Lidocaine+nifedipine
About Lidocaine+nifedipine
Lidocaine+nifedipine is used in the treatment of anal fissures (tears in the lining of the anus). An anal fissure is usually a small tear or cut in the lining of the anus.
Lidocaine+nifedipine contains Lidocaine and Nifedipine, which help reduce pain, relax the muscles around the anus, and improve blood flow to promote faster healing of the fissure.
Use Lidocaine+nifedipine as advised by your doctor. Possible side effects of Lidocaine+nifedipine may include burning, itching, and redness. If any of these side effects persist or worsen, consult your doctor.
Do not use Lidocaine+nifedipine if you are allergic to any of its components. Inform your doctor before using Lidocaine+nifedipine if you plan to get pregnant, are pregnant, or breastfeeding.
Uses of Lidocaine+nifedipine
Medicinal Benefits
- Helps relieve pain, burning, and discomfort associated with anal fissures.
- Reduces anal muscle spasm and pressure, improving comfort during bowel movements.
- Promotes better blood flow to the affected area, supporting faster healing.
- Aids in soothing irritation and improves overall anal comfort.
Directions for Use
- Usually, Lidocaine+nifedipine is to be used twice daily; however, follow your doctor's advice regarding the dosage and duration.
- Apply Lidocaine+nifedipine to the affected rectal area using the applicator as suggested by the doctor.
- Discard the applicator after every single use and never reuse it. Never apply this medication with your finger; only use the applicator.
- Wash your hands immediately after using Lidocaine+nifedipine.
Storage
Side Effects of Lidocaine+nifedipine
- Application site reactions (burning, itching, redness)
Drug Warnings
- Avoid using Lidocaine+nifedipine if you are allergic to any of its components.
- Discuss your medical history, particularly if you have broken skin/infection in the area where the medicine is to be applied.
- Inform your doctor if you have heart disease, liver disease, or a kidney disorder.
- Do not use this medication more frequently or in larger doses than suggested, as it is absorbed through the skin and might have serious negative effects.
Drug Interactions
Drug-Drug Interactions: No interactions found.
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: No interactions found.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionYou are recommended to avoid alcohol consumption while taking Lidocaine+nifedipine. Alcohol intake, along with Lidocaine+nifedipine, may cause increased drowsiness.
Pregnancy
cautionInform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Lidocaine+nifedipine.
Breast Feeding
cautionInform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Lidocaine+nifedipine.
Driving
cautionLidocaine+nifedipine may cause drowsiness and sleepiness, so do not drive or operate heavy machinery if you feel drowsy.
Liver
cautionInform your doctor before using Lidocaine+nifedipine if you have a history of liver impairment/disorder. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionInform your doctor if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.
Children
cautionLimited information is available regarding the usage of Lidocaine+nifedipine in children, so please consult a doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
Stress Management and Relaxation:
- Practice mindfulness activities such as yoga to help reduce stress and manage pain.
- Spend time meditating, reading books, listening to relaxing music, or enjoying a warm bath.
- Engage in calming activities with family to promote mental relaxation.
Diet:
- Consume a high-fibre diet including fruits, vegetables, whole grains, and legumes to prevent constipation.
- Drink plenty of water throughout the day to keep stools soft.
- Include foods that support digestion, such as curd and probiotic-rich items.
- Avoid spicy, fried, and processed foods that may irritate the anal region.
Lifestyle Advice:
- Maintain regular bowel habits and avoid straining during bowel movements.
- Engage in light physical activity, such as walking, to improve digestion.
- Practice good anal hygiene by gently cleaning the area after bowel movements.
- Avoid prolonged sitting and take short breaks to reduce pressure on the anal area.
Patients Concern
Disease/Condition Glossary
Anal fissures: It is a small tear/cut in the lining of the anus. This cut in the skin may cause bleeding and severe pain during or after a bowel movement. This disease can affect people of all ages and is often seen in young children and infants, as constipation is common in these groups. The possible causes of an anal fissure include chronic constipation, trouble passing large or hard stool, frequent diarrhoea, tearing the skin around the anus, straining during childbirth, inflammatory bowel disease (IBD), etc. Some common symptoms of an anal fissure include a crack in the skin around the anus, pain during the passage of bowel movement, a small lump on the skin near the anal fissure, bright red stool, etc.
