DONEPEZIL+MEMANTINE is a combination drug containing a 'neurological medicine,' primarily used to treat Alzheimer's disease (memory loss). Alzheimer's disease is a progressive neuro disorder that affects the brain. It causes the brain to shrink (atrophy) and brain cells (neurons) to die.
DONEPEZIL+MEMANTINE is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor that works by preventing the breakdown of the chemical acetylcholine and improving the function of nerve cells in the brain. Memantine works by lowering the level of the chemical in the brain which is responsible to cause symptoms of Alzheimer's disease. Together, both of them balance the levels of chemical messengers in the brain and help transmit nerve signals.
Take DONEPEZIL+MEMANTINE as prescribed by your doctor. You are advised to take DONEPEZIL+MEMANTINE for as long as your doctor has prescribed it for you, depending upon your medical condition. Preferably take it before just bedtime. In some cases, you may experience vomiting, weight loss, loss of appetite, dryness in the mouth, dizziness, nausea, diarrhoea, and headache. Most of these side effects of DONEPEZIL+MEMANTINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
DONEPEZIL+MEMANTINE may cause dizziness and sleepiness. So, do not drive a car or operate any machinery that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking DONEPEZIL+MEMANTINE as it may cause diarrhoea. Before using DONEPEZIL+MEMANTINE, inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma.
Alzheimer’s disease (memory loss)
DONEPEZIL+MEMANTINE is a combination medication containing Donepezil and Memantine, which treat Alzheimer’s disease. It helps to slow down the progression of moderate to severe Alzheimer's by improving memory and thinking. It also increases the levels of a chemical messenger involved in the transmission of nerve signals. Donepezil is a cholinesterase inhibitor that works by improving the function of nerve cells in the brain by preventing the breakdown of the chemical acetylcholine. Memantine works by lowering the level of chemicals in the brain, which is responsible for causing symptoms of Alzheimer's disease. Together, they balance the levels of chemical messengers in the brain and help transmit nerve signals.
Do not take DONEPEZIL+MEMANTINE if you are allergic to DONEPEZIL+MEMANTINE or any of its ingredients. DONEPEZIL+MEMANTINE may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Increase the intake of fluids to keep yourself hydrated while taking DONEPEZIL+MEMANTINE as it may cause diarrhoea. Before using DONEPEZIL+MEMANTINE, inform your doctor if you have ever had heart problems, stomach ulcers, epilepsy, or asthma. Take DONEPEZIL+MEMANTINE preferably just before bedtime.
Drug-Drug Interaction: DONEPEZIL+MEMANTINE is known to interact with pain killers (aspirin), anticholinergics (donepezil), antiparkinson's disease (amantadine), ketamine, dextromethorphan), anti-fungal (ketoconazole), anti-epilepsy medicines (phenytoin, carbamazepine, phenobarbital), corticosteroid (dexamethasone), anti-tuberculosis medicines (rifampin), stomach ulcer medicines (cimetidine, ranitidine), dopaminergic agonists (bromocriptine).
Drug-Food Interaction: $name is known to interact with alcohol as it might increase sleepiness.
Drug-Disease Interaction: DONEPEZIL+MEMANTINE is known to interact in patients with kidney or liver disease, asthma, heart disease, history of seizures, stomach ulcers, history of intestinal bleeding, urination problems, bladder obstruction.
Taking alcohol, along with DONEPEZIL+MEMANTINE, may increase its drowsiness effect and cause excessive sleepiness.
DONEPEZIL+MEMANTINE is a pregnancy category C drug. It is not known whether it will harm the baby. So, take only if prescribed by a doctor.
It is not known whether DONEPEZIL+MEMANTINE passes through breast milk or not. So, caution should be exercised if you are breastfeeding.
DONEPEZIL+MEMANTINE is known to cause drowsiness, so please do not drive a car or operate any machinery which requires mental alertness.
DONEPEZIL+MEMANTINE to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.
DONEPEZIL+MEMANTINE to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.
The safety and efficacy of DONEPEZIL+MEMANTINE in children have not been established.
Alzheimer's disease: It is a progressive neurologic disorder that affects the brain. It causes the brain to shrink (atrophy) and brain cells to die. One of the very common causes of Alzheimer's disease is dementia (memory loss), which affects the person's ability to function independently. Very early signs of the disease are forgetting recent events and conversations, and as the disease progresses, it can lead to severe memory impairment.