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Empagliflozin+linagliptin

About Empagliflozin+linagliptin

Empagliflozin+linagliptin is a prescription medicine used to lower blood sugar levels in adults with type 2 diabetes. It combines empagliflozin and linagliptin in a single tablet and is used alongside a balanced diet and regular physical activity to improve blood sugar control. Managing diabetes can sometimes feel challenging, and this medicine is one part of a broader care plan designed to support your long-term health.

Take Empagliflozin+linagliptin regularly at the same time each day, exactly as prescribed by your doctor. It can be taken with or without food. Continue following your recommended diet, physical activity, blood sugar monitoring, and other parts of your diabetes care plan.

Some people may experience urinary tract infections, genital yeast infections, runny nose, sore throat, diarrhoea, or stomach upset. Consult your doctor right away if you develop severe stomach pain, persistent vomiting, difficulty breathing, severe dehydration, or signs of a serious allergic reaction.

Before starting Empagliflozin+linagliptin, tell your doctor if you have kidney problems, heart failure, a history of pancreatitis, frequent urinary or genital infections, or a previous episode of diabetic ketoacidosis. This medicine is not used to treat type 1 diabetes or diabetic ketoacidosis and is not recommended for people receiving dialysis.

Empagliflozin+linagliptin may interact with diuretics, insulin, and certain other diabetes medicines, which may increase the risk of dehydration, low blood pressure, or low blood sugar. Excessive alcohol intake may also increase the risk of ketoacidosis or low blood sugar. If you are pregnant, planning a pregnancy, breastfeeding, or an older adult, consult your doctor before starting treatment.

Uses of Empagliflozin+linagliptin

Empagliflozin+linagliptin is used to manage blood sugar levels in individuals with type 2 diabetes mellitus. The detailed uses of Empagliflozin+linagliptin include: • Treatment of type 2 diabetes mellitus: Empagliflozin+linagliptin helps lower elevated blood glucose levels by increasing insulin release, decreasing glucose production in the liver, and enhancing urinary glucose excretion. • Improved glycaemic control: The combination of empagliflozin and linagliptin offers complementary mechanisms to improve blood sugar regulation throughout the day, especially after meals.

Medicinal Benefits

When used alongside a balanced diet and regular physical activity, Empagliflozin+linagliptin helps improve blood sugar control and supports the long-term management of type 2 diabetes.

  • Improves blood sugar control: Helps lower high blood sugar levels and keep them within the target range.
  • Supports long-term health: Better blood sugar control may help reduce the risk of diabetes-related complications affecting the nerves, kidneys, eyes, and other parts of the body.
  • May support heart health: Empagliflozin may help reduce the risk of cardiovascular death and hospitalisation due to heart failure in certain adults with type 2 diabetes and established heart disease.
  • Simplifies treatment: Combines two diabetes medicines in a single tablet, which may make the treatment plan easier to follow.

Directions for Use

  • Empagliflozin+linagliptin can be taken with or without food.
  • It is recommended to take Empagliflozin+linagliptin once daily in the morning or as advised by your doctor.
  • Swallow Empagliflozin+linagliptin as a whole with a glass of water.
  • Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Empagliflozin+linagliptin

Common Side Effects (Usually mild):

  • Urinary tract infections (symptoms like a burning feeling when urinating)
  • Yeast infections (in men or women)
  • Runny nose or sore throat
  • Mild diarrhoea or upset stomach


Serious Side Effects (Consult your doctor right away):

  • Dehydration (feeling very thirsty, dizzy, or confused)
  • Ketoacidosis (high acid levels in the blood, causing nausea, vomiting, stomach pain, or trouble breathing)
  • Severe joint pain
  • Severe allergic reactions (swelling of the face, lips, or throat, or trouble swallowing)
  • Severe skin reactions or blistering

Drug Warnings

  • Watch for dehydration: Drink enough water throughout the day. Consult your doctor if you feel unusually thirsty, dizzy, light-headed, weak, or faint, especially during hot weather or if you have vomiting or diarrhoea.
  • Maintain good personal hygiene: Keep the genital area clean and dry to help reduce the risk of genital yeast infections. Consult your doctor if you develop itching, redness, burning, swelling, pain, or unusual discharge.
  • Know the warning signs of ketoacidosis: Nausea, vomiting, stomach pain, unusual tiredness, confusion, or deep or difficult breathing may be signs of ketoacidosis, even if your blood sugar is not very high. If these symptoms occur, go to the nearest emergency department immediately. Do not wait, and let the medical team advise you about your medicine.
  • Limit alcohol intake: Excessive alcohol intake may increase the risk of ketoacidosis or low blood sugar. Follow your doctor’s advice about alcohol use during treatment.
  • Inform your doctor before surgery: Tell your doctor if you have a planned surgery or medical procedure. You may need to stop Empagliflozin+linagliptin temporarily before the procedure and restart it only when your doctor advises.

