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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Praxbind 2.5gm/50ml Solution For Injection is used in the treatment of severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots). It contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran to inactivate its effect. Common side effects of Praxbind 2.5gm/50ml Solution For Injection are headaches, constipation, fever, low potassium levels, and confusion.

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Whats That

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Composition :

IDARUCIZUMAB-50MG

Manufacturer/Marketer :

Boehringer Ingelheim India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Praxbind 2.5gm/50ml Solution For Injection

Praxbind 2.5gm/50ml Solution For Injection belongs to the group of medicines called anticoagulant reversal agents used during a medical emergency to treat severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots).

Praxbind 2.5gm/50ml Solution For Injection contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran in order to inactivate its effect.

Praxbind 2.5gm/50ml Solution For Injection will be administered by a healthcare professional; do not self-administer. In some cases, Praxbind 2.5gm/50ml Solution For Injection may cause headaches, constipation, fever, low potassium levels, and confusion. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.

Consult the doctor if you are pregnant or breastfeeding. The safety and effectiveness of Praxbind 2.5gm/50ml Solution For Injection in children have not been established. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Praxbind 2.5gm/50ml Solution For Injection

Treatment of severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots)

Directions for Use

Praxbind 2.5gm/50ml Solution For Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Praxbind 2.5gm/50ml Solution For Injection belongs to the group of medicines called anticoagulant reversal agents indicated in patients treated with dabigatran (a medicine used to prevent blood clots) when reversal of the anticoagulant effects of dabigatran is needed for emergency surgery/urgent procedures, in life-threatening conditions or uncontrolled bleeding. Praxbind 2.5gm/50ml Solution For Injection contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran in order to inactivate its effect.

How Praxbind 2.5gm/50ml Solution For Injection Works

Praxbind 2.5gm/50ml Solution For Injection contains Idarucizumab, a humanised monoclonal antibody fragment (Fab) which rapidly traps dabigatran in order to inactivate its effect.

Storage

Store in a cool and dry place away from sunlight
Side effects of Praxbind 2.5gm/50ml Solution For Injection
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Praxbind 2.5gm/50ml Solution For Injection

As Praxbind 2.5gm/50ml Solution For Injection is a parenteral formulation, the chance of overdose may be less. If you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

Inform the doctor if you are allergic to any of the components in Praxbind 2.5gm/50ml Solution For Injection, if you have hereditary fructose intolerance or if you are on a sodium-restricted diet. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Consult your doctor

It is not known if alcohol affects Praxbind 2.5gm/50ml Solution For Injection. Please consult your doctor.

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Pregnancy

Caution

Praxbind 2.5gm/50ml Solution For Injection should be given to pregnant women only if clearly needed. Inform the doctor if you are pregnant or think you may be pregnant.

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Breast Feeding

Caution

Caution is advised while administering Praxbind 2.5gm/50ml Solution For Injection to a nursing woman.

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Driving

Not applicable

This medicine is for hospital use only.

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Liver

Consult your doctor

If you have a history of liver disease, inform your doctor before receiving Praxbind 2.5gm/50ml Solution For Injection.

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Kidney

Consult your doctor

If you have a history of kidney disease, inform your doctor before receiving Praxbind 2.5gm/50ml Solution For Injection.

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Children

Caution

The safety and effectiveness of Praxbind 2.5gm/50ml Solution For Injection in children have not been established.

Have a query?

FAQs

Praxbind 2.5gm/50ml Solution For Injection is used to treat severe or uncontrolled bleeding that has been caused by taking dabigatran (a medicine used to prevent blood clots).

Praxbind 2.5gm/50ml Solution For Injection rapidly traps dabigatran in order to inactivate its effect.

Praxbind 2.5gm/50ml Solution For Injection may contain sorbitol, which can cause serious or life-threatening metabolic problems in people with hereditary fructose intolerance (a genetic disorder). Therefore, inform the doctor if you have hereditary fructose intolerance.

Praxbind 2.5gm/50ml Solution For Injection does not remove other medicines used to prevent the formation of blood clots. It will only remove dabigatran from your body.

Country of origin

India

Manufacturer/Marketer address

1102, Hallmark Business Plaza, 11Th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051
Other Info - PRA0330

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Keep Refrigerated. Do not freeze.

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