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Metformin+teneligliptin

About Metformin+teneligliptin

Metformin+teneligliptin is a prescription medicine used to manage type 2 diabetes in adults. It contains metformin and teneligliptin, which work together to lower and control blood sugar levels when diet, exercise, or treatment with a single medicine is not enough. Keeping blood sugar within the target range may help reduce the risk of long-term diabetes-related complications.

Take Metformin+teneligliptin regularly and exactly as prescribed by your doctor. It is usually taken with or after a meal to help reduce digestive side effects such as nausea or an upset stomach. Continue following the recommended diet and exercise plan, as these are important parts of diabetes management.

Some people may experience nausea, diarrhoea, stomach discomfort, or headache. Low blood sugar may occur when Metformin+teneligliptin is taken with insulin or certain other diabetes medicines. Seek urgent medical help if you develop severe stomach pain that spreads to the back or symptoms of lactic acidosis, such as unusual tiredness, muscle pain, difficulty breathing, severe weakness, or feeling unusually cold.

Tell your doctor before starting Metformin+teneligliptin if you have kidney or liver problems, heart failure, severe dehydration, or a serious infection. Do not take this medicine if you have severe kidney impairment, diabetic ketoacidosis, or an allergy to metformin, teneligliptin, or any other ingredient in the medicine.

Tell your doctor about all medicines you take, especially insulin, other diabetes medicines, steroids, diuretics, or blood pressure medicines. Avoid excessive alcohol intake because it may increase the risk of lactic acidosis and affect blood sugar control. If you are pregnant, planning a pregnancy, breastfeeding, or an older adult, consult your doctor before taking this medicine.

Uses of Metformin+teneligliptin

Metformin+teneligliptin is used to treat type 2 diabetes. The detailed uses of Metformin+teneligliptin are as follows:
• Management of Type 2 Diabetes Mellitus: Metformin+teneligliptin improves glycemic control in adults with Type 2 Diabetes Mellitus.
• Improves Insulin Sensitivity: Metformin+teneligliptin helps the body respond better to insulin.
• Reduces Glucose Production: Metformin+teneligliptin suppresses excess sugar made by the liver.
• Adjunct to lifestyle and therapy: Metformin+teneligliptin is prescribed alongside a healthy diet, regular physical activity to manage type 2 diabetes more effectively.

Medicinal Benefits

Taking Metformin+teneligliptin brings several long-term and daily benefits to help you manage your health safely:

  • Stable Daily Blood Sugar: It helps prevent rapid blood sugar spikes after meals, allowing you to maintain steadier energy levels throughout the day.
  • Protection Against Serious Complications: By keeping your blood sugar within target ranges, it lowers your risk of developing diabetes-related complications, such as kidney damage, nerve pain, and vision loss.
  • Two Treatments in One Tablet: Combining two active therapies into a single daily tablet simplifies your routine, making it easier to stick to your treatment plan.

Directions for Use

  • Metformin+teneligliptin can be taken with or without food. However, taking it with food may help reduce stomach upset.
  • It is recommended to take Metformin+teneligliptin once daily or as advised by your doctor.
  • Swallow Metformin+teneligliptin as a whole with a glass of water.
  • Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Metformin+teneligliptin

Common Side Effects (Usually mild)

  • Upset stomach, nausea, or mild stomach pain
  • Diarrhoea or loose stools
  • Mild headache
  • Signs of low blood sugar, such as sweating, shaking, or dizziness (especially if taken with other diabetes medicines)


Serious Side Effects (Consult your doctor right away)

  • Severe, constant abdominal pain that spreads to your back (a sign of potential pancreas inflammation)
  • Severe or disabling joint pain
  • Signs of lactic acidosis (a rare but life-threatening buildup of acid in the blood), such as unusual muscle pain, trouble breathing, deep sleepiness, or a sudden cold feeling in your limbs
  • Severe allergic reactions, such as swelling of your face, lips, tongue, or throat, or a severe skin rash

