CLINIDIPINE belongs to the class of blood pressure-lowering medications called 'calcium channel blockers' primarily used to treat hypertension. Hypertension is a medical condition in which blood pressure is elevated persistently in the blood vessels (arteries). If hypertension is left, untreated can lead to heart disease and stroke attack.
CLINIDIPINE contains 'Clinidipine' that helps dilates (widens) blood vessels, thereby increasing the heart's blood flow. The phenomena of vasodilation (widening) of the heart’s blood vessels reduce the heart's workload and muscles. Thus, CLINIDIPINE improves the blood flow and oxygen delivery to the heart tissue, thereby lowering the raised blood pressure on the blood vessel's arteries.
Take CLINIDIPINE as prescribed by the doctor. In some cases, CLINIDIPINE can cause side effects like sleepiness, oedema (fluid retention), ankle swelling, fatigue, headache, flushing (feeling warmth in the face, ears, neck and trunk), dizziness, palpitations (irregular heartbeat), stomach upset and abdominal pain. Most of these side effects of CLINIDIPINE do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
If you are known to be allergic to CLINIDIPINE or any other medicines, please inform your doctor. Before taking CLINIDIPINE, let your doctor know if you have any heart, kidney or liver problems, diabetes, hypotension (low blood pressure), electrolyte imbalance and dehydration. Avoid potassium supplements with CLINIDIPINE as it may lead to high potassium levels in the blood. Pregnant or breastfeeding women should also consult their doctor before taking CLINIDIPINE. Please do not stop taking CLINIDIPINE on your own, as it may lead to the recurrence of symptoms or worsen the disease. Do not consume alcohol with CLINIDIPINE as it may increase the risk of low blood pressure.
Hypertension (high blood pressure).
CLINIDIPINE is an anti-hypertensive drug that treats high blood pressure (hypertension). It contains Clinidipine, a calcium channel blocker that dilates (widens) blood vessels and increases blood flow. Clinidipine works by widening the heart’s blood vessels and reduces peripheral vascular resistance (constriction of blood vessels that leads to high blood pressure). Reduced peripheral vascular resistance improves the blood flow and oxygen delivery to the heart tissue.
Monitor your blood pressure levels regularly. Brief your medical history if you have kidney or liver problems, severe dehydration, low blood pressure, diabetes and heart diseases (aortic stenosis, heart failure) before starting CLINIDIPINE. Too much sweating, diarrhoea, or vomiting while using CLINIDIPINE may lead to dehydration, hence it is advised to drink enough fluids. Consult your doctor before using CLINIDIPINE if you are a pregnant or breastfeeding mother. Complete the course strictly as suggested by the doctor, even if you feel better, to avoid disease recurrence. Avoid consumption of alcohol with CLINIDIPINE as it may increase the risk of low blood pressure. Safety and effectiveness of CLINIDIPINE in paediatric patients has not been established.
Drug-Drug Interaction: CLINIDIPINE may interact with heart-related drugs (quinidine), anticancer drugs (aldesleukin), fits medicine (phenytoin), antibiotics (rifampicin, erythromycin) and other blood pressure medicines.
Drug-Food Interaction: Do not consume alcohol, grapefruit, or grapefruit juice, as it may increase the side effects of CLINIDIPINE.
Drug-Disease Interaction: People with low blood pressure, kidney or liver problems, severe dehydration, diabetes and heart diseases should consult the doctor before taking CLINIDIPINE.
It is unsafe to consume alcohol, since alcohol consumption with CLINIDIPINE may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.
It is not known if CLINIDIPINE affects pregnancy. Consult your doctor before taking CLINIDIPINE if you plan to become pregnant or already pregnant. Your doctor will weigh the potential risks and benefits before prescribing CLINIDIPINE.
There is no evidence on how CLINIDIPINE affects breastfeeding. Please consult your doctor before taking CLINIDIPINE if you are breastfeeding.
CLINIDIPINE may cause side effects like dizziness, headaches, nausea or tiredness, which can affect your ability to concentrate and drive. Hence, it is recommended not to drive or operate machinery until you are mentally alert.
Let your doctor know if you have any history of liver diseases before taking CLINIDIPINE. The dosage will be initiated in lower doses and will be further increased in patients with liver diseases. However, CLINIDIPINE is not recommended in patients with severe hepatic impairment.
Let your doctor know if you have any history of kidney diseases before taking CLINIDIPINE.
Safety and effectiveness of CLINIDIPINE in paediatric patients has not been established.
Hypertension: It is a medical condition in which blood pressure is elevated persistently in the arteries. It is considered as an essential risk factor for cardiovascular diseases and can be caused due to obesity, diabetes, smoking, high salt intake, stress, lack of physical activity or ageing. Blood pressure is measured in the ratio of systolic pressure to diastolic pressure. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Ideal blood pressure range lies in between 90/60 mmHg and 120/80 mmHg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.