Glycopyrrolate+indacaterol
About Glycopyrrolate+indacaterol
Glycopyrrolate+indacaterol is used for long-term, maintenance treatment of chronic obstructive pulmonary disease (COPD).
Glycopyrrolate+indacaterol is a combination of two medicines: Indacaterol and Glycopyrrolate. Indacaterol relaxes and widens the airways, making it easier for air to enter and exit the lungs. Glycopyrrolate decreases the secretions in the airways. Together, Glycopyrrolate+indacaterol provides relief from COPD.
Use Glycopyrrolate+indacaterol strictly as prescribed by your doctor or as instructed on the label. In some cases, Glycopyrrolate+indacaterol may cause common side effects, such as upper respiratory tract infections, sinus inflammation, runny/stuffy nose, headache, dizziness, and stomach upset. Please talk to your doctor if you experience these side effects persistently.
Do not stop using Glycopyrrolate+indacaterol on your own, as this may worsen symptoms. Consult your doctor if you are pregnant or breastfeeding. Glycopyrrolate+indacaterol is not recommended for children under 18 years old, as safety and effectiveness have not been established.
Uses of Glycopyrrolate+indacaterol
• Management of chronic obstructive pulmonary disease: Glycopyrrolate+indacaterol helps improve airflow and makes it easier to breathe in COPD patients.
• Relief of bronchospasm: This combination relaxes the airway muscles, preventing bronchial constriction and reducing shortness of breath.
• Control of symptoms in chronic bronchitis and emphysema: Glycopyrrolate+indacaterol effectively manages persistent cough, wheezing, and mucus buildup.
• Maintenance treatment of airflow obstruction: It is used as a long-term maintenance therapy to improve lung function and quality of life.
• Prevention of COPD exacerbations: Regular use reduces the frequency and severity of flare-ups in stable COPD patients.
Medicinal Benefits
- Glycopyrrolate+indacaterol is used for long-term maintenance treatment of chronic obstructive pulmonary disease (COPD).
- It helps improve airflow and makes breathing easier in patients with COPD.
- It effectively manages persistent cough, wheezing, and mucus buildup.
- It prevents bronchial constriction and reduces shortness of breath.
- Regular use of Glycopyrrolate+indacaterol helps reduce the frequency and severity of flare-ups in stable COPD patients.
Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
- Place the mouthpiece between your lips, press the inhaler, and breathe in slowly. Hold your breath for a few seconds, then slowly breathe out.
- Rinse your mouth with water and spit it out to avoid fungal infections in the mouth and throat.
Storage
Side Effects of Glycopyrrolate+indacaterol
- Upper respiratory tract infection
- Nasopharyngitis (sore throat and runny nose)
- Runny or stuffy nose
- Headache
- Dizziness
- Stomach upset
Drug Warnings
Before taking Glycopyrrolate+indacaterol, inform your doctor if you:
- are allergic to any of its contents.
- are taking any medications for lung diseases.
- are pregnant or breastfeeding.
- have a history of asthma, seizures, diabetes, or glaucoma.
- have thyroid, heart, kidney, or liver problems.
- have difficulty in passing urine, high blood pressure, or gastrointestinal obstruction.
Drug Interactions
Drug-Drug Interactions: Glycopyrrolate+indacaterol may interact with certain medicines, either increasing side effects or altering its effects. Inform your doctor if you are taking any of the following:
- Beta-blockers (propranolol, carvedilol)
• Potential Effect: May reduce the treatment outcomes or medicinal benefits. - Alpha and beta-blockers (labetalol)
• Potential Effect: May reduce the medicinal benefits of both medications. Antidiabetic agents (pramlintide) - Antidiabetic agent (pramlintide)
• Potential Effect: May slow down stomach emptying or intestinal absorption of nutrients. - Cardiac glycosides (digoxin)
• Potential Effect: May increase serum concentration of digoxin and the risk of side effects. - Electrolyte supplements (potassium chloride)
• Potential Effect: May increase irritant effects on the stomach and intestine. - Antiparkinsonian drugs (levodopa)
• Potential Effect: May decrease the levodopa levels in the bloodstream.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Glycopyrrolate+indacaterol should be used with caution or avoided in people with:
- Heart problems
- Difficulty in urination
- Gastrointestinal obstruction
- Infectious diarrhoea
- Narrow-angle glaucoma (Increase in eye pressure)
- Epilepsy (seizures)
- Hypertension (high blood pressure)
- Myasthenia gravis (muscle weakness)
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are advised not to consume alcohol while taking Glycopyrrolate+indacaterol as it might cause increased dizziness.