Drug Warnings

  • Check the packaging: Make sure the blister strip is intact. Do not take the tablet if the packaging is damaged or the tablet looks different from usual.
  • Carry a quick source of sugar: Keep glucose tablets, glucose gel, or fruit juice with you, especially if you also take insulin or other medicines that may cause low blood sugar.
  • Inform your healthcare team before surgery: Tell your doctor, dentist, or surgeon that you are taking Metformin+teneligliptin before any planned procedure. They will advise whether you need to stop taking it temporarily.
  • Tell your doctor before a contrast scan: Inform your doctor if you are having an X-ray, CT scan, or another imaging test that uses an injected contrast dye. Depending on your kidney function and the type of procedure, you may need to stop Metformin+teneligliptin temporarily and restart it only after your doctor confirms that it is safe.
  • Take care when driving: Metformin+teneligliptin does not usually affect driving when taken alone. However, low blood sugar may occur when it is used with insulin or certain other diabetes medicines. Do not drive or operate machinery if you feel dizzy, shaky, weak, confused, or unable to concentrate.

Drug Interactions

The following medicines may interact with Metformin+teneligliptin and require closer monitoring or dose adjustments:

  • Other diabetes medications: Taking this medicine with insulin or sulfonylureas may increase the risk of low blood sugar.
  • Diuretics and steroids: Water pills and corticosteroids can raise your blood sugar, making this medicine less effective.
  • Beta-blockers: These blood pressure medicines can mask warning signs of low blood sugar, such as a rapid heart rate or palpitations.

Drug-Drug Interactions Checker List:

  • RIFAMPICIN
  • TETRACYCLINE
  • CLARITHROMYCIN
  • FLUCONAZOLE
  • PROBENECID
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Alcohol may increase the risk of side effects and worsen the condition.

    • Safety Warning

      Pregnancy

      caution

      Metformin+teneligliptin is a category C drug. So, it should be used only when the benefits of this medicine outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Metformin+teneligliptin should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.

    • Safety Warning

      Driving

      caution

      Metformin+teneligliptin may cause vision problems. So, do not drive or operate heavy machinery if you have any problems with your vision while using Metformin+teneligliptin.

    • Safety Warning

      Liver

      caution

      Metformin+teneligliptin should be taken with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Metformin+teneligliptin should be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      caution

      Metformin+teneligliptin is not recommended for use in children below 18 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Manage Carb Intake: Focus on complex, low-glycaemic carbohydrates like leafy greens, whole grains, and legumes to avoid sharp blood sugar spikes after meals.
    • Exercise Regularly: Aim for 150 minutes of moderate physical activity (such as brisk walking) per week. Muscle movement helps your body use insulin more efficiently.
    • Monitor Your Sugar Levels: Keep a regular log of your blood sugar levels as advised by your doctor to help track how your body responds to the medicine.
    • Limit Alcohol Consumption: Restrict alcohol intake because it can cause sudden drops in blood sugar and significantly increase your risk of lactic acidosis.

    Special Advise

    • Metformin+teneligliptin shows optimum effects when you follow healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc.
    • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose; consult your treating physician for advice.
    • Take short, frequent meals, and avoid prolonged fasting when taking this drug. Beware of hypoglycemia symptoms, including sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and also get in touch with your physician. Make sure to carry these with you at all times, especially for long travels.
    • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycemia (a decrease in blood sugar, which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, which impacts various organs in the body).

    Patients Concern

    Disease/Condition Glossary

    Type 2 diabetes mellitus: It is a chronic condition in which blood glucose levels are elevated in the body. Insulin is responsible for the utilisation of glucose by the cells. In type 2 diabetes, the body cells do not respond to insulin, or in later stages, the body may not produce enough insulin. Symptoms include excessive thirst, excessive hunger, fatigue, increased appetite and dry mouth. This condition may worsen over time and cause toxic effects if not properly treated.

    FAQs

    Metformin+teneligliptin is used to treat Type 2 diabetes mellitus. It improves glycaemic control in diabetic patients who do not react well to Metformin alone.

