Metoclopramide+paracetamol
About Metoclopramide+paracetamol
Metoclopramide+paracetamol is used to treat signs of migraine such as headache, being sick (vomiting), and feeling sick (nausea). Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which generally occurs on one side of the head; however, it can occur on both sides or shift.
Metoclopramide+paracetamol is a combination of two drugs: Metoclopramide (anti-emetics) and Paracetamol (analgesics). Metoclopramide works on the part of the brain and prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, which helps empty the stomach. Paracetamol works by blocking the effect of a chemical messenger known as prostaglandins, which cause pain. Together, Metoclopramide+paracetamol helps relieve the symptoms of migraine.
Take Metoclopramide+paracetamol as prescribed. You are advised to take Metoclopramide+paracetamol as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as dizziness, sleepiness, diarrhoea, irregular periods, weakness, nervousness and breast enlargement in men. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor before taking Metoclopramide+paracetamol if you are pregnant or breastfeeding. Metoclopramide+paracetamol should not be taken during the first 6 months of pregnancy. Metoclopramide+paracetamol may cause drowsiness and sleepiness, so drive with caution. Metoclopramide+paracetamol is not recommended for children below 18 years as safety and efficacy have not been established. Avoid consuming alcohol with Metoclopramide+paracetamol as it could lead to increased drowsiness and sleepiness. Inform your doctor about your health condition and medicines you are taking to rule out unpleasant side effects.
Uses of Metoclopramide+paracetamol
Medicinal Benefits
Metoclopramide+paracetamol offers several important benefits that help provide faster and more complete relief from migraine attacks:
- Dual-Action Symptom Relief: It treats both migraine pain and associated nausea in a single medicine, reducing the need for multiple medications.
- Faster Pain Relief: By improving stomach emptying, it helps the pain-relieving medicine absorb more quickly, allowing faster relief from migraine symptoms.
- Reduces Nausea and Vomiting: It settles the stomach and helps prevent vomiting, ensuring the medicine remains in your body long enough to work effectively.
- Shortens Migraine Recovery: By relieving both headache and digestive symptoms at the same time, it helps you recover more quickly and return to your normal activities sooner.
Directions for Use
- Metoclopramide+paracetamol can be taken with or without food as advised by the doctor.
- Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
- Swallow Metoclopramide+paracetamol as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Metoclopramide+paracetamol
Common Side Effects (Usually mild):
- Sleepiness or drowsiness
- Feeling restless or anxious
- Mild diarrhoea or stomach upset
- Lack of energy or physical weakness
Serious Side Effects (Call a doctor right away):
- Involuntary, uncontrolled muscle movements or twitching, especially in your face, tongue, or limbs
- Yellowing of the eyes or skin, dark urine, or severe upper stomach pain (signs of liver damage)
- Sudden breathing difficulties, swelling of your face, lips, tongue, or throat (signs of a severe allergic reaction)
- Extremely high fever, stiff muscles, or a rapid, irregular heartbeat
Medicines Containing this Salt
View AllDrug Warnings
- Check Other Medicines for Paracetamol: Always check the labels of any other cold, flu, cough, or pain relief medications you are taking to ensure they do not contain the same pain-relieving ingredient, as combining them can cause severe liver damage.
- Avoid Driving Until You Know Its Effects: Do not drive, operate heavy machinery, or perform hazardous activities after taking this medicine until you know how it affects you, as it can cause significant drowsiness.
- Avoid Alcohol: Limit or completely avoid alcohol consumption while using this medicine, because alcohol increases the risk of liver damage and intensifies drowsiness.
- Do Not Use for Longer Than Recommended: Avoid using this medicine for more than a few consecutive days without consulting your doctor, as long-term use can increase the risk of serious, involuntary muscle disorders.
- Inform Healthcare Providers Before Procedures: If you are scheduled for any surgical or dental procedures, tell your healthcare provider that you are currently taking Metoclopramide+paracetamol.
Drug Interactions
Here are the medicines that may interact with Metoclopramide+paracetamol and increase the risk of side effects or reduce treatment effectiveness:
- Other pain relievers: Combining this medicine with other products containing the same painkiller can lead to an accidental overdose and severe liver damage.
- Sedatives and sleep aids: Taking this medicine with tranquillizers, sleeping pills, or opioid pain medications can cause dangerous levels of drowsiness and slowed breathing.
- Parkinson's medications: Some treatments for Parkinson's disease may become less effective when taken alongside Metoclopramide+paracetamol.
- Blood thinners: Long-term or regular use of the pain-relieving component in this medicine may increase the risk of bleeding when taken with medications like warfarin.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Metoclopramide+paracetamol as it may cause increased sleepiness.
Pregnancy
unsafeMetoclopramide+paracetamol should not be taken during the first 6 months of pregnancy. Please consult your doctor before taking Metoclopramide+paracetamol if you are pregnant or planning for pregnancy.
Breast Feeding
cautionMetoclopramide+paracetamol may pass into breastmilk. Please consult your doctor before taking Metoclopramide+paracetamol if you are breastfeeding.
Driving
cautionMetoclopramide+paracetamol may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
safe if prescribedUse Metoclopramide+paracetamol in children only if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
- Rest in a dark room: At the first sign of a migraine, lie down in a quiet, dark, and cool room to help reduce the intensity of the headache.
