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compositionComposition:AMLODIPINE-5MG+NEBIVOLOL-5MG
prescription
Prescription Medicine
info
Nebykare AM Tablet 10's
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

AMLODIPINE-5MG+NEBIVOLOL-5MG

Manufacturer/Marketer :

4Care Lifesciences Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Nebykare AM Tablet

Nebykare AM Tablet is a prescription medication primarily used to treat high blood pressure (hypertension). By lowering elevated blood pressure, it helps reduce your risk of suffering from serious cardiovascular complications, such as heart attacks or strokes.

To get the best results, you must take Nebykare AM Tablet regularly every day, exactly as your doctor has prescribed. You can take this medication with or without food, but it is highly recommended to take it at the same time each day to build a consistent routine. Combining this treatment with a heart-healthy diet low in salt, regular physical exercise, and maintaining a healthy weight will greatly support your blood pressure management.

Some people may experience mild side effects, such as headaches, dizziness, or mild swelling in the ankles. If you experience serious side effects, such as a very slow heart rate, worsening chest pain, or severe dizziness, you must contact your doctor right away.

Do not take this if you have severe heart failure, extremely slow heart rate, cardiogenic shock, or certain severe heart block conditions. Before starting this medication, talk to your doctor if you have a history of liver damage, kidney disease, asthma, or blood circulation problems.

This medicine can interact with other drugs, alcohol, and tobacco. For instance, drinking alcohol while taking this tablet can cause a sudden, severe drop in your blood pressure, leading to dizziness or fainting. Pregnant, breastfeeding, or elderly individuals should consult their doctor before starting this medication to ensure it is safe for their specific situation.

Uses of Nebykare AM Tablet

Nebykare AM Tablet is used to treat high blood pressure. The detailed uses of Nebykare AM Tablet are as follows:

  • High blood pressure (hypertension): Nebykare AM Tablet helps lower elevated blood pressure, reducing the workload on your heart and lowering your long-term risk of cardiovascular events like stroke or heart attack.

Key Benefits

Nebykare AM Tablet helps maintain healthy blood pressure levels, supporting the proper functioning of the heart and blood vessels. By keeping blood pressure under control, it helps protect vital organs and promotes long-term cardiovascular health. Benefits may include:

  • Helps maintain healthy blood flow and reduces strain on the heart.
  • Supports the protection of vital organs such as the heart, brain, and kidneys.
  • Reduces the risk of complications associated with uncontrolled high blood pressure.
  • Simplifies treatment by combining two blood pressure medicines in a single tablet.
  • Supports consistent blood pressure management and long-term cardiovascular well-being.
Side effects of Nebykare AM Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

Always take this medication exactly as directed by your healthcare provider. Follow these simple steps for safe use:

  • Swallow the tablet whole with a glass of water.
  • Do not crush, chew, or break the tablet, as this can alter how the medicine is released into your body.
  • Take the tablet at the same time every day, either with or without food.
  • Never adjust your dose or stop taking this medicine without first consulting your doctor.

How Nebykare AM Tablet Works

Nebykare AM Tablet contains Nebivolol and Amlodipine. • Nebivolol: It helps lower blood pressure by slowing the heart rate and reducing the workload on the heart. It also helps the blood vessels relax, allowing blood to flow more easily. • Amlodipine: It helps relax and widen the blood vessels, reducing resistance to blood flow. This helps lower blood pressure and improves circulation throughout the body.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Nebykare AM Tablet to avoid unpleasant side-effects.

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Pregnancy

Consult your doctor

It is advised to consult your doctor if you plan to conceive or are already pregnant before starting Nebykare AM Tablet .

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Breast Feeding

Consult your doctor

Please consult your doctor before taking Nebykare AM Tablet if you are breastfeeding; your doctor will prescribe you Nebykare AM Tablet only if the benefits outweigh the risks.

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Driving

Caution

Nebykare AM Tablet may cause dizziness and weakness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Nebykare AM Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Nebykare AM Tablet to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Nebykare AM Tablet should not be used by children, as the efficacy and safety have not been established.

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Heart

Safe if prescribed

Nebykare AM Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Nebykare AM Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Nebykare AM Tablet

If you suspect an overdose, seek immediate emergency medical attention. An overdose can cause an extremely slow heart rate, severe dizziness, and a dangerous drop in blood pressure.

Diet & Lifestyle Advise

  • Reduce sodium intake: Lowering the amount of salt in your diet directly helps lower your blood pressure and reduces fluid retention.
  • Eat potassium-rich foods: Incorporate vegetables and fruits like leafy greens, bananas, and avocados into your diet, unless your doctor advises otherwise.
  • Exercise regularly: Aim for at least 150 minutes of moderate physical activity, such as brisk walking, every week.
  • Limit alcohol: Avoid or significantly limit alcohol consumption to prevent sudden blood pressure drops and increased dizziness.
  • Avoid tobacco: Smoking damages your blood vessels and raises your cardiovascular risk; quitting smoking will greatly support your blood pressure treatment.

