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About NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL

NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL belongs to the class of medications called ‘analgesics’ used to treat mild to moderate pain. It can relieve pain, swelling, and inflammation associated with various chronic (long-term) conditions, such as rheumatoid arthritis (joint pain, especially in the hands and feet) and osteoarthritis (joint pain, especially in the knees, hip, hands, neck, and lower back). It can also relieve acute (short-term) pain such as toothache, ear pain, throat pain, muscle ache, and backache.

NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL is a combination medicine that contains Nimesulide, Paracetamol, and Serratiopeptidase. Nimesulide and Paracetamol are pain killers. They can also reduce fever and inflammation. They act by blocking the action of chemical messengers responsible for pain, fever, and inflammation. On the other hand, Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation and promotes healing.

NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL is available in the form of a tablet. It would be best if you took this NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL precisely as prescribed by your doctor. NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may cause side effects such as nausea, vomiting, indigestion, stomach pain, headache, heartburn, and diarrhoea. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a doctor immediately.

Do not take NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL if you are allergic to any of its contents. NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL should not be used in patients with liver failure, severe kidney failure, heart failure, gastric ulcers, bleeding disorders, and alcohol or drug abuse. Before taking NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL, inform your doctor if you are pregnant or breastfeeding. NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL should not be given to children below 12 years of age. In elderly people, NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may be given with caution. Alcohol should not be taken while using NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL as it further increases the risk of liver damage. NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may not affect your ability to drive. However, do not drive or operate heavy machinery if you feel dizzy.

Uses of NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL

Mild to moderate pain

Medicinal Benefits

NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL is a combination medicine that contains Nimesulide, Paracetamol, and Serratiopeptidase. Nimesulide is a non-steroidal anti-inflammatory drug (NSAID). Paracetamol is an analgesic and antipyretic. Both medicines can reduce pain and fever. They act by blocking the action of chemical messengers responsible for pain, fever, and inflammation. Serratiopeptidase is an enzyme. It causes thinning of the fluids around the damaged tissue, thereby making fluid drainage easier in the swollen tissue. This effect reduces swelling and promotes faster healing. Together, NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL can effectively reduce pain, swelling, and inflammation.

Directions for Use

Swallow the tablet as a whole with a glass of water. Do not crush, chew, or break the tablet. You can take NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL with food to avoid stomach upset. The dose and duration will be decided by your doctor based on your health condition.

Storage

Store in a cool and dry place away from sunlight

Side Effects of NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL

  • Nausea
  • Vomiting
  • Indigestion
  • Stomach pain
  • Headache
  • Heartburn
  • Diarrhoea

In-Depth Precautions and Warning

Drug Warnings

NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may cause liver damage on higher doses or when used for prolonged periods. So, if you notice signs of liver damage such as loss of appetite, nausea, vomiting, unexplained weight loss, dark urine, and fatigue, or if you have abnormal liver function tests, discontinue the treatment immediately and consult your doctor. Do not use other analgesics while using NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL. NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may have affected fertility, so it is not recommended for women trying to conceive. NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may interfere with blood clotting, so it is recommended to stop using this medicine at least 2 weeks before surgery.

Drug Interactions

Drug-Drug Interactions: NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may interact with other nonsteroidal anti-inflammatory drugs or pain killers (ibuprofen, diclofenac, and naproxen, etc.), blood thinners (warfarin and clopidogrel), medicines used to treat nausea and vomiting (metoclopramide and domperidone), an antidepressant (lithium), water pills, anticancer drug (methotrexate), and a medication used to suppress the immune system (cyclosporine), and medicine used to lower cholesterol levels (cholestyramine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL should not be used in patients with liver failure, severe kidney failure, heart failure, gastric ulcers, bleeding disorders, and alcohol or drug abuse.

Drug-Drug Interactions Checker List:

  • IBUPROFEN
  • DICLOFENAC
  • NAPROXEN
  • WARFARIN
  • CLOPIDOGREL
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • LITHIUM
  • METHOTREXATE
  • CYCLOSPORINE
  • CHOLESTYRAMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Consumption of alcohol may increase the risk of liver damage and serious side effects.

    • Safety Warning

      Pregnancy

      unsafe

      NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL is not recommended for use in pregnancy. Please consult your doctor if you are pregnant before taking this medicine.

    • Safety Warning

      Breast Feeding

      unsafe

      NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL should not be used in breastfeeding mothers as it may pass into breastmilk and cause unwanted effects to the nursing baby. However, if prescribed, the doctor may advise you to stop breastfeeding.

    • Safety Warning

      Driving

      safe if prescribed

      NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may not affect your ability to drive. However, do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      unsafe

      NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL should not be used if you have severe liver disease, as this medicine may worsen your condition.

    • Safety Warning

      Kidney

      caution

      NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL should be used with caution if you have kidney problems. your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Children

      unsafe

      NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL is not recommended for use in children below 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.

    • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.

    • In the chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids with a minimum level of chemicals called cytokines, which ramp up inflammation.

    • Your sitting posture is important, especially when have pain and inflammation condition. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

    Patients Concern

    Disease/Condition Glossary

    Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. It can be temporary (acute) or lifelong (chronic). Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone, or organs. At the same time, chronic pain lasts lifelong and can occur due to severe inflammation or tissue damage, such as in cases of osteoarthritis and rheumatoid arthritis. Extreme tissue pain and inflammation caused due to sprains, strains, trauma, or post-surgery may require a prolonged amount of time to heal.

    Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.

    Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.

    FAQs

    How does NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL work?

    NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL contains Nimesulide, Paracetamol, and Serratiopeptidase. Nimesulide and Paracetamol are painkillers and can also reduce fever and inflammation. They act by blocking the action of chemical messengers responsible for pain, fever, and inflammation. Serratiopeptidase is an enzyme that can reduce swelling and promote the healing of damaged tissue. Together, NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL can effectively treat pain, swelling, and inflammation associated with various conditions.

    Does NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL cause liver damage?

    NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL contains Nimesulide and Paracetamol, which may cause liver damage when used in higher doses or longer durations. So, take this medicine for a dose and duration as intended by your doctor. Also, avoid alcohol intake while using this medicine, as alcohol may increase the risk of liver damage.

    Can I stop taking NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL when my pain is relieved?

    In general, NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL is given for short-term pain relief. So, you can stop taking this medicine if your pain subsides. However, it is advised to consult your doctor before stopping this medication.

    What are the side-effects of NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL?

    NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL may cause side effects such as nausea, vomiting, indigestion, stomach pain, headache, heartburn, and diarrhoea. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult a doctor immediately.

    Can I take other painkillers while using NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL?

    You can use other painkillers if prescribed by your doctor. However, ensure other painkillers don't contain nimesulide, paracetamol, and serratiopeptidase to avoid an overdose.

    Available Medicines for

    NIMESULIDE+SERRATIOPEPTIDASE+PARACETAMOL