- Stay hydrated: Drink small, frequent sips of water throughout the day. Dehydration is a common trigger for both migraines and nausea.
- Avoid trigger foods: Keep a food diary to identify and avoid personal dietary triggers, which often include aged cheeses, artificial sweeteners, caffeine, and processed foods.
- Eat small, frequent meals: If you are prone to delayed stomach emptying, eating smaller portions of easily digestible food can prevent stomach discomfort and support proper digestion.
- Manage stress levels: Practice relaxation techniques such as deep breathing, meditation, or gentle stretching, as stress is one of the most frequent triggers for migraine attacks.
Special Advise
- Metoclopramide in Metoclopramide+paracetamol may decrease the gastric absorption of digoxin. Therefore, inform your doctor if you take digoxin.
Patients Concern
Disease/Condition Glossary
Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. Warning symptoms precede migraine headache one or two days before the headache itself. The warning symptoms include food cravings, depression, fatigue, hyperactivity, irritability and neck stiffness. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light.
FAQs
Metoclopramide+paracetamol is used to treat signs of migraine such as headache, being sick (vomiting), and feeling sick (nausea).
Metoclopramide+paracetamol contains Metoclopramide and Paracetamol. Metoclopramide works on the part of the brain, thereby prevents the symptoms of nausea and vomiting. It also works on the muscles in the upper part of the digestive system, this helps in emptying the stomach. Paracetamol works by blocking the effect of a chemical messenger known as prostaglandins which cause pain. Thereby, helps in relieving pain.
Consult your doctor before taking oral contraceptive pills along with Metoclopramide+paracetamol as they might decrease the effectiveness of Metoclopramide+paracetamol. Talk to your doctor, he/she may advise you to use an alternate method of contraception.
Metoclopramide+paracetamol contains Paracetamol, an analgesic used to provide relief from pain. Therefore, please consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Metoclopramide+paracetamol as they may also contain paracetamol.
If you had an operation on your stomach or intestine, do not take Metoclopramide+paracetamol during the first 3-4days after the surgery. However, please talk to your doctor before taking Metoclopramide+paracetamol if you have had surgery.
Diarrhoea could be a side-effect of Metoclopramide+paracetamol. Drink plenty of liquids to replace the lost fluids if you experience diarrhoea. Consult your doctor if the condition persists or worsens.
Metoclopramide+paracetamol may cause irregular periods or loss of periods. Please consult your doctor if you experience this for longer than a few days.
Metoclopramide+paracetamol contains metoclopramide, which can cause side effects like drowsiness and dizziness. Therefore, avoid giving Metoclopramide+paracetamol before a task that requires mental focus such as running, jogging or cycling, or any other sports activity.
Metoclopramide+paracetamol can enter the brain and can cause serious side effects including unusual mood changes such as anxiety, depression or agitation and uncontrolled and repeated movements of the arms, legs, eyes, mouth, tongue, face and jaw. If you experience any of these side effects, stop taking Metoclopramide+paracetamol and consult your doctor immediately.
Metoclopramide+paracetamol is not recommended for use in patients who are allergic to Metoclopramide+paracetamol, who have stomach or digestive tract bleeding, intestinal blockage, recent stomach or intestine surgery, phaeochromocytoma (a rare tumour of the adrenal gland) or epilepsy.
Children who are malnourished, who are suffering from liver/kidney disease, heart disease, electrolyte disturbances, antipsychotic medications, or atopic allergies, should consult your doctor before taking Metoclopramide+paracetamol.
Overdose of Metoclopramide+paracetamol may make your child feel dizzy, sleepy or drowsy, confused, sweaty, vomit, have pain in the stomach, have convulsions or fits, or experience uncontrolled muscle movements or notice yellowing of the skin. If you notice these symptoms, please consult your doctor immediately.
Store Metoclopramide+paracetamol at temperature not exceeding 25°C, protect from sunlight. Keep out of reach of children.
You are recommended to consult your doctor before taking other medicines with Metoclopramide+paracetamol to avoid possible interactions.
The common side effects of Metoclopramide+paracetamol are dizziness, restlessness, fatigue, drowsiness, diarrhoea, and weakness. If any of these side effects persist or worsen, please consult your doctor.
No, this medicine is not designed to prevent migraines from occurring. It is meant to treat active symptoms once a migraine attack has already started. Talk to your doctor for options on daily preventative treatments.
It is highly recommended to avoid alcohol while taking this medicine. Alcohol significantly increases the risk of severe liver damage and can make the drowsiness caused by the medicine much worse. Talk to your doctor about your alcohol intake.
You should only use this medicine during pregnancy if your doctor has specifically advised you to do so. Some components of this medicine may carry risks to the developing baby depending on the stage of pregnancy. Talk to your doctor to discuss safer alternatives.
If you vomit shortly after taking the tablet, do not immediately take another dose, as you cannot be sure how much of the medicine was already absorbed. Taking another tablet too soon could lead to an accidental overdose. Talk to your doctor or pharmacist for guidance on what to do.
Using this medicine long-term can lead to serious, sometimes permanent, involuntary muscle movements and may also cause medication-overuse headaches. It is strictly meant for short-term, occasional use during active migraine attacks. Talk to your doctor if your migraines are frequent.
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