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About DICLOFENAC+PARACETAMOL+TIZANIDINE

DICLOFENAC+PARACETAMOL+TIZANIDINE is a combination medicine that contains pain relievers and muscle relaxants. It is used to treat spasticity (muscle stiffness and spasms) associated with pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a muscle cramp or feel tight or stiff, like a knot.

DICLOFENAC+PARACETAMOL+TIZANIDINE contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol blocks prostaglandins (PGs) that cause pain and swelling. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. As a result, DICLOFENAC+PARACETAMOL+TIZANIDINE helps to reduce muscle stiffness, spasms, and pain. In addition, paracetamol lowers the high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.

DICLOFENAC+PARACETAMOL+TIZANIDINE is prescribed medication, and it should be taken as directed by the doctor. In some cases, you may experience common side effects such as vomiting, diarrhoea, headaches, drowsiness and ringing in your ears (tinnitus), fluctuations in blood pressure, dry mouth, stomach upsets, and a decrease or increase in heart rate. Most of these side effects do not require medical attention and will resolve gradually. If any of these effects persist, consult your doctor.

Avoid taking DICLOFENAC+PARACETAMOL+TIZANIDINE if you are allergic to any of its components. Before taking DICLOFENAC+PARACETAMOL+TIZANIDINE, tell your doctor about your medical history and other medications you are currently taking to rule out any possible side effects. DICLOFENAC+PARACETAMOL+TIZANIDINE is not recommended for use in pregnancy. If you are breastfeeding, consult your doctor before taking DICLOFENAC+PARACETAMOL+TIZANIDINE. This medicine may cause dizziness, so drive only if you are alert and focused. DICLOFENAC+PARACETAMOL+TIZANIDINE should not be given to children as safety has not been established. Avoid consuming alcohol while on treatment with DICLOFENAC+PARACETAMOL+TIZANIDINE as it could lead to liver damage.

Uses of DICLOFENAC+PARACETAMOL+TIZANIDINE

Spasticity (muscle stiffness and spasms) is associated with pain.

Medicinal Benefits

DICLOFENAC+PARACETAMOL+TIZANIDINE contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol inhibit the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, DICLOFENAC+PARACETAMOL+TIZANIDINE aids in relieving muscle stiffness, spasms, and pain. Besides this, paracetamol reduces elevated temperature by altering the chemical messengers in the brain area that regulates body temperature.

Directions for Use

Swallow the tablet as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DICLOFENAC+PARACETAMOL+TIZANIDINE

  • Vomiting
  • Diarrhoea
  • Headaches
  • Drowsiness
  • Ringing in your ears (tinnitus)
  • Fluctuations in blood pressure
  • Dry mouth
  • Stomach upsets
  • Decrease or increase in heart rate

In-Depth Precautions and Warning

Drug Warnings

Do not take DICLOFENAC+PARACETAMOL+TIZANIDINE if you are allergic to its components. Inform your doctor about all your medical conditions, especially if you have/ had hepatotoxicity, hypotension, renal dysfunction or renal toxicities, asthma, fluid retention, GI toxicity, rash, or thrombosis (blood clots). It is not recommended to take DICLOFENAC+PARACETAMOL+TIZANIDINE during pregnancy or whilst breastfeeding. DICLOFENAC+PARACETAMOL+TIZANIDINE may cause drowsiness and dizziness, so drive only when you are alert. DICLOFENAC+PARACETAMOL+TIZANIDINE is not recommended for children as safety and effectiveness have not been established. Do not stop taking DICLOFENAC+PARACETAMOL+TIZANIDINE unless your doctor tells you to. Treatment with DICLOFENAC+PARACETAMOL+TIZANIDINE should be stopped gradually. Stopping treatment suddenly may cause effects such as an increase in heart rate and high blood pressure.

Drug Interactions

Drug-Drug Interactions: DICLOFENAC+PARACETAMOL+TIZANIDINE may interact with certain pain killers (e.g. hydrocodone), anti-depressants (e.g. fluvoxamine, escitalopram), antibiotics (e.g. ciprofloxacin), antihypertensives (e.g. metoprolol), anticoagulant (e.g. apixaban), certain painkillers (e.g. celecoxib), and antiretroviral medicine (e.g. tenofovir).

Drug-Food Interactions: Do not drink alcohol while taking DICLOFENAC+PARACETAMOL+TIZANIDINE.

