Gliclazide+metformin+voglibose
About Gliclazide+metformin+voglibose
Gliclazide+metformin+voglibose is indicated in treating type 2 diabetes mellitus. Type 2 diabetes is a chronic condition where the body either doesn't produce enough insulin or doesn't use insulin effectively.
Gliclazide+metformin+voglibose contains Voglibose, Metformin, and Gliclazide. Voglibose prevents the breakdown of complex sugars into simple sugars such as glucose. Gliclazide acts by increasing the insulin released by the pancreas. Metformin acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's response to insulin.
Gliclazide+metformin+voglibose should be taken with food to avoid an upset stomach. Gliclazide+metformin+voglibose should be taken at the same time every day for the best results. For better advice, your doctor will decide what dose should be taken, which can change quickly depending on your condition.
The common side effects of Gliclazide+metformin+voglibose are low blood sugar, dizziness, and dry mouth. If any of the side effects persist or worsen, please consult your doctor.
If you are allergic to any of the ingredients in Gliclazide+metformin+voglibose, please tell your doctor. You should not take Gliclazide+metformin+voglibose if you have diabetic ketoacidosis (excess acids in your blood). Please inform your doctor if you have any heart disease, are planning to get pregnant, or are breastfeeding.
Uses of Gliclazide+metformin+voglibose
Medicinal Benefits
- Gliclazide+metformin+voglibose is a combination medicine used to manage Type 2 Diabetes Mellitus.
- It helps to control high blood sugar levels, thereby preventing complications associated with diabetes.
- Voglibose (an alpha-glucosidase inhibitor) slows down the breakdown and absorption of complex carbohydrates into simple sugars.
- It helps prevent a sudden spike in blood sugar levels after meals (postprandial hyperglycemia).
- Gliclazide (a sulfonylurea) stimulates the pancreas to release more insulin, aiding in the reduction of blood glucose levels.
- Metformin (a biguanide) reduces glucose production in the liver, delays glucose absorption from the intestines and enhances insulin sensitivity, helping the body use insulin more effectively.
- This medicine helps maintain optimal blood sugar control throughout the day.
- Proper management of blood sugar levels helps in preventing long-term complications of diabetes such as nerve damage, kidney disease, and vision problems.
- Gliclazide+metformin+voglibose works best when combined with healthy lifestyle changes such as a balanced diet, regular exercise, and weight management.
Directions for Use
- Take Gliclazide+metformin+voglibose with food to reduce stomach upset.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Swallow the medicine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Gliclazide+metformin+voglibose
- Hypoglycemia (low blood glucose level)
- Dizziness
- Sweating
- Palpitations
- Hunger pangs
- Dry mouth and skin
Drug Warnings
- Do not take Gliclazide+metformin+voglibose if you are allergic to any of its components.
- Gliclazide+metformin+voglibose should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease.
- Inform your doctor if you are taking any other medicines or have pre-existing medical conditions.
- Consult your doctor if you are pregnant or breastfeeding.
- Some diabetic patients taking Gliclazide+metformin+voglibose may develop a rare but serious condition called lactic acidosis. In this condition, excessive lactic acid accumulates in the blood.
- Gliclazide+metformin+voglibose should not be stopped even if you feel better, without consulting your doctor. If you stop taking Gliclazide+metformin+voglibose abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).
Drug Interactions
Drug-Drug Interactions: Gliclazide+metformin+voglibose may interact with insulin, blood pressure-lowering pills (hydrochlorothiazide, amlodipine, metoprolol), water pills/diuretics (furosemide), heart failure-related medicines (digoxin), steroids (prednisolone), and thyroid hormones. So, tell your doctor if you are using these drugs before taking Gliclazide+metformin+voglibose.
Drug-Food Interactions: Taking Gliclazide+metformin+voglibose with alcoholic beverages may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis (build-up of lactic acid in the blood) and hypoglycemia.
Drug-Disease Interactions: Inform your doctor if you have a vitamin B12 deficiency, kidney problems, liver problems, cardiovascular disease (heart-related issues), or low blood sugar level (hypoglycemia).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Gliclazide+metformin+voglibose to avoid unpleasant side effects.
Pregnancy
cautionIt is recommended to consult your doctor before taking this drug if you are pregnant.
Breast Feeding
cautionGliclazide+metformin+voglibose should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Gliclazide+metformin+voglibose.