Drug Interactions

Some medicines may affect how Empagliflozin+linagliptin works or increase the risk of side effects. Tell your doctor about all prescription medicines, over-the-counter medicines, and supplements you take.

  • Insulin and sulfonylureas: Taking these medicines with Empagliflozin+linagliptin may increase the risk of low blood sugar. Your doctor may adjust the dose of insulin or the sulfonylurea.
  • Diuretics: Water pills may increase fluid loss and raise the risk of dehydration or low blood pressure, especially in older adults or people with kidney problems.
  • Blood pressure medicines: Some medicines used to lower blood pressure may further reduce blood pressure when taken with Empagliflozin+linagliptin. Your doctor may monitor your blood pressure, fluid levels, and kidney function.

Drug-Drug Interactions Checker List:

  • METOPROLOL
  • PROPRANOLOL
  • TIMOLOL
  • GLIMEPIRIDE
  • INSULIN GLARGINE
  • LITHIUM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Limit alcohol while taking this medication because it can increase your risk of developing low blood sugar and a high ketone level.

    • Safety Warning

      Pregnancy

      consult your doctor

      During pregnancy, this medication should be used only when needed. Discuss the risks and benefits with your doctor. And also, discuss a plan with your doctor for managing your blood sugar while pregnant. Your doctor may change your diabetes treatment during pregnancy (such as diet and medications, including insulin).

    • Safety Warning

      Breast Feeding

      consult your doctor

      Consult your doctor; there is no substantial research yet on using Empagliflozin+linagliptin in breastfeeding/nursing mothers.

    • Safety Warning

      Driving

      unsafe

      You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Do not drive, use machinery, or do any activity requiring alertness or clear vision until you can safely perform such activities.

    • Safety Warning

      Liver

      caution

      Empagliflozin+linagliptin to be taken with caution, especially if you have a history of liver diseases/conditions. Please consult the doctor before taking medicine. Your doctor will weigh the benefits and potential risks before prescribing them.

    • Safety Warning

      Kidney

      caution

      Empagliflozin+linagliptin to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor depending on your renal functions. Empagliflozin+linagliptin is not recommended in severe kidney disease. Regular monitoring of kidney function tests is therefore important if you're taking Empagliflozin+linagliptin. Please consult the doctor before taking medicine. Your doctor will weigh the benefits and potential risks before prescribing them.

    • Safety Warning

      Children

      consult your doctor

      It is not known if Empagliflozin+linagliptin is safe and effective in children under 18 years of age. Please consult the doctor if you have any doubts or concerns regarding this. Your doctor will weigh the benefits and any potential risks before prescribing them.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Stay well-hydrated: Because this medication helps remove sugar through your urine, you will lose more fluids than usual. Drink plenty of water throughout the day to prevent dehydration.
    • Monitor carbohydrate intake: Work with a dietitian to plan meals that focus on complex carbohydrates (like whole grains and vegetables) to prevent sudden blood sugar spikes.
    • Exercise regularly: Aim for at least 150 minutes of moderate physical activity, like brisk walking, per week to help your body use insulin more efficiently.
    • Check your feet daily: Diabetes can affect your circulation and nerves. Inspect your feet daily for any cuts, sores, or redness to prevent infections.
    • Track your blood sugar: Regularly test your blood sugar levels as directed by your doctor to monitor how well the medicine and lifestyle changes are working.

    Special Advise

    • Keep taking Empagliflozin+linagliptin even if your blood sugar levels are controlled. If you miss a dose, do not take a larger dose. Consult your treating physician for advice.
    • Take short, frequent meals, and avoid prolonged fasting when taking Empagliflozin+linagliptin. Beware of symptoms of hypoglycaemia (low blood sugar) which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Make sure to carry these with you at all times, especially during long travels.
    • It is always better that your physician knows about any underlying conditions like kidney or liver disease, prior heart attack, alcohol intake, etc., before the doctor prescribes Empagliflozin+linagliptin.
    • Remember, lifestyle modifications are the most important step in controlling blood sugar levels.