Drug-Disease Interactions: DICLOFENAC+PARACETAMOL+TIZANIDINE may interact with various disease conditions that include ulcer or perforation, bleeding problems, hepatotoxicity (liver impairment), hypotension, renal dysfunction or toxicities, asthma, fluid retention, GI toxicity, rash, thrombosis (blood clots).

Drug-Drug Interactions Checker List:

  • HYDROCODONE
  • FLUVOXAMINE
  • ESCITALOPRAM
  • CIPROFLOXACIN
  • METOPROLOL
  • APIXABAN
  • CELECOXIB
  • TENOFOVIR
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol while taking DICLOFENAC+PARACETAMOL+TIZANIDINE as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      DICLOFENAC+PARACETAMOL+TIZANIDINE is not recommended for use in pregnant women. If you are pregnant or planning pregnancy, consult your doctor before taking DICLOFENAC+PARACETAMOL+TIZANIDINE.

    • Safety Warning

      Breast Feeding

      caution

      DICLOFENAC+PARACETAMOL+TIZANIDINE is generally not recommended for use in breastfeeding mothers. If you are breastfeeding, consult your doctor before taking DICLOFENAC+PARACETAMOL+TIZANIDINE.

    • Safety Warning

      Driving

      caution

      DICLOFENAC+PARACETAMOL+TIZANIDINE may cause dizziness or drowsiness. So, do not drive or operate machinery unless you are alert after taking DICLOFENAC+PARACETAMOL+TIZANIDINE.

    • Safety Warning

      Liver

      caution

      Inform your doctor before taking DICLOFENAC+PARACETAMOL+TIZANIDINE if you have a liver impairment/disorder history. DICLOFENAC+PARACETAMOL+TIZANIDINE is not recommended for use in patients with severely impaired liver function.

    • Safety Warning

      Kidney

      caution

      Inform your doctor before receiving DICLOFENAC+PARACETAMOL+TIZANIDINE if you have a kidney impairment/disorder history. DICLOFENAC+PARACETAMOL+TIZANIDINE is not recommended for use in patients with severely impaired kidney function.

    • Safety Warning

      Children

      unsafe

      DICLOFENAC+PARACETAMOL+TIZANIDINE is not recommended for children as safety and effectiveness are not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Regular exercise helps muscle stretch, making them less likely to spasm, tear, and sprain. Mild activities such as jogging and walking are helpful for muscle stretching.
    • Massages can also be helpful.
    • Rest well, and get plenty of sleep.
    • Change your position at least every two hours to avoid developing pressure sores.
    • Hot or cold therapy can help treat muscle spasms.
    • Apply an ice pack or hot pack on the muscle for 15-20minutes.
    • Stay hydrated, drink plenty of water.

    Patients Concern

    Disease/Condition Glossary

    Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or feel tight or hard, like a knot.

     

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

    FAQs

    How does DICLOFENAC+PARACETAMOL+TIZANIDINE work?

    DICLOFENAC+PARACETAMOL+TIZANIDINE contains Diclofenac, Paracetamol and Tizanidine. Diclofenac and Paracetamol inhibit the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, DICLOFENAC+PARACETAMOL+TIZANIDINE aids in relieving muscle stiffness, spasms, and pain. In addition, paracetamol lowers the high temperature by affecting the chemical messengers in an area of the brain that regulates body temperature.

    Does DICLOFENAC+PARACETAMOL+TIZANIDINE cause diarrhoea?

    Diarrhoea might be a side-effect of DICLOFENAC+PARACETAMOL+TIZANIDINE. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Does DICLOFENAC+PARACETAMOL+TIZANIDINE cause dry mouth?

    Dry mouth could be a side-effect of DICLOFENAC+PARACETAMOL+TIZANIDINE. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.

    I have stomach ulcers. Can I use DICLOFENAC+PARACETAMOL+TIZANIDINE?

    Taking DICLOFENAC+PARACETAMOL+TIZANIDINE can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking DICLOFENAC+PARACETAMOL+TIZANIDINE if you have gastrointestinal bleeding or other bleeding problems before using DICLOFENAC+PARACETAMOL+TIZANIDINE.

    Can I take DICLOFENAC+PARACETAMOL+TIZANIDINE along with ciprofloxacin?

    It is not advisable to take DICLOFENAC+PARACETAMOL+TIZANIDINE and ciprofloxacin simultaneously. Inform your doctor if you are now using or have recently used ciprofloxacin. Your doctor may advise you to take these two medications at different times.

    Available Medicines for

    DICLOFENAC+PARACETAMOL+TIZANIDINE