Cinitapride+rabeprazole
About Cinitapride+rabeprazole
Cinitapride+rabeprazole is a prescription medicine used to treat gastroesophageal reflux disease (GERD) and active indigestion. It works by reducing excessive stomach acid and improving the movement of food through your digestive system to relieve symptoms like heartburn and stomach fullness.
To achieve the best results, you must take this medicine consistently every day at the frequency recommended by your doctor. It is highly recommended to take this capsule on an empty stomach, typically 15 to 30 minutes before your morning meal. Incorporating lifestyle changes such as eating smaller, low-fat meals and avoiding lying down immediately after eating can greatly enhance the efficacy of this treatment.
While taking Cinitapride+rabeprazole, some patients may experience mild side effects, including mild headaches, dizziness, or diarrhoea. However, if you experience more serious issues such as severe watery diarrhoea, persistent stomach pain, or unusual muscle movements, you must contact your doctor immediately.
Talk to your doctor before starting this medication if you have a history of liver damage, kidney disease, or cardiac conditions. Do not take this if you have a known blockage in your stomach or intestines, internal bleeding in your digestive tract, or if you have previously experienced movement disorders caused by medications.
This medicine can interact with certain blood thinners, antifungal therapies, or alcohol, which can alter its effectiveness or increase the risk of side effects. Special patient groups, including pregnant women, breastfeeding mothers, and elderly individuals, should consult their healthcare provider before beginning treatment.
Uses of Cinitapride+rabeprazole
Medicinal Benefits
Cinitapride+rabeprazole helps reduce excess stomach acid while improving the movement of food through the digestive tract, providing effective relief from acid-related digestive symptoms. The combination offers the following benefits:
- Relieves acid reflux and heartburn: Rabeprazole reduces stomach acid production, helping relieve heartburn, acid regurgitation, and irritation of the food pipe.
- Improves stomach emptying: Cinitapride enhances the movement of food through the stomach and intestines, reducing bloating, fullness, and delayed gastric emptying.
- Reduces nausea and indigestion: By improving gastrointestinal motility, it helps relieve nausea, indigestion, and discomfort after meals.
- Promotes healing of acid-related damage: Lowering stomach acid allows inflamed or damaged tissues in the oesophagus and stomach to heal more effectively.
- Provides long-lasting symptom control: The combination addresses both excess acid production and impaired stomach motility, offering more comprehensive and sustained relief from gastroesophageal reflux disease (GERD) and related digestive disorders.
Directions for Use
- Take Cinitapride+rabeprazole on an empty stomach or as advised by the doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow Cinitapride+rabeprazole as a whole with a glass of water.
- Do not crush, open, or chew it.
Storage
Side Effects of Cinitapride+rabeprazole
Common Side Effects (Usually mild)
- Mild headache
- Dizziness or lightheadedness
- Mild diarrhoea or loose stools
- Dry mouth
- Nausea or slight stomach discomfort
Serious Side Effects (Consult your doctor right away)
- Severe, watery diarrhoea accompanied by fever and stomach cramps (a sign of a serious gut infection)
- Signs of an allergic reaction, including skin rash, hives, itching, or swelling of the face, tongue, and throat
- Involuntary muscle movements, facial twitching, or tremors
- An irregular, rapid, or pounding heartbeat
- Extreme dizziness or fainting
Medicines Containing this Salt
View AllDrug Warnings
- Always take on an empty stomach: Plan to take your dose at least 15 to 30 minutes before your morning meal to ensure maximum absorption and symptom control.
- Be mindful of bone health: Using acid-reducing medicines for more than a year may slightly increase the risk of bone fractures. Consult your doctor about taking calcium or vitamin D supplements.
- Watch for movement changes: This medication contains a component that can rarely cause involuntary muscle spasms or tremors, particularly in elderly patients. Notify your doctor immediately if you notice any unusual twitching.
- Do not stop therapy early: Even if you start feeling completely better, continue taking the medication for the full course prescribed by your doctor to prevent your symptoms from returning.
- Check for drug interactions: Always provide your pharmacist with a complete list of all prescriptions, over-the-counter drugs, and herbal supplements you are taking before starting Cinitapride+rabeprazole.
Drug Interactions
Inform your doctor if you are taking any of the following medicines, as they may interact.
- Antifungal medications (like ketoconazole or itraconazole): Name lowers stomach acid, which can significantly reduce how well these antifungal drugs are absorbed and work.
- Certain HIV medications (like atazanavir or nelfinavir): Reducing stomach acid may lower the absorption of these medicines, making them less effective at treating infection.
- Blood thinners (like warfarin): Combining these medications can increase the risk of bleeding, which may require your doctor to perform regular blood clotting tests.
- Digoxin: Low stomach acid levels can increase the absorption of digoxin, which raises the risk of experiencing drug toxicity.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption as it may lead to increased stomach acid production, thereby irritating the stomach lining and worsening the symptoms.
Pregnancy
unsafeCinitapride+rabeprazole is not recommended for pregnant women, especially in the first 3 months of pregnancy as it may cause harm to the foetus. Please consult a doctor if you are pregnant.
Breast Feeding
cautionIt is unknown whether Cinitapride+rabeprazole is excreted in human milk. Cinitapride+rabeprazole is given to breastfeeding mothers if the doctor thinks benefits are more significant than risks. Please consult a doctor if you are breastfeeding.
