Opinentin Trio Tablet 10's
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About Opinentin Trio Tablet 10's
Opinentin Trio Tablet 10's is used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).
Opinentin Trio Tablet 10's contains Gabapentin, methylcobalamin, and nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Methylcobalamin helps protect and rejuvenate the nerve cells and nerve fibres. Together, Opinentin Trio Tablet 10's helps in providing relief from neuropathic pain.
You are advised to take Opinentin Trio Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Opinentin Trio Tablet 10's may cause dizziness, sleepiness, tiredness, headache, nausea, vomiting, dry mouth, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Consult your doctor if you are pregnant or breastfeeding. Opinentin Trio Tablet 10's may cause sleepiness and dizziness, so drive only if you are alert. Limited data is available regarding the usage of Opinentin Trio Tablet 10's in children, so please consult a doctor if you have any concerns. Avoid consuming alcohol with Opinentin Trio Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.
Uses of Opinentin Trio Tablet 10's
Opinentin Trio Tablet 10's is used in the treatment of type 2 diabetes mellitus. The detailed uses of Opinentin Trio Tablet 10's are as follows:
- Type 2 diabetes mellitus: Opinentin Trio Tablet 10's reduces high blood sugar levels in individuals suffering with type 2 diabetes.
- Improvement of postprandial blood glucose control: Opinentin Trio Tablet 10's delays glucose absorption in the intestine, effectively reducing post-meal sugar spikes.
- Enhancement of insulin secretion: Opinentin Trio Tablet 10's stimulates the pancreas to release insulin when needed, thus helping in better glucose utilization.
- Reduction of hepatic glucose production: Opinentin Trio Tablet 10's decreases sugar production in the liver, which helps to improve glycemic control.
- Support in insulin resistance: Opinentin Trio Tablet 10's enhances the body's sensitivity to insulin, particularly in overweight individuals.
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Directions for Use
- Opinentin Trio Tablet 10's can be taken with or without food as prescribed by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, chew, or break it.
Key Benefits
Opinentin Trio Tablet 10's contains Gabapentin (anti-convulsant), Methylcobalamin (vitamin), and Nortriptyline (tricyclic antidepressant). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline works by increasing the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Methylcobalamin helps protect and rejuvenate the nerve cells and nerve fibres. Together, Opinentin Trio Tablet 10's helps in providing relief from neuropathic pain.
How Opinentin Trio Tablet 10's Works
Storage
What if I have taken an overdose of Opinentin Trio Tablet 10's
Drug Warnings
Do not take Opinentin Trio Tablet 10's if you are allergic to any of its contents. Inform your doctor if you have/had heart problems, bipolar syndrome, thyroid disorder, epilepsy, high blood pressure, diabetes, urinary retention, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Opinentin Trio Tablet 10's may cause sleepiness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Opinentin Trio Tablet 10's as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Drug-Drug Interactions
Drug-Drug Interactions
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Coadministration of Opinentin Trio Tablet with Ziprasidone can increase the risk or severity of irregular heart rhythm.
How to manage the interaction:
Taking Opinentin Trio Tablet with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
Coadministration of Opinentin Trio Tablet with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.
How to manage the interaction:
Taking Opinentin Trio Tablet with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Co-administration of Opinentin Trio Tablet with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).
How to manage the interaction:
Taking Opinentin Trio Tablet with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Using Opinentin Trio Tablet together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).
How to manage the interaction:
Taking Isocarboxazid with Opinentin Trio Tablet is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
Coadministration of Opinentin Trio Tablet with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.
How to manage the interaction:
Taking Opinentin Trio Tablet with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Coadministration of Opinentin Trio Tablet with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).
How to manage the interaction:
Taking Opinentin Trio Tablet with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
Coadministration of Opinentin Trio Tablet with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).
How to manage the interaction:
Taking Opinentin Trio Tablet with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
Taking fentanyl with other drugs that cause central nervous system depression, such as Opinentin Trio Tablet, might result in an increased risk of adverse effects.
How to manage the interaction:
Although combining Fentanyl and Opinentin Trio Tablet may cause an interaction, they can be used if advised by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
Co-administration of Butorphanol and Opinentin Trio Tablet may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).
