling of the face, lips, tongue, or throat, severe skin rash, or difficulty breathing
- Severe upper stomach pain
Medicines Containing this Salt
View AllDrug Warnings
- Attend Regular Blood Tests: Always attend your scheduled appointments for blood tests so your doctor can regularly check your liver health and cholesterol levels.
- Check Before Starting New Medicines: Do not start any new prescription medicines, over-the-counter drugs, or herbal supplements without talking to your doctor or pharmacist first.
- Check Before Making Major Dietary Changes: Unlike some other statins, rosuvastatin is not significantly affected by grapefruit juice. However, continue following the dietary advice provided by your doctor and discuss any major dietary changes if you have concerns.
- Avoid Use During Pregnancy: Stop taking this medication and contact your doctor immediately if you suspect you have become pregnant.
- Do Not Share Your Medication: Never share this medication with anyone else, even if they have similar medical conditions or symptoms.
Drug Interactions
- Warfarin and other vitamin K antagonists: Rosuvastatin may increase the blood-thinning effect of warfarin, raising your INR and the risk of bleeding. Your doctor may monitor your INR more closely when starting, stopping, or changing the dose of this medicine.
- Antacids: Antacids containing aluminum or magnesium can reduce the absorption of this medication; they should be taken at least 2 hours apart.
- Other cholesterol medicines: Combining this with other lipid-lowering drugs may increase the risk of severe muscle side effects.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Cholecalciferol+rosuvastatin as it may increase the risk of liver damage. Please consult a doctor before consuming alcohol with Cholecalciferol+rosuvastatin.
Pregnancy
unsafeCholecalciferol+rosuvastatin is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause harm to the unborn baby. So, if you are pregnant or planning for pregnancy, please inform your doctor before taking Cholecalciferol+rosuvastatin.
Breast Feeding
unsafeAvoid breastfeeding while taking Cholecalciferol+rosuvastatin as it may be unsafe for the baby. However, please consult a doctor before taking Cholecalciferol+rosuvastatin.
Driving
cautionCholecalciferol+rosuvastatin usually does not affect your ability to drive or operate machinery. However, if you feel dizzy after taking Cholecalciferol+rosuvastatin, avoid driving or operating machinery.
Liver
cautionPlease consult a doctor if you have any liver disease. Cholecalciferol+rosuvastatin is usually not recommended in patients with liver disease.
Kidney
cautionTake Cholecalciferol+rosuvastatin with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required. Cholecalciferol+rosuvastatin is not recommended in patients with severe kidney problems.
Children
cautionCholecalciferol+rosuvastatin is not recommended for children below 6 years of age. However, Cholecalciferol+rosuvastatin should be used with caution in children above 6 years if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Follow a Heart-Healthy Diet: Focus on a heart-healthy diet low in saturated and trans fats, replacing them with whole grains, lean proteins, vegetables, and high-fibre foods.
- Include Calcium-Rich Foods: Incorporate calcium-rich foods like low-fat dairy products, leafy greens, and almonds into your meals to support the vitamin D action in your body.
- Exercise Regularly: Aim for at least 150 minutes of moderate aerobic exercise, such as brisk walking, swimming, or cycling, each week, as approved by your healthcare provider.
- Limit Alcohol Intake: Limit your alcohol intake, as combining alcohol with this medication can put extra stress on your liver.
- Avoid Smoking: Avoid smoking, as tobacco use damages blood vessels and significantly reduces the benefits of your cholesterol therapy.
Special Advise
- Regular blood tests are recommended while taking Cholecalciferol+rosuvastatin to monitor cholesterol levels in the blood and liver functioning.
- Regularly monitor blood sugar levels as Cholecalciferol+rosuvastatin may increase the risk of developing diabetes, especially in patients who are overweight, have high blood pressure, or have high levels of fats and sugars in the blood.
- Maintain a low-fat diet along with Cholecalciferol+rosuvastatin for effective results.
Patients Concern
Disease/Condition Glossary
High cholesterol: High cholesterol, also known as hyperlipidemia or dyslipidemia, occurs when there is an excess of unhealthy cholesterol in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol foods and drinks, and genetic factors are the primary causes of high cholesterol.
FAQs
Cholecalciferol+rosuvastatin is used to lower raised cholesterol levels. This reduces the risk of heart attack and stroke in future.
Cholecalciferol+rosuvastatin contains Rosuvastatin and Cholecalciferol. Rosuvastatin works by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. This thereby decreases the production of LDL (bad cholesterol) by the liver. Cholecalciferol relieves muscle pain caused by Rosuvastatin.
