Enalaprilat
About Enalaprilat
Enalaprilat is a prescription medication given by injection to treat severe high blood pressure, especially when oral medications are not suitable or cannot be taken. It belongs to a group of medicines that help relax blood vessels, making it easier for the heart to pump blood throughout the body.
Because this medication is injected directly into a vein, it is typically given at regular intervals under the close supervision of a healthcare provider in a hospital or clinic. While food does not affect how this medicine is absorbed, making healthy diet and lifestyle changes, such as reducing salt intake and managing stress, is essential to achieve the best long-term results for your blood pressure.
While taking this medicine, some people may experience mild side effects like dizziness, lightheadedness, or a dry cough. However, you must contact your doctor immediately if you experience serious side effects, such as swelling of your face, lips, tongue, or throat, which can make breathing difficult.
Do not take this if you have a history of severe allergic reactions (angioedema) to similar blood pressure medications, or if you are pregnant. Before receiving this medicine, talk to your doctor if you have kidney disease, diabetes, or a history of heart problems.
This medication can interact with other blood pressure drugs, lithium, and potassium supplements. Drinking alcohol while receiving this treatment can cause a sudden, severe drop in blood pressure. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe for you.
Uses of Enalaprilat
Medicinal Benefits
Enalaprilat helps rapidly lower dangerously high blood pressure in emergency and hospital settings. When administered under medical supervision, it provides fast blood pressure control, protects vital organs, and supports safe recovery during acute medical conditions.
- Provides Rapid Blood Pressure Control: Because this medicine is given directly into the bloodstream, it begins working within minutes to quickly lower dangerously high blood pressure when immediate treatment is needed.
- Protects the Heart and Vital Organs: By reducing blood pressure promptly, this medicine helps decrease the workload on the heart and lowers the risk of serious complications such as stroke, heart attack, and damage to other vital organs.
- Useful When Oral Medicines Cannot Be Taken: This injectable treatment is an effective option for patients who are unable to swallow tablets due to surgery, severe illness, or unconsciousness, ensuring reliable blood pressure control in a monitored medical setting.
Directions for Use
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Enalaprilat is administered by the doctor or healthcare professional.
- Do not self-administer.
Storage
Side Effects of Enalaprilat
Common Side Effects (Usually mild):
- Dizziness or lightheadedness
- A persistent dry cough
- Feeling faint when standing up quickly
- Nausea
Serious Side Effects (Consult a doctor right away):
- Swelling of the face, lips, tongue, or throat (difficulty breathing or swallowing)
- Severe stomach pain
- Yellowing of the eyes or skin (signs of liver damage)
- Unexplained muscle weakness or irregular heartbeats
- Severe dizziness or fainting
Medicines Containing this Salt
View AllDrug Warnings
- Always inspect the liquid inside the vial before use. It should be clear and colourless. Do not use the medicine if it looks cloudy, discoloured, or contains visible particles.
- If injecting at home, safely discard used needles and syringes in an approved sharps disposal container. Never reuse needles.
- To prevent dizziness or falls, rise very slowly when standing up from a sitting or lying position.
- Monitor your blood pressure daily and keep a log to share with your healthcare team at your next appointment.
- Do not take this medicine if you are pregnant, as it can cause severe harm or death to an unborn baby. Use reliable birth control and tell your doctor immediately if you think you might be pregnant.
Drug Interactions
- Other blood pressure medications: Combining these can cause your blood pressure to drop too low.
- Potassium supplements or potassium-sparing water pills: May cause dangerously high levels of potassium in your blood.
- Lithium: This medicine can raise lithium levels in your body, increasing the risk of lithium toxicity.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): May reduce the effectiveness of Enalaprilat and increase the risk of severe kidney damage.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeDo not consume alcohol while on treatment with Enalaprilat as it may worsen the side effects like dizziness and also may increase blood pressure.
Pregnancy
unsafeThe use of Enalaprilat is contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Inform your doctor if you are pregnant before receiving Enalaprilat.
Breast Feeding
unsafeEnalaprilat may be excreted in human milk. Therefore, it is not recommended for breastfeeding mothers as it may be unsafe for the baby. Inform your doctor if you are breastfeeding before receiving Enalaprilat. Your doctor will decide whether you stop breastfeeding or discontinue the use of Enalaprilat based on the benefits and risks.
Driving
cautionEnalaprilat may cause dizziness. Hence, do not drive or operate machines after receiving this medicine.
Liver
cautionIf you have a pre-existing or a history of liver disease, inform your doctor before receiving Enalaprilat. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Elderly patients with liver impairment should start the treatment with a lower dose.
Kidney
cautionIf you have a pre-existing or a history of kidney disease, inform your doctor before receiving Enalaprilat. Enalaprilat may cause renal failure in some patients. Hence, inform your doctor if the patient develops any symptoms. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Elderly patients with renal impairment should start the treatment with a lower dose.
Children
unsafeEnalaprilat is not recommended for use in children as the safety and efficacy are not established for this age group.
Habit Forming
Diet & Lifestyle Advise
- Eat a low-sodium diet to help keep your blood pressure within a healthy, stable range.
- Avoid using salt substitutes that contain potassium, as this medicine can naturally raise potassium levels in your blood to unsafe levels.
- Stay adequately hydrated, but consult your doctor about your daily fluid limits if you have a history of heart or kidney issues.
- Avoid drinking alcohol, as it can combine with the medication to cause an unsafe drop in blood pressure.
Special Advise
- Sudden withdrawal may worsen angina (chest pain). However, if you experience chest pain, consult your doctor immediately.
- Frequent monitoring of blood pressure is important while receiving this medicine.
- Abnormal liver and kidney tests must be reported to the doctor.
- Your doctor may suggest a blood test for serum electrolytes (sodium, potassium), and a CBC to check for the occurrence of hyponatremia and hypokalaemia.
Patients Concern
Disease/Condition Glossary
Hypertension: Also called high blood pressure, is a serious condition in which the force exerted by the blood against the artery walls becomes high. This hardens the heart to pump blood. Raised blood pressure can cause chest pain (angina), heart attack (when the blood supply to the heart is blocked), stroke (brain damage) and kidney failure. Enalaprilat is used in treating hypertension and thus helps reduce further risk. The blood pressure can be diagnosed with the help of a blood pressure monitor called a sphygmomanometer.
FAQs
Enalaprilat is used to treat hypertension.
Enalaprilat contains Enalaprilat, which works by reducing the production of certain substances that cause an increase in blood pressure. This allows the blood to flow more smoothly and makes the heart more efficient at pumping blood throughout the body.
It is advised to continue your medicine even after your blood pressure is controlled or becomes normal, as it can shoot up at any time. If you have a persistent headache, please consult your doctor immediately.
The chances of missing a dose of Enalaprilat are very low. If you forget to take a dose or miss the appointment, consult your doctor and receive your next dose on time.
It is given as an injection or infusion directly into a vein, typically by a healthcare provider in a clinic or hospital setting. Talk to your doctor.
No, this medicine should not be used during pregnancy as it can cause serious injury or death to an unborn baby. Talk to your doctor.
This medicine blocks certain enzymes, which can lead to a buildup of natural substances in your respiratory tract that trigger a dry, tickling cough. Talk to your doctor.
It is highly recommended to avoid alcohol, as it can interact with the medicine to cause severe dizziness, lightheadedness, or fainting. Talk to your doctor.
Sit or lie down immediately to avoid falling. Avoid sudden movements, and let your healthcare provider know right away. Talk to your doctor.
You should avoid salt substitutes containing potassium, as they can cause your blood potassium levels to rise dangerously high when combined with this medicine. Talk to your doctor.

