Don't stop taking NEBIVOLOL+AMLODIPINE without talking to your doctor first. Stopping NEBIVOLOL+AMLODIPINE abruptly may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use NEBIVOLOL+AMLODIPINE if you have a very slow heartbeat, asthma, serious heart condition (sick sinus syndrome), or any heart blockage. It should not be given to children less than 12 years of age. Before taking NEBIVOLOL+AMLODIPINE you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder, adrenal gland cancer, or problems with circulation (Raynaud’s syndrome).

Drug-Drug Interaction: NEBIVOLOL+AMLODIPINE may have interaction with other beta-blockers (atenolol, bisoprolol, carteolol, esmolol, metoprolol, or sotalol), other anti-hypertensive drugs (aliskiren, amiloride, enalapril, captopril, quinapril, diltiazem), asthma medications (theophylline, aminophylline), potassium-rich supplements, pain killers (ibuprofen, aspirin), medicines to treat anxiety disorder (alprazolam and diazepam).

Drug-Food Interaction: NEBIVOLOL+AMLODIPINE is known to interact with grapefruit and protein-enriched foods. Using NEBIVOLOL+AMLODIPINE together with ayurvedic, homoeopathy, Unani, herbal supplements, or any other OTC items may decrease the effects of NEBIVOLOL+AMLODIPINE. Hence, it is better to maintain at least 2 hours gap between the administration of NEBIVOLOL+AMLODIPINE and these products. 

Drug-Disease Interaction: NEBIVOLOL+AMLODIPINE may have interactions with diabetes, liver impairment, high cholesterol, hyperthyroidism, psoriasis, kidney impairment, asthma, heart problems such as bradyarrhythmia, cardiogenic shock, low blood pressure, fast heart rate, ischemic heart disease, and congestive heart failure.

• Keep your weight under control with BMI (Body Mass Index) 19.5-24.9.
• Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
• Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
• If you are taking alcohol, then only one serving for women and two servings is advisable.
• Quitting smoking is the best strategy to lower the risk of heart disease.
• Avoid chronic stress, as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
• Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
• Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil can help in lowering your elevated blood pressure.

• Regularly monitor blood pressure levels to prevent hypotension (low blood pressure).
• Get up slowly while rising from lying or sitting position as NEBIVOLOL+AMLODIPINE may cause dizziness.
• Keep your doctor informed about your health/disease conditions and the medicines you are taking.
• To treat your condition effectually, continue taking NEBIVOLOL+AMLODIPINE for as long as your doctor has prescribed it. Try not to stop taking it on your own as it may suddenly increase blood pressure, chest pain, or heart attack.  
• Your doctor may advise you to get a regular kidney function test and potassium levels in the body while taking NEBIVOLOL+AMLODIPINE.