    Patients Concern

    Disease/Condition Glossary

    Type 2 diabetes: Type 2 diabetes is a chronic or lifelong disease that prevents the body from properly utilizing insulin. Hence, people with type 2 diabetes either do not produce enough insulin or resist insulin action. Middle-aged or older are most likely to suffer from type 2 diabetes, also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. There may be weight gain in some cases, while weight loss may be observed in rare cases. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increased chance of heart attack or stroke.

    FAQs

    Empagliflozin+linagliptin is a combination drug that belongs to the anti-diabetic class. It is used to treat Type 2 diabetes.

    If you have symptoms like increased hunger, thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact the doctor, as it can be a condition of type 2 diabetes.

    If you feel your blood sugar level is decreasing and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar levels in your body. So, it is advisable to keep sugar candies with you.

    No. Empagliflozin+linagliptin is only prescribed to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.

    Empagliflozin+linagliptin contains Empagliflozin and Linagliptin. It is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Empagliflozin works by increasing the removal of sugar by your kidneys. At the same time, Linagliptin works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also decrease the amount of sugar your liver makes.

    Empagliflozin+linagliptin should be avoided in patients allergic to any of the components or excipients of this medicine. It should be avoided in patients with moderate to severe kidney or liver disease. Using this drug is also not advised if you drink too much alcohol. Make sure to inform your healthcare professional if you are pregnant or breastfeeding.

    No. To date, no clinical evidence states that Empagliflozin+linagliptin affects fertility in either men or women. If you have any doubts/concerns regarding this, please discuss the risks and benefits with your doctor.

    Type 2 diabetes is a chronic or lifelong disease that prevents the body from properly utilizing insulin. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision.

    Empagliflozin+linagliptin can be taken with metformin if prescribed by the doctor. Please consult the doctor if you have any concerns.

    Empagliflozin+linagliptin should be swallowed as a whole with water; do not crush or chew it.

    Empagliflozin+linagliptin should be used only by the people for whom the doctor has prescribed the medicine.

    Empagliflozin+linagliptin may cause side effects such as frequent urination, dizziness, or light-headedness. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

    If you miss a dose of Empagliflozin+linagliptin take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and the next dose at the scheduled time.

    Store Empagliflozin+linagliptin at room temperature (20°C to 25°C). Keep it out of sight and reach of children.

    Look out for signs and consult the doctor if you have kidney disease, dehydration, pancreatitis (inflammation of the pancreas), gallstones, low blood pressure, heart failure, high cholesterol, yeast infections in the vagina or penis, blocked or narrowed blood vessels, usually in the leg, nerve problems (such as diabetic peripheral neuropathy), foot sores or ulcers, or amputation.

    Empagliflozin+linagliptin is generally not recommended during pregnancy because it may affect the developing baby. If you are pregnant, planning a pregnancy, or think you may be pregnant, consult your doctor. Your doctor will recommend a suitable treatment to help manage your blood sugar safely during pregnancy.

    While Empagliflozin+linagliptin alone rarely causes low blood sugar, it can happen when combined with other diabetes drugs. If you feel shaky, sweaty, or dizzy, consume a fast-acting sugar source like fruit juice or hard candy, and talk to your doctor.

    Yes, some people experience moderate weight loss while taking Empagliflozin+linagliptin because it helps your body eliminate excess sugar and calories through your urine. Talk to your doctor to understand what to expect.

    Yes, Empagliflozin+linagliptin is designed to work alongside a healthy diet and regular exercise. Medication alone cannot manage type 2 diabetes effectively. Talk to your doctor or a dietitian for personalised nutritional advice.

    In some cases, especially if you are dehydrated, Empagliflozin+linagliptin can affect kidney function. Your doctor will likely perform blood tests to check your kidneys before and during your treatment. Talk to your doctor if you experience decreased urination or swelling in your legs.

    No, you should not stop taking Empagliflozin+linagliptin without consulting your healthcare provider. Stopping the medication abruptly can cause your blood sugar levels to spike again. Talk to your doctor before making any changes.

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