GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).
GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE contains Gabapentin, methylcobalamin, and nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Methylcobalamin helps protect and rejuvenate the nerve cells and nerve fibres. Together, GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE helps in providing relief from neuropathic pain.
You are advised to take GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE may cause dizziness, sleepiness, tiredness, headache, nausea, vomiting, dry mouth, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Consult your doctor if you are pregnant or breastfeeding. GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE may cause sleepiness and dizziness, so drive only if you are alert. Limited data is available regarding the usage of GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE in children, so please consult a doctor if you have any concerns. Avoid consuming alcohol with GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.
Neuropathic pain
GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE contains Gabapentin (anti-convulsant), Methylcobalamin (vitamin), and Nortriptyline (tricyclic antidepressant). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline works by increasing the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Methylcobalamin helps protect and rejuvenate the nerve cells and nerve fibres. Together, GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE helps in providing relief from neuropathic pain.
Do not take GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE if you are allergic to any of its contents. Inform your doctor if you have/had heart problems, bipolar syndrome, thyroid disorder, epilepsy, high blood pressure, diabetes, urinary retention, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE may cause sleepiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Drug-Drug Interactions: GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE may interact with hypnotics (zolpidem), antidepressants (duloxetine, escitalopram, sertraline), pain killers (hydrocodone, acetaminophen), anti-histamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), anti-convulsant (pregabalin, topiramate), anti-anxiety (alprazolam), anti-emetic (ondansetron).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have heart problems, pheochromocytoma (tumour of the adrenal gland), depression, seizures, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, glaucoma, diabetes, thyroid problems, suicidal tendency, hemodialysis, kidney or liver problems.
Avoid consumption of alcohol while taking GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE as it may cause increased dizziness and sleepiness.
Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
Consult your doctor if you are breastfeeding; your doctor will decide whether GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE can be taken by breastfeeding mothers or not.
GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE may cause dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Limited information is available regarding the usage of GABAPENTIN+METHYLCOBALAMIN+NORTRIPTYLINE in children. Please consult your doctor.
Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It occurs by chronic progressive nerve disease, infection, or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).