About IDARUCIZUMAB
IDARUCIZUMAB belongs to the group of medicines called anticoagulant reversal agents used during a medical emergency to treat severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots).
IDARUCIZUMAB contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran in order to inactivate its effect.
IDARUCIZUMAB will be administered by a healthcare professional; do not self-administer. In some cases, IDARUCIZUMAB may cause headaches, constipation, fever, low potassium levels, and confusion. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
Consult the doctor if you are pregnant or breastfeeding. The safety and effectiveness of IDARUCIZUMAB in children have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.
Uses of IDARUCIZUMAB
To treat severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots).
Medicinal Benefits
IDARUCIZUMAB belongs to the group of medicines called anticoagulant reversal agents indicated in patients treated with dabigatran (a medicine used to prevent blood clots) when reversal of the anticoagulant effects of dabigatran is needed for emergency surgery/urgent procedures, in life-threatening conditions or uncontrolled bleeding. IDARUCIZUMAB contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran in order to inactivate its effect.
Directions for Use
Storage
Side Effects of IDARUCIZUMAB
- Headache
- Constipation
- Fever
- Hypokalaemia (low potassium levels)
- Confusion
In-Depth Precautions and Warning
Drug Warnings
Inform the doctor if you are allergic to any of the components in IDARUCIZUMAB, if you have hereditary fructose intolerance or if you are on a sodium-restricted diet. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you are taking any other medicines, including supplements and herbal products.
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking monoclonal antibodies (rozanolixizumab, efgartigimod alfa).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Inform the doctor if you have fructose intolerance or liver impairment.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known if alcohol affects IDARUCIZUMAB. Please consult your doctor.
Pregnancy
cautionIDARUCIZUMAB should be given to pregnant women only if clearly needed. Inform the doctor if you are pregnant or think you may be pregnant.
Breast Feeding
cautionCaution is advised while administering IDARUCIZUMAB to a nursing woman.
Driving
not applicableThis medicine is for hospital use only.
Liver
consult your doctorIf you have a history of liver disease, inform your doctor before receiving IDARUCIZUMAB.
Kidney
consult your doctorIf you have a history of kidney disease, inform your doctor before receiving IDARUCIZUMAB.
Children
cautionThe safety and effectiveness of IDARUCIZUMAB in children have not been established.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Avoid smoking and alcohol consumption.
- Avoid fast food, fried food, processed meats, refined carbs and added sugar.
- Get optimal sleep; rest well.
Patients Concern
Disease/Condition Glossary
Bleeding: Bleeding is the loss of blood inside or outside the body. It is the main risk associated with dabigatran treatment. Severe or uncontrolled bleeding requires immediate medical attention to prevent loss of blood. Anticoagulant reversal agents such as IDARUCIZUMAB are used to treat severe and uncontrolled bleeding.