You are not recommended to take Cholecalciferol+rosuvastatin with fusidic acid as co-administration of these two medicines may lead to a severe muscle problem known as rhabdomyolysis (the breakdown of muscle tissue). Therefore, inform your doctor if you have taken fusidic acid in the last 7 days before taking the Cholecalciferol+rosuvastatin. You may be advised to stop taking Cholecalciferol+rosuvastatin if you need to take fusidic acid. However, please consult a doctor before taking Cholecalciferol+rosuvastatin with any other medicines.
Yes, Cholecalciferol+rosuvastatin may cause rhabdomyolysis (the breakdown of muscle tissue) and may lead to kidney failure in some patients. It is not necessary for everyone taking Cholecalciferol+rosuvastatin to experience this adverse effect. However, if you experience unexplained muscle pain, weakness or tenderness, especially along with fever, dark coloured urine or unusual tiredness, please consult your doctor immediately.
No, you are not recommended to stop taking Cholecalciferol+rosuvastatin without consulting your doctor, as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Cholecalciferol+rosuvastatin for as long as your doctor has prescribed it, and if you experience any difficulty while taking Cholecalciferol+rosuvastatin, please consult your doctor so that the dose may be gradually reduced.
No, Cholecalciferol+rosuvastatin and Rozavel are not the same. Rozavel contains Rosuvastatin, whereas Cholecalciferol+rosuvastatin contains both Rosuvastatin and Cholecalciferol.
No, Cholecalciferol+rosuvastatin is not a blood thinner. It contains Rosuvastatin and Cholecalciferol. Rosuvastatin is a statin that lowers cholesterol, and Cholecalciferol is Vitamin D3, used to support bone health.
Some people may experience common side effects of Cholecalciferol+rosuvastatin, such as nausea, headache, stomach pain, dizziness, weakness, muscle pain, or constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
The use of Cholecalciferol+rosuvastatin may increase the risk of developing diabetes because it contains Rosuvastatin, which can raise blood sugar levels, especially in patients already at risk. It is better to inform your doctor if you have a family history of diabetes, are overweight, or have high blood sugar levels to discuss the potential risks and benefits.
You may feel more tired while using Cholecalciferol+rosuvastatin, as weakness is a reported common side effect of Cholecalciferol+rosuvastatin, which can contribute to tiredness. If you experience persistent fatigue or other symptoms, it's best to consult your doctor for advice.
Cholecalciferol+rosuvastatin is not recommended for specific individuals, including pregnant or breastfeeding women and those with a history of allergy to any ingredients. People with liver or kidney problems and those taking certain medications should also exercise caution. Additionally, individuals with a history of muscle disorders or those who are sensitive to any of the ingredients should not take this medication. It's essential to consult your doctor or pharmacist before taking Cholecalciferol+rosuvastatin, especially if you have any underlying medical conditions or take other medications.
When taking Cholecalciferol+rosuvastatin, eat lots of fruits and vegetables, whole grains, lean proteins like fish and chicken, healthy fats like olive oil and avocados, and low-fat dairy products. Avoid fatty meats, full-fat dairy, fried foods, organ meats, shellfish, egg yolks, sugary foods and drinks, alcohol, and grapefruit. Following these dietary instructions can support your overall health, manage your condition, and potentially aid in recovery.
Inform your doctor if you have diabetes before taking Cholecalciferol+rosuvastatin, as it may elevate sugar levels. It is essential to take precautions to control sugar levels while taking this medication. Your doctor may need to closely monitor your blood sugar levels, adjust your diabetes treatment plan, or recommend lifestyle changes to help manage your sugar levels effectively.
No, this medication is not safe for use during pregnancy as it may cause harm to the developing baby. If you become pregnant or plan to become pregnant, stop taking the medication and talk to your doctor immediately.
If you experience unexplained, severe, or persistent muscle pain, tenderness, or weakness—especially if you also have a fever—contact your healthcare provider right away to rule out any serious muscle issues. Talk to your doctor.
It is highly recommended to limit or avoid alcohol while taking this medication. Heavy drinking can increase your risk of liver damage and worsen potential muscle-related side effects. Talk to your doctor about what is safe for you.
You can take this medication at any time of day, with or without food, as long as you take it at the same time every day to maintain steady levels in your body. Talk to your doctor or pharmacist to find the best schedule for your routine.
Yes, your doctor will schedule regular blood tests to monitor your cholesterol levels, vitamin D levels, and liver function to ensure the medication is working safely and effectively. Talk to your doctor about how often you need these tests.
Since this medicine already contains a clinical dose of vitamin D, taking additional vitamin D or calcium supplements without medical supervision could lead to excessively high levels in your body. Talk to your doctor or pharmacist before taking any new supplements.
If you miss a dose, take it as soon as you remember. However, if your next dose is less than 12 hours away, skip the missed dose and resume your normal daily routine. Do not double the dose. Talk to your doctor if you frequently miss doses.