How to manage the interaction:
Although there is a possible interaction between Opinentin Trio Tablet and Butorphanol, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
Using Ketamine together with Opinentin Trio Tablet may increase side effects.
How to manage the interaction:
Although taking Ketamine and Opinentin Trio Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
Include food rich in vitamin B and D in your diet.
Exercising regularly helps in improving overall health and combating pain.
Rest well. Get optimum sleep.
Include cayenne pepper in your diet, as it can help in lowering neuropathic pain.
Try taking a warm bath, as it can be soothing.
Avoid smoking and alcohol consumption.
Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
Acupuncture can be helpful by stimulating pressure points.
Using essential oils for massages can help increase circulation.
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Alcohol
Safe if prescribed
Avoid consumption of alcohol while taking Opinentin Trio Tablet 10's as it may cause increased dizziness and sleepiness.
Pregnancy
Consult your doctor
Please consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
Consult your doctor
Consult your doctor if you are breastfeeding; your doctor will decide whether Opinentin Trio Tablet 10's can be taken by breastfeeding mothers or not.
Driving
Safe if prescribed
Opinentin Trio Tablet 10's may cause dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
Liver
Consult your doctor
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
Consult your doctor
Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
Safe if prescribed
Limited information is available regarding the usage of Opinentin Trio Tablet 10's in children. Please consult your doctor.
Heart
Opinentin Trio Tablet 10's should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Opinentin Trio Tablet 10's.
Geriatrics
Consult your doctor
Opinentin Trio Tablet 10's should be given to elderly patients only if prescribed by a doctor. If you have any concerns about the dosage, please consult your doctor.
FAQs
Opinentin Trio Tablet 10's is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain.
Opinentin Trio Tablet 10's works by binding to the specific site on voltage-gated calcium channels and decreases the movement of pain receptors. It also helps protect and rejuvenate the nerve cells and nerve fibres.
Opinentin Trio Tablet 10's may cause constipation. Eat fibre-rich food and drink plenty of fluids if you experience constipation. If the condition persists or worsens, consult a doctor.
To treat your condition effectually, continue taking Opinentin Trio Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Opinentin Trio Tablet 10's.
Dry mouth could be a side-effect of Opinentin Trio Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Opinentin Trio Tablet 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet. Consult your doctor if you have any concerns.
Opinentin Trio Tablet 10's combines three medicines: Gabapentin, Methylcobalamin, and Nortriptyline. Together, they are used to treat neuropathic pain (nerve pain).
Peripheral neuropathy is a condition that happens when the nerves outside your brain and spinal cord (called peripheral nerves) are damaged. It mainly affects the nerves in your hands, feet, and arms. This can lead to numbness, tingling, weakness, and pain, usually in the hands or feet. Diabetes, infections, injuries, or certain medications can cause it.
Yes, Opinentin Trio Tablet 10's may cause sleepiness or drowsiness in some people as a side effect. However, it's essential to note that everyone's response to Opinentin Trio Tablet 10's can vary. If you're experiencing excessive sleepiness or concerns about Opinentin Trio Tablet 10's, consult your doctor or pharmacist for personalized guidance.
No, it is crucial to follow the prescribed dosage for Opinentin Trio Tablet 10's. Taking more than the recommended dose can increase the risk of side effects, such as dizziness, drowsiness, dry mouth, or even more serious complications. If you feel that the current dose is not practical or if your symptoms worsen, please consult your doctor. They can evaluate your situation and adjust the dose if needed.
Opinentin Trio Tablet 10's should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach of children.
The common side effects of Opinentin Trio Tablet 10's include dizziness, sleepiness, tiredness, headache, nausea, vomiting, dry mouth, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
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Reference
- https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020235s064_020882s047_021129s046lbl.pdf
- https://medlineplus.gov/druginfo/meds/a682620.html
- https://www.drugs.com/gabapentin.html
- https://www.drugs.com/nortriptyline.html
- https://wellonapharma.com/product/finished/gabapentin-and-methylcobalamin-tablets