Have a query?

How Soon It Starts Working

  • The time required for Nebykare AM Tablet to start to work: Nebykare AM Tablet ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Nebykare AM Tablet last: The effect of Nebykare AM Tablet lasts for 24 hours.

What if you forget to take Nebykare AM Tablet

If you miss a dose of Nebykare AM Tablet , take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Inspect the medicine before use: Do not take the tablets if the packaging is damaged or if the tablets appear discolored, broken, or altered.
  • Change positions slowly: Stand up gradually from a sitting or lying position to help prevent dizziness and reduce the risk of falls.
  • Do not stop treatment abruptly: Continue taking Nebykare AM Tablet as prescribed, as suddenly stopping the medicine may cause a rapid rise in blood pressure or worsen chest pain.
  • Monitor your heart rate regularly: Check your pulse as advised by your doctor and seek medical advice if your resting heart rate falls below 50 beats per minute.
  • Inform healthcare providers before procedures: Tell your dentist, surgeon, or other healthcare professionals that you are taking Nebykare AM Tablet before undergoing any medical or dental procedure.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Other heart rate-lowering medications (e.g., digoxin, amiodarone): May increase the risk of an abnormally slow heart rate.
  • Other blood pressure medications: Can cause an additive effect, lowering your blood pressure too much.
  • Nonsteroidal anti-inflammatory drugs (e.g., ibuprofen): May reduce the effectiveness of Nebykare AM Tablet and raise blood pressure.

Drug-Food Interactions

  • Grapefruit and grapefruit juice: May increase the levels of amlodipine in your body, increasing the risk of side effects like severe dizziness and swelling.

Drug-Disease Interactions

  • Liver disease: Patients with liver impairment should use Nebykare AM Tablet cautiously, as reduced liver function may cause the medicine to accumulate in the body and increase the risk of side effects.
  • Asthma or chronic lung disease: The beta-blocker component of Nebykare AM Tablet may worsen breathing problems or trigger asthma symptoms in susceptible individuals.
  • Severe heart block: Do not take Nebykare AM Tablet if you have serious electrical conduction problems in the heart, as it may further slow the transmission of heart signals and worsen the condition.
Nebivolol + AmlodipineTheophylline
Severe
Nebivolol + AmlodipinePrimidone
Severe

Drug-Drug Interactions

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Nebivolol + AmlodipineTheophylline
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Nebivolol with Theophylline may reduce the effect of Nebivolol.

How to manage the interaction:
Taking Nebivolol with Theophylline together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, or difficulty breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Nebivolol + AmlodipinePrimidone
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Amlodipine and Primidone together may lower Amlodipine blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Amlodipine with Primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Nebivolol + AmlodipineDisopyramide
Severe
How does the drug interact with Nebykare AM Tablet:
Taking Disopyramide and Nebivolol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Disopyramide and Nebivolol together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, shortness of breath, chest pain, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Nebivolol + AmlodipineSimvastatin
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Simvastatin with Amlodipine may result in considerably higher blood levels of Simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Amlodipine with Simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, consult the doctor if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
Nebivolol + AmlodipineEnzalutamide
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Amlodipine and Enzalutamide may lower Amlodipine blood levels, making the medicine less effective.

How to manage the interaction:
Taking Amlodipine with Enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
Nebivolol + AmlodipineCarbamazepine
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Amlodipine and Carbamazepine together may significantly reduce amlodipine blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Amlodipine with Carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
Nebivolol + AmlodipineRitodrine
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Nebivolol and Ritodrine may decrease the effect of Nebivolol. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Nebivolol and Ritodrine together can possibly result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
Nebivolol + AmlodipineDolasetron
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Dolasetron together with Amlodipine can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Amlodipine and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
Nebivolol + AmlodipineTizanidine
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Tizanidine and Amlodipine can increase the risk or severity of developing side effects like low blood pressure.

How to manage the interaction:
Although co-administration of Amlodipine with Tizanidine can result in an interaction, it can be taken when a doctor has advised it. However, if you experience headache, dizziness, palpitations, or irregular heart rate while taking these drugs, contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
Nebivolol + AmlodipineClonidine
Severe
How does the drug interact with Nebykare AM Tablet:
Co-administration of Clonidine and Nebivolol together may lower blood pressure and slow your heart rate.