Pregnancy
cautionGlycopyrrolate+indacaterol belongs to pregnancy category C. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor if you are breastfeeding; your doctor will decide whether Glycopyrrolate+indacaterol can be taken by breastfeeding mothers or not.
Driving
cautionGlycopyrrolate+indacaterol may cause dizziness. Drive or operate machinery only if you are alert.
Liver
cautionDose adjustment may be needed. Please consult your doctor if you have liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
unsafeGlycopyrrolate+indacaterol is not recommended for children below 18 years, as safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
Diet and Nutrition:
- Eat more high-protein foods, such as pulses, eggs, milk, curd, and lean meat, to help keep your breathing muscles strong.
- Choose fresh fruits and vegetables for antioxidant and immunity support.
- Have small, frequent meals to avoid breathlessness while eating.
- Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, and bottled lemon and lime juice, as they may worsen symptoms.
Preventive lifestyle measures:
- Quit smoking completely; it is the most important step to slow disease progression.
- Avoid dust, smoke, air pollution, and strong fumes as much as possible.
- Ensure adequate rest and sleep.
Physical activity and breathing care:
- Try meditation, deep breathing, regular exercise, and progressive muscle relaxation techniques to relieve stress and reduce your risk of an attack.
- Engage in regular, mild physical activity such as walking, as tolerated.
Monitoring parameters:
- Monitor for any changes in breathlessness, cough, sputum colour or quantity, and how often you have flare-ups.
- Keep track of oxygen saturation if advised by your doctor, along with regular and correct use of inhalers and response to treatment.
Patients Concern
Disease/Condition Glossary
Chronic Obstructive Pulmonary Disease (COPD): It is a group of lung diseases that includes emphysema (shortness of breath) and chronic bronchitis (inflammation of the bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to it. Common symptoms include chronic cough, shortness of breath, and wheezing (a whistling sound while breathing).
FAQs
Glycopyrrolate+indacaterol is used for long-term, maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD).
Glycopyrrolate+indacaterol contains Indacaterol and Glycopyrrolate. Indacaterol relaxes and widens the openings in the airways, making it easier for the air to get in and out of the lungs. Glycopyrrolate decreases the secretions in the airways. Together, Glycopyrrolate+indacaterol provides relief for those with COPD.
Glycopyrrolate+indacaterol is used for the maintenance treatment for COPD. It does not treat a sudden attack of wheezing or breathlessness. Use a rescue inhaler to treat sudden breathing problems.
Dry mouth may be a side effect of Glycopyrrolate+indacaterol. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum or candy may help stimulate saliva and thereby prevent mouth dryness.
Do not stop taking Glycopyrrolate+indacaterol on your own, as it might cause worsening of symptoms. To treat your condition effectually, continue taking Glycopyrrolate+indacaterol for as long as your doctor has prescribed it. Talk to your doctor if your breathing problems, wheezing, or cough do not improve or worsen.
No, Glycopyrrolate+indacaterol is not indicated for the treatment of asthma, as the safety and effectiveness of Glycopyrrolate+indacaterol in patients with asthma have not been established. Consult your doctor if you have asthma.
The safety of Glycopyrrolate+indacaterol during pregnancy or breastfeeding is not well established. It should only be used if prescribed by a doctor. Your doctor will evaluate whether the benefits outweigh the risks in your specific case.
Glycopyrrolate+indacaterol is not recommended for children under 18 years, as its safety and effectiveness have not been established for this age group.
If you are allergic to milk proteins, you should be cautious when taking Glycopyrrolate+indacaterol, as it may contain milk proteins or lactose (milk sugar). Always make sure that your doctor is aware of your allergies so they can determine whether this medication is safe for you.
Some people may experience common side effects such as a sore throat, sinus inflammation, a runny or blocked nose, headache, dizziness, or an upset stomach. These are usually mild and go away on their own without requiring medical attention. If these side effects persist or become bothersome, contact your doctor for further advice and management.
Store Glycopyrrolate+indacaterol at room temperature, away from heat, moisture, and direct sunlight. Keep it in a safe place, out of the reach of children. Do not freeze the medication.