Driving
cautionGliclazide+metformin+voglibose may cause hypoglycemia (low blood sugar levels), whose symptoms include unusual sleepiness, shivering, palpitations, sweating, etc. This may affect your ability to drive. Use caution while driving or doing anything that requires concentration.
Liver
cautionGliclazide+metformin+voglibose to be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.
Kidney
cautionGliclazide+metformin+voglibose to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.
Children
unsafeThe safety and efficacy of Gliclazide+metformin+voglibose in children have not been established. Gliclazide+metformin+voglibose is not recommended in children.
Habit Forming
Diet & Lifestyle Advise
- Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grains.
- Eat at regular intervals. Do not take a long gap between a meal or snack.
- Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
- Invest in at least 150 minutes of moderate-intensity physical activity and 15 minutes of high-intensity exercise weekly.
- Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
- Replace refined carbohydrate-containing foods with whole grain foods and increase intake of fruits, veggies, and other fibre-enriched foods.
- Reduce saturated fat (or hidden fats) intake in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
- Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga or meditation to control stress related to blood sugar changes.
- Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).
- Keep your blood pressure as normal (120/80) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
Special Advise
- Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose. Consult your treating physician for advice.
- Take short, frequent meals, and avoid prolonged fasting when taking this drug. Beware of hypoglycemia symptoms, including sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the symptoms mentioned above, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels.
- Try to quit smoking and reduce your intake of carbohydrate-rich foods like potatoes, rice, mangoes, bread, sugar, etc.
- Remember, lifestyle modifications are the most important step in controlling blood sugar levels.
- To avoid hypoglycemia, you should not miss meals and also carry some form of sugar with you.
Patients Concern
Disease/Condition Glossary
Diabetes Mellitus type 2: Type 2 diabetes is a chronic condition where the body either doesn't produce enough insulin or doesn't use insulin effectively. Symptoms of type 2 diabetes include feeling exhausted all the time, feeling thirsty, having blurry vision, and having the urge to urinate (pee) more often. Complications of type 2 diabetes include skin infection, eye problems (retinopathy), nerve damage (neuropathy), delayed wound healing, diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure, and even stroke.
FAQs
Gliclazide+metformin+voglibose is used to treat type 2 diabetes mellitus. It prevents blood glucose levels from rising to very high levels, thus keeping your diabetes under control.
Eating nutritious food with a good workout regimen with Gliclazide+metformin+voglibose can make a lot of difference in managing type 2 diabetes. Exercising causes the heartbeat to be a little faster and breathing to be harder, making muscles use more glucose and lower sugar levels. It also helps in making insulin so that the body works better.
Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.
Hypoglycemia refers to low blood sugar levels, and it is one of the side effects of Gliclazide+metformin+voglibose. Gliclazide+metformin+voglibose helps to lower blood glucose levels and to make them as normal as possible. Still, sometimes it may also cause Hypoglycemia, which may also occur if you miss or delay your food, drink alcohol, over-exercise, or take other antidiabetic medicine along with this medicine. It is important to monitor blood sugar levels regularly.
It is suggested to take other medicines only after consulting with a doctor to avoid unpleasant side effects. Tell your doctor if you have taken other medicines or herbal supplements while taking Gliclazide+metformin+voglibose.
If you feel thirsty after taking Gliclazide+metformin+voglibose, it may be because of dehydration or loss of fluids. Increase intake of fluids. If even then you feel thirsty, please consult your doctor.
It has been reported that long-term usage of Gliclazide+metformin+voglibose can cause vitamin B12 deficiency as it interferes with the absorption of vitamin B12 in the stomach. The symptoms of a vitamin B12 deficiency include fatigue, nerve problems, tingling sensation and numbness in hands and feet, weakness, urinary problems, affected mental status, and difficulty maintaining balance. These symptoms can be managed by taking Vitamin B12 supplements as advised by your doctor.
If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing, and frequent infections, contact the doctor, as it can be a condition of type 2 diabetes.
If you feel that your blood sugar level is decreasing and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.
Research has shown that regular exercise can significantly reduce the risk of developing type 2 diabetes. Even walking for an hour or being involved in any type of workout can help in losing weight and reduce the chances of developing diabetes.
Gliclazide+metformin+voglibose is a combination of three anti-diabetic drugs: Voglibose (alpha-glucosidase inhibitor), Metformin (biguanide), and Gliclazide (sulfonylurea).