How to manage the interaction:
Taking Clonidine and Nebivolol together can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+NEBIVOLOL-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+NEBIVOLOL-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit, Grapefruit Juice

How to manage the interaction:
Consumption of grapefruit and grapefruit juice with Nebykare AM Tablet the levels of Nebykare AM Tablet in your bloodstream may drop. Avoid consuming a lot of grapefruit juice and grapefruit when using Nebykare AM Tablet, instead, take it with water. As a result, your body will absorb the drug more easily.

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FAQs

Nebykare AM Tablet is used to treat hypertension (high blood pressure).

Nebykare AM Tablet contains Amlodipine (calcium channel blocker) and Nebivolol (beta-blocker); primarily used to treat high blood pressure.‚ Amlodipine works by‚ relaxing the blood vessels. Nebivolol acts by‚ relaxing‚ and widening‚ the blood vessels making it easier for the heart to pump blood to all parts of the body. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.

Your doctor may probably tell you to stop taking Nebykare AM Tablet as it lowers blood pressure (hypotension) when combined with general anaesthesia before surgery. So, please inform your doctor before surgery if you are taking Nebykare AM Tablet .

Mild ankle swelling is a known side effect of amlodipine. Try elevating your legs when sitting and avoid standing for long periods. If the swelling is painful, sudden, or worsens significantly, talk to your doctor.

If you have diabetes, you should monitor your blood glucose levels often as Nebykare AM Tablet might mask hypoglycemia symptoms (low glucose levels). However, please consult your doctor before taking Nebykare AM Tablet if you have diabetes.

If you have hyperthyroidism (overactive thyroid), you should monitor your condition regularly as Nebykare AM Tablet might mask hyperthyroidism symptoms such as abnormally fast heart rate. However, please consult your doctor before taking Nebykare AM Tablet if you have hyperthyroidism.

Do not overdose on Nebykare AM Tablet or any medicine, which could lead to very unpleasant side effects. Take Nebykare AM Tablet only as prescribed by your doctor. An overdose of Nebykare AM Tablet can cause a very slow heartbeat, low blood pressure, breathlessness, and acute heart failure. Rush to your nearest doctor as early as possible if you have overdosed on Nebykare AM Tablet .

If you miss a dose of Nebykare AM Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

Nebykare AM Tablet may cause side effects such as headache, ankle swelling, slow heart rate, tiredness, constipation or cold extremities (cold hands and feet). If these side effects persist or worsen, please consult your doctor.

No, this medication is generally not recommended during pregnancy as it can reduce blood flow to the unborn baby. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor immediately.

No, you should never stop taking this medication abruptly. High blood pressure is a chronic condition, and stopping the medicine can cause your blood pressure to jump back up quickly, increasing your risk of a heart attack or stroke. Talk to your doctor.

You should limit or avoid alcohol. Drinking alcohol while taking this medicine can cause your blood pressure to drop suddenly, leading to severe dizziness, headaches, or fainting. Talk to your doctor.

Nebykare AM Tablet begins to lower your blood pressure within a few hours of the first dose. However, it can take up to 2 to 4 weeks of regular use to see the full therapeutic effect. Talk to your doctor if your blood pressure remains high.

Yes, dizziness and fatigue are common when starting this medication or when your dose is being adjusted. Avoid driving, climbing, or operating heavy machinery until you know how this medicine affects you. Talk to your doctor if these symptoms persist.

You can take Nebykare AM Tablet at either time, but it is best to take it at the exact same time every day to keep a steady level of medicine in your body. Many patients find it easiest to take in the morning. Talk to your doctor.

Pain relievers like ibuprofen or naproxen (NSAIDs) can make Nebykare AM Tablet less effective at lowering your blood pressure and can impact kidney function. Paracetamol is generally a safer alternative, but you should always talk to your doctor or pharmacist first.

Disclaimer

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Reference

  1. Electronic Medicines Compendium (EMC). Pil.9966 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. U.S. Food and Drug Administration (FDA). 021742S013Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026] Check here
  3. Drugs.com Clinical Review Team. Nebivolol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  4. National Health Service (NHS). Amlodipine - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  5. Drugs.com Clinical Review Team. Amlodipine Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  6. Amlodipine besylate [Prescribing Information]. 2011. [Accessed on 11 Apr. 2019] Check here
  7. Nebivolol and Amlodipine [Summary of Product Characteristics]. 2020. [Accessed on 16 Sep. 2024]Check here

Country of origin

India

Manufacturer/Marketer address

BF, 2nd Floor, Sumeru Complex, Opp Karnavati Pagarkha Bazar, Nr. Parimal Underpass, Paldi, Ahmedabad, Gujarat, 380058
Other Info - NEB0238

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