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About ESMOLOL

ESMOLOL belongs to the group of medicines called beta-blockers used for the short-term treatment of fast heartbeat. It is also used during and straight after surgery to treat high blood pressure and/or fast heartbeat.
 
ESMOLOL contains Esmolol, which works by controlling the force and rate of heartbeat. It also helps reduce the blood pressure. Thereby, it helps slow down the heart rate and reduce blood pressure.
 
In some cases, ESMOLOL may cause side effects such as a fall in blood pressure, excessive sweating, loss of appetite, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Do not use ESMOLOL if you are pregnant or breastfeeding. ESMOLOL is not recommended for children below 18 years as the efficacy and safety have not been established. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of ESMOLOL

Fast heartbeat and high blood pressure

Medicinal Benefits

ESMOLOL belongs to the group of medicines called beta-blockers used for the short-term treatment of tachycardia (heartbeats too fast). It is also used during and straight after surgery to treat high blood pressure and/or fast heartbeat. ESMOLOL contains Esmolol, which works by controlling the force and rate of heartbeat. It also helps reduce the blood pressure. Thereby, it helps slow down the heart rate and reduce blood pressure.

Directions for Use

ESMOLOL will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of ESMOLOL

  • A fall in blood pressure
  • Excessive sweating
  • Loss of appetite
  • Dizziness
  • Headache
  • Weakness
  • Fatigue (tiredness)
  • Nausea and vomiting

In-Depth Precautions and Warning

Drug Warnings

ESMOLOL should not be used if you are allergic to any of its components if you have a very slow heartbeat, severe heart block, low blood pressure, problems with blood supply to the heart, serious heart failure symptoms, phaeochromocytoma (hormone-secreting tumour occurring in the adrenal glands), asthma symptoms that are worsening rapidly, or metabolic acidosis (increased levels of acid in the body). Inform the doctor if you are being treated for certain heart rhythm disorders/heart problems or if you are taking other heart medicines if you have high blood pressure, diabetes, asthma, heart failure, heart block, skin problems, chest pain/angina, circulatory problems, kidney problems, psoriasis, or hyperthyroidism (overactive thyroid). ESMOLOL is not recommended during pregnancy, breastfeeding, and for children below 18 years.

Drug Interactions

Drug-Drug Interaction: Inform the doctor if you are taking medicines used to lower blood pressure or heart rate, calcium channel blockers (nifedipine), anti-diabetics, pain killers (floctafenine), antipsychotics (amisulpride, clozapine), tricyclic antidepressants (imipramine, amitriptyline), anticonvulsant (phenobarbital), anti-hypertensives (reserpine, clonidine, moxonidine), or blood thinner (warfarin).

Drug-Food Interaction: No interactions found/established.

Drug-Disease Interaction: Inform the doctor if you have bradyarrhythmia (slow heart rate), cardiogenic shock, low blood pressure, congestive heart failure, diabetes, ischemic heart disease, cerebrovascular insufficiency, glaucoma, overactive thyroid, myasthenia gravis, psoriasis, asthma/COPD, or kidney problems.

Drug-Drug Interactions Checker List:

  • NIFEDIPINE
  • AMISULPRIDE
  • CLOZAPINE
  • IMIPRAMINE
  • AMITRIPTYLINE
  • PHENOBARBITAL
  • RESERPINE
  • CLONIDINE
  • MOXONIDINE
  • WARFARIN
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      Taking alcohol with esmolol may have additive effects in lowering blood pressure. Therefore, avoid or limit the consumption of alcohol.

    • Safety Warning

      Pregnancy

      unsafe

      The use of ESMOLOL is not recommended during pregnancy.

    • Safety Warning

      Breast Feeding

      unsafe

      Esmolol may pass into breast milk. ESMOLOL is not recommended if you are breastfeeding.

    • Safety Warning

      Driving

      consult your doctor

      It is not known if ESMOLOL affects your ability to drive. Drive or operate heavy machinery only if you are alert.

    • Safety Warning

      Liver

      consult your doctor

      If you have liver disease, inform the doctor before receiving ESMOLOL.

    • Safety Warning

      Kidney

      caution

      Caution is advised in patients with kidney problems. If you have kidney problems, inform the doctor before receiving ESMOLOL.

    • Safety Warning

      Children

      unsafe

      ESMOLOL is not recommended for children below 18 years as safety and effectiveness have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • You are advised to consume a low-salt and low-fat diet.
    • Regular exercise is also recommended.
    • Eat a diet rich in whole grains, vegetables and fruits.
    • Avoid smoking and alcohol consumption.
    • Maintain a healthy weight with proper diet and exercise.
    • Manage stress with meditation, yoga, and massage.

    Patients Concern

    Disease/Condition Glossary

    High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels, leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, the signs and symptoms of hypertension are none.

    Tachycardia: It is a condition in which the heart beats faster than usual, usually 100 beats per minute. Symptoms include lightheadedness/dizziness, palpitations/rapid heartbeat, fatigue, shortness of breath, chest discomfort, and fainting.

    FAQs

    How does ESMOLOL work?

    ESMOLOL works by controlling the force and rate of heartbeat. It also helps reduce the blood pressure.

    Is ESMOLOL safe for patients with diabetes?

    Consult the doctor if you have diabetes, as ESMOLOL may mask the symptoms of low blood sugar or increase the effects of diabetic medicines. Regular monitoring of blood glucose levels is advised.

    I have kidney problems. Is it safe to use ESMOLOL?

    You could develop hyperkalemia (high blood potassium levels), which might lead to serious heart problems if you have kidney disease or need kidney dialysis. Therefore, consult the doctor if you have kidney problems.

    Can I receive ESMOLOL with verapamil?

    You should not receive ESMOLOL within 48 hours of stopping verapamil. Consult the doctor if you have any concerns.

    Available Medicines for

    ESMOLOL