FAQs
Lidocaine+nifedipine is used in the treatment of anal fissures (tears in the lining of the anus).
Lidocaine+nifedipine is a combination of two different drugs: Lidocaine and Nifedipine. Lidocaine is a local anaesthetic. It blocks pain signals from the nerves to the brain, decreasing the pain sensation. Nifedipine is a calcium channel blocker (CCB). It works in anal fissures by blocking the action of calcium on the blood vessels of the anus. Altogether the Lidocaine+nifedipine works by relaxing the smooth muscles around the anus area and promoting the proper blood flow in that region that helps to heal the fissure quickly. Lidocaine+nifedipine also reduces the anal canal pressure, which diminishes the pain and spasm in the anal region.
A person with severe heart block or heart rhythm disorder is not allowed to use this medicine as it may lead to serious side effects.
Lidocaine+nifedipine belongs to a category of local anaesthesia that acts by blocking the nerve signals of a particular body area. In this way, this medicine numbs the specific area of the body and reduces the pain associated with anal fissures. Thus, the person does not feel pain anymore.
A person of age 65 or older should use Lidocaine+nifedipine with caution, as directed by the doctor, as the chances of occurrence of side effects increase in older people.
No, Lidocaine+nifedipine does not cure fissures, but it decreases inflammation of the mucous membrane and the skin. It reduces discomfort, reduces pain and itching, providing symptomatic relief.
Apply the missed portion as soon as you recall it. However, if it is time for another application, avoid the missed dose and proceed with your regular dosing plan. Try not to apply this medication frequently or more than the prescribed dose to relieve anal fissure problems, as this medicine gets absorbed through the skin and may lead to serious side effects.
Be careful and check that no injury occurs in the numb area as you will not feel the pain, but it will still hurt you the most after the action of Lidocaine+nifedipine ends.
Anal fissure generally occurs due to trauma or injury in the anal canal. The possible reasons for anal fissures include constipation, ongoing diarrhoea, and childbirth.
As Lidocaine+nifedipine is used externally on the skin it is less likely to interact with other medicines. However, you should always consult your doctor if you are taking other medicines such as cough cold medicines, medicine for high blood pressure, medicines for migraine, and medicine to dissolve a blood clot.
Before using Lidocaine+nifedipine, clean the affected area with gentle soap and water. Then rinse and pat dry the area. Gently fill the medication in the applicator and insert it just 1/2 to 1 inch inside the anus area. Also, apply the drug to the anal opening as advised by the doctor. To apply the medicine to the outside region of the anus, one should apply a small amount of Lidocaine+nifedipine to the affected area by gently rubbing it. Wash the hands immediately after using. Avoid the contact of the Lidocaine+nifedipine with the nose, ears, eyes, or mouth.
In most cases, fissures usually heal within a few weeks. But if they are not, it is due to the poor oxygen supply to these fissures which further slows down the healing process. Thus, these fissures fail to heal and continue to worsen. If you have been facing issues for more than a few weeks, you should consult a doctor immediately.
If you have fissures, you must eat a fiber-rich diet such as fresh fruits, vegetables, and whole grains. Drink plenty of water and avoid alcohol consumption to ensure that your stools are soft and easy to pass. If you are facing issues with digestion, you may also take fiber supplements or laxatives. Your doctor will recommend ways to avoid constipation and thereby promote healing of fissures.
No, spicy foods do not cause fissures. However, they can irritate the fissures and worsen your symptoms. Therefore, it is advised to avoid eating spicy foods if you are facing problems with your fissures.
Usually, fissures heal within a few weeks. But, if they persist for longer than 4 to 6 weeks, they are referred to as chronic fissures. Please consult your doctor immediately if you have been noticing fissures for more than 4 weeks.
You are recommended to take your doctor’s advice before using Lidocaine+nifedipine if you are pregnant or breastfeeding.
If you have severe kidney or liver disease, consult your doctor before using Lidocaine+nifedipine. Also, let your doctor know if you take any other medicines or supplements.
Lidocaine+nifedipine may cause side effects such as application site reactions, itching, swelling, tingling sensation, or rash. If these side effects persist or worsen, please consult your doctor.
Store Lidocaine+nifedipine at room temperature. Protect from light. Do not freeze. Keep it out of reach of children.
