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About METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE

METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE is a combination medication indicated for the management of neuropathic pain. It may also be used to treat pain caused by fibromyalgia (musculoskeletal pain), nerve pain in post-herpetic neuralgia (damage to the nerve fibres during shingles infection) or spinal cord injury. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. 

METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE contains Methylcobalamin, Pregabalin, Alpha lipoic acid, and Pyridoxine. Mecobalamin/Methylcobalamin, a form of vitamin B12, regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Pregabalin is an antiepileptic agent that works by binding to the specific site on voltage-gated calcium channels, thus helping to relieve nerve pain. Alpha-lipoic acid is an antioxidant that prevents cell damage and restores vitamin levels in the body. It also decreases pain and numbness in neuropathy. Pyridoxine (vitamin B6) is a water-soluble vitamin that is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters. 

Your doctor will decide the dosage based on your medical condition. Sometimes, METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE may have common side effects like dizziness, drowsiness, blurred vision, shakiness, headache, nausea, vomiting, constipation, weight gain, swelling in the hands and feet, and dry mouth. These side effects do not require medical attention and gradually resolve over time. However, talk to your doctor if you experience these side effects persistently.

Please tell your doctor if you are allergic to METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE or its components. It is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE as it could lead to increased dizziness and sleepiness. METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE should be used in children only with the doctor's advice.

Uses of METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE

Neuropathy, pain in fibromyalgia (musculoskeletal pain), and nerve pain in post-herpetic neuralgia (damage to the nerve fibres during shingles infection).

Medicinal Benefits

METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE contains Methylcobalamin, Pregabalin, Alpha lipoic acid, and Pyridoxine. Methylcobalamin regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Pregabalin works by binding to the specific site on voltage-gated calcium channels, thus helping to relieve nerve pain. Alpha-lipoic acid decreases pain and numbness in neuropathy. It helps lower blood sugar levels and protects the nerves from damage in diabetic neuropathy. Pyridoxine is involved in the formation of red blood cells and neurotransmitters. It also relieves nerve pain and corrects the nerve impulse transmission process.

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE

  • Dizziness
  • Drowsiness
  • Blurred vision
  • Shakiness
  • Headache
  • Nausea
  • Vomiting
  • Constipation
  • Weight gain
  • Swelling in the hands and feet
  • Dry mouth 

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you have any blood disorders, chronic obstructive pulmonary disease (COPD), liver/kidney/heart diseases, diabetes, mood disorders, substance use disorder, and angioedema (painless swelling under the skin) before starting METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE. Pregnant and breastfeeding women should consult their doctor before taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE. This medicine may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol during the treatment, as it could increase dizziness and sleepiness. METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE should be used in children only with the doctor's advice.

Drug Interactions

Drug-Drug Interaction: METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE may interact with painkillers (codeine, hydrocodone), anti-anxiety drugs (diazepam, alprazolam), muscle relaxants (carisoprodol, cyclobenzaprine), anti-allergic drugs (cetirizine), common cold medicines (diphenhydramine), and antipsychotics (olanzapine, quetiapine).

Drug-Food Interaction: Avoid consumption of alcohol while taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE as it might cause increased dizziness and sleepiness.

Drug-Disease Interaction: Inform your doctor if you have liver/kidney/heart diseases, chronic obstructive pulmonary disease (COPD), diabetes, mood disorders, substance use disorder, and angioedema before starting METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE.

Drug-Drug Interactions Checker List:

  • CODEINE
  • HYDROCODONE
  • DIAZEPAM
  • ALPRAZOLAM
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • OLANZAPINE
  • QUETIAPINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol while taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE as it may cause increased dizziness and sleepiness.

    • Safety Warning

      Pregnancy

      caution

      METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE should be used in pregnancy only if prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE.

    • Safety Warning

      Breast Feeding

      caution

      Pyridoxine is excreted into the breast milk. Please consult your doctor before taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE if you are a nursing mother.

    • Safety Warning

      Driving

      unsafe

      METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE causes dizziness, drowsiness, and blurred vision and may interfere with your driving ability. Do not drive or operate machinery if you are not mentally alert and focused.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases before taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE. Dose adjustments may be necessary.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases before taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE. Your doctor may adjust the dose based on your condition.

    • Safety Warning

      Children

      caution

      METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE should be used in children only when a doctor advises. The doctor will prescribe the dosage based on the child's age and weight.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Try Vitamin B complex food sources like milk, cheese, eggs, liver and kidney, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables, such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpeas.
    • Include cayenne pepper in your diet to help lower neuropathic pain.
    • Taking a warm shower can help ease the pain.
    • Avoid smoking and alcohol consumption.
    • Using essential oils for massage can help increase circulation.
    • Exercise regularly and maintain a healthy lifestyle. Avoid excess fatty foods.

    Special Advise

    Let your doctor and the laboratory staff know if you are using METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE since Pyridoxine may interfere with a urine test for urobilinogen. 

    Patients Concern

    Disease/Condition Glossary

    Neuropathic pain: It is a nervous disorder that occurs due to nerve damage caused by chronic progressive nerve disease, limb amputation, diabetes or due to infection or injury. The pain could be intermittent or continuous, such as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensation is also common with neuropathic pain. Symptoms include spontaneous, un-triggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful). 

    Fibromyalgia: It is a condition characterized by widespread musculoskeletal pain and tenderness. It usually occurs along with fatigue and altered sleep, memory and mood. Symptoms include fatigue, joint stiffness, tingling, numbness, a burning or prickling sensation in hands and feet, and mood swings.

    FAQs

    How does METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE work?

    METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE affects the chemicals in the brain that send pain signals to the nervous system, thereby relieving nerve pain. It also reduces further nerve damage in neuropathy and aids in nerve regeneration.

    What should I know before using METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE?

    People taking METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE should be closely monitored for suicidal thoughts or behaviour. Do not hesitate to speak with your doctor immediately if you experience suicidal tendencies.

    Does METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE cause any abnormal test results?

    Pyridoxine in METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE may interfere with a urine test for urobilinogen. Please ensure your doctor and the laboratory staff know you take METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE before undergoing blood and urine examinations.

    Available Medicines for

    METHYLCOBALAMIN+PREGABALIN+ALPHA LIPOIC ACID+PYRIDOXINE