    Metformin+teneligliptin is a combination of two antidiabetic medicines, Metformin and Teneligliptin. It works by increasing insulin production, helping to restore your body's appropriate response to insulin, especially in muscle and fatty tissues, thereby lowering your elevated blood sugar levels.

    Hypoglycemia refers to low blood glucose levels. Metformin+teneligliptin may cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, engage in intense exercise, or take other antidiabetic medicine along with this medicine. So, take your medicine as advised by your doctor to avoid any unwanted effects of this medicine.

    If you feel that your blood sugar levels are dropping, eat glucose tablets or chocolate immediately. This will help to increase your sugar levels instantly. So, it is always advised to carry glucose tablets or sugar candies with you.

    Yes, Metformin+teneligliptin is safe to use if taken in the dose and duration prescribed by the doctor.

    Metformin+teneligliptin may cause nausea and vomiting as side effects. Consume bland food and water, avoid foods with strong smells, spicy food, caffeine, alcohol and carbonated drinks.

    Metformin+teneligliptin is contraindicated in people who are allergic to any of its components, patients having severe ketoacidosis, diabetic coma or pre-coma, type 1 diabetes, severe infection, severe trauma and severe external injury and in patients with a history of lactic acidosis.

    Metformin+teneligliptin can cause lactic acidosis, a rare but serious metabolic complication. Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.

    Long-term use of Metformin+teneligliptin may lead to vitamin B12 deficiency as Metformin+teneligliptin might interfere with the absorption of vitamin B12. Consult the doctor if you experience symptoms of vitamin B12 deficiency like tingling sensations and numbness in hands and feet, urinary problems, weakness, change in mental status and difficulty in maintaining balance.

    Store Metformin+teneligliptin at room temperature, in a dry place. Keep it out of sight and reach of children.

    Metformin+teneligliptin is not recommended during pregnancy as its safety in pregnant women is unknown. Contact the doctor if you are pregnant, planning for pregnancy or think you may be pregnant.

    Metformin+teneligliptin is not recommended for nursing mothers as this medicine may get secreted in the breast milk and cause unwanted effects in the nursing babies. Contact the doctor if you are breastfeeding.

    Metformin+teneligliptin is not recommended for use in children below 18 years of age.

    Overdose of Metformin+teneligliptin might cause lactic acidosis. Symptoms of lactic acidosis may include nausea, vomiting, and weakness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

    Side effects of Metformin+teneligliptin include nausea, vomiting, diarrhoea, headache, stomach ache, respiratory infection, weight gain, sweating, palpitations, and vision problems. Consult the doctor if any of the side effects persist or worsen.

    Consult the doctor if you have severe joint pain after taking Metformin+teneligliptin. The doctor might ask you to discontinue the medicine if appropriate.

    Take Metformin+teneligliptin with or after a meal unless your doctor advises otherwise. Taking it with food may help reduce nausea, stomach discomfort, and other digestive side effects. Contact your doctor if these symptoms continue or become difficult to manage.

    Metformin+teneligliptin is generally considered weight-neutral, meaning it usually does not cause significant weight gain. However, changes in weight may vary between individuals. Continue following the diet and physical activity plan recommended by your healthcare team.

    Type 2 diabetes usually requires long-term treatment. Continue taking Metformin+teneligliptin for as long as your doctor recommends, even if you feel well, because high blood sugar may not cause noticeable symptoms. Do not stop taking the medicine without consulting your doctor.

    If you are pregnant, planning a pregnancy, or breastfeeding, consult your doctor before taking Metformin+teneligliptin. Your doctor will recommend the most suitable treatment based on your blood sugar levels and individual health needs.

    Metformin+teneligliptin does not usually affect the ability to drive. However, low blood sugar may occur when it is taken with insulin or certain other diabetes medicines. Do not drive if you feel dizzy, shaky, weak, confused, or unable to concentrate.

    No. Metformin+teneligliptin helps control blood sugar but does not cure type 2 diabetes. Taking the medicine regularly and following your recommended diet, physical activity, and blood sugar monitoring plan can help manage the condition and reduce the risk of complications.

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