Driving
cautionCinitapride+rabeprazole may cause drowsiness in some people. Therefore, avoid driving or operating machinery if you feel drowsy after taking Cinitapride+rabeprazole.
Liver
cautionTake Cinitapride+rabeprazole with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Cinitapride+rabeprazole with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeCinitapride+rabeprazole is not recommended for children as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller, frequent meals: Consuming smaller portions throughout the day prevents your stomach from stretching excessively, which reduces the upward pressure on the lower oesophageal sphincter.
- Avoid trigger foods: Limit foods that stimulate acid production or relax the food pipe valve, such as chocolate, peppermint, citrus fruits, tomatoes, fatty foods, and spicy dishes.
- Keep upright after meals: Stay upright for at least two to three hours after eating. Avoid lying down, reclining, or bending over immediately after a meal.
- Raise the head of your bed: Elevate the head end of your bed by six inches using bed risers or a wedge pillow. This uses gravity to keep stomach acid from travelling up into your throat while you sleep.
- Avoid tight clothing: Do not wear tight belts, waistbands, or shaping garments that compress your abdomen, as this pressure can force acid upward.
Special Advise
Regular blood tests are recommended while taking Cinitapride+rabeprazole to monitor magnesium levels in the blood.
Cinitapride+rabeprazole may cause some abnormal liver enzyme and blood values. These changes are temporary and may return to normal after treatment with Cinitapride+rabeprazole is discontinued.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste in the mouth, and difficulty swallowing.
Peptic ulcers: These are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
Zollinger-Ellison syndrome: It is characterized by the formation of tumors in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.
FAQs
Cinitapride+rabeprazole is used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome.
Cinitapride+rabeprazole contains Rabeprazole and Cinitapride. Rabeprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid flowing back into the food pipe. On the other hand, Cinitapride increases the movement of the food pipe (oesophagus), small intestine and stomach, thereby enhancing bowel movement and digestive tract gets emptied from the food in a shorter time. Together, Cinitapride+rabeprazole helps in preventing acid reflux, thereby provides relief from hyperacidity and heartburn.
Cinitapride+rabeprazole may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery or bloody stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Cinitapride+rabeprazole to prevent dehydration.
Cinitapride+rabeprazole may cause low levels of magnesium in the blood if taken for more than 3 months. If you experience involuntary muscle contractions, fits, tiredness, increased heart rate or dizziness while taking Cinitapride+rabeprazole, please consult a doctor immediately as these might be signs of low magnesium levels. However, regular blood tests are recommended to monitor magnesium levels in the blood while taking Cinitapride+rabeprazole.
You are not recommended to take Cinitapride+rabeprazole with antifungals such as ketoconazole or itraconazole as it may reduce the effectiveness of antifungal against fungal infections. However, please consult your doctor before taking Cinitapride+rabeprazole with other medicines.
Cinitapride+rabeprazole should only be used for the duration prescribed by your doctor. Long-term use, especially for several months or years, may reduce the absorption of nutrients such as vitamin B12 and magnesium and may increase the risk of bone fractures in people with osteoporosis. Your doctor may recommend monitoring or supplements if prolonged treatment is necessary. Do not continue taking Cinitapride+rabeprazole longer than advised without medical supervision.
Cinitapride+rabeprazole should be used with caution in osteoporosis (weak and brittle bones) patients as it may worsen the condition especially if Cinitapride+rabeprazole is taken for more than 1 year as it increases the risk of fracture of the spine, hip or wrist. Therefore, inform your doctor if you have osteoporosis or take any steroids which may increase the risk of osteoporosis.
Cinitapride+rabeprazole may cause tardive dyskinesia (involuntary and abnormal movements) in elderly patients if taken for a prolonged time. Therefore, it is recommended to use Cinitapride+rabeprazole only for the duration as prescribed by a doctor.
Yes, Cinitapride+rabeprazole should always be taken on an empty stomach, usually 15 to 30 minutes before your morning meal. Taking it with food can reduce its effectiveness. Talk to your doctor or pharmacist if you need help planning your doses.
You should avoid drinking alcohol while taking Cinitapride+rabeprazole. Alcohol can irritate your stomach lining, trigger excess acid production, and worsen your reflux symptoms, reducing the effectiveness of the treatment. Talk to your doctor or pharmacist for more information.
The safety of Cinitapride+rabeprazole during pregnancy is not fully established. If you are pregnant, planning to become pregnant, or breastfeeding, do not take this medication unless your doctor has specifically prescribed it after evaluating the risks. Talk to your doctor to explore safer options.
Yes, dizziness is a known, though usually mild, side effect of this medicine. If you feel dizzy, avoid driving, riding a bicycle, or operating tools and machinery until you are certain you can perform these activities safely.
Take the missed dose as soon as you remember on an empty stomach. If it is almost time for your next scheduled dose, skip the missed one and continue with your normal routine. Do not take a double dose to make up for a missed one.
Yes. Although uncommon, Cinitapride+rabeprazole may cause involuntary muscle movements such as twitching, tremors, muscle stiffness, or abnormal facial and body movements, particularly in older adults or with prolonged use because of the Cinitapride component. Long-term use of the Rabeprazole component may also lower magnesium levels, which can cause muscle cramps, twitching, seizures, tiredness, dizziness, or an irregular heartbeat. If you develop any unusual muscle movements or symptoms suggestive of low magnesium, stop taking the medicine and contact your doctor immediately. Your doctor may recommend blood tests to monitor magnesium levels during long-term treatment.
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