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Norfloxacin+tinidazole

About Norfloxacin+tinidazole

Norfloxacin+tinidazole is primarily used to treat diarrhoea, dysentery, and stomach infections.  Dysentery is an intestinal infection generally lasting for three to seven days, causing severe diarrhoea with blood. Diarrhoea is a condition characterised by frequent bowel movements, resulting in loose, watery stools.

Norfloxacin+tinidazole is a combination of norfloxacin and tinidazole. Norfloxacin helps by preventing the bacterial cells from dividing and, hence, killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA.

Some side effects of Norfloxacin+tinidazole include nausea, dryness of mouth, stomach upset, and headache.  Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Norfloxacin+tinidazole if you are allergic to Norfloxacin+tinidazole, tinidazole, norfloxacin, or any of its ingredients, as it can lead to abnormal neurological signs (such as dizziness, vertigo, and difficulty in controlling movements).  Norfloxacin+tinidazole should not be taken if you are pregnant or breastfeeding. Diarrhoea can cause dehydration, so please increase your fluid intake. If you have constipation or have blood in your stools, do not take Norfloxacin+tinidazole.

Uses of Norfloxacin+tinidazole

Norfloxacin+tinidazole is used in the treatment of diarrhoea, dysentry, stomach infections. The detailed uses of Norfloxacin+tinidazole are as follows:
• Treatment of Urinary Tract Infections (UTIs): Norfloxacin+tinidazole is commonly prescribed for managing urinary tract infections. It helps relieve symptoms such as frequent urination, a burning sensation during urination, and lower abdominal pain.
• Management of Diarrhea and Dysentery: Norfloxacin+tinidazole is effective against bacterial diarrhea and dysentery, alleviating gastrointestinal discomfort caused by bacterial infections.
• Gastrointestinal Infections: Norfloxacin+tinidazole is useful in treating gastrointestinal conditions like traveler's diarrhea by targeting bacteria responsible for these infections.
• Prevention of Infections in Immunocompromised Individuals: Norfloxacin+tinidazole may also be used as a preventive measure against infections in people with weakened immune systems, such as patients undergoing chemotherapy or those with HIV.
• Respiratory Tract Infections: In certain cases, Norfloxacin+tinidazole is effective in treating both upper and lower respiratory tract infections caused by susceptible bacterial strains.

Medicinal Benefits

  • Norfloxacin+tinidazole is primarily used to treat dysentery, diarrhoea, and upset stomach.
  • Additionally, when Norfloxacin+tinidazole is taken as a course, as directed by a doctor, it helps eradicate and prevent the return of infections caused by microorganisms responsible for digestive tract infections.
  • Norfloxacin+tinidazole plays a vital role in treating diarrhoea and dysentery.
  • Norfloxacin helps by preventing the bacterial cells from dividing and, hence, killing the bacteria.
  • Tinidazole kills parasites that cause infections by damaging their DNA.
  • Both of them help effectively treat the infection by killing the bacteria as they are bactericidal in nature.

Directions for Use

  • Norfloxacin+tinidazole can be taken with or without food, as advised by your doctor. However, avoid taking Norfloxacin+tinidazole with milk or dairy products, as they may reduce its absorption.
  • It is recommended to take Norfloxacin+tinidazole twice daily or as advised by your doctor.
  • Swallow Norfloxacin+tinidazole as a whole with a glass of water.
  • Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Norfloxacin+tinidazole

  • Nausea
  • Dryness of mouth
  • Stomach upset
  • Nausea
  • Headache
  • Metallic taste or change in taste
  • Loss of appetite, weakness
  • Skin rash or itching

Drug Warnings

  • Do not take Norfloxacin+tinidazole if you are allergic to Norfloxacin+tinidazole, tinidazole, norfloxacin, or any of its ingredients.
  • Inform your doctor if you have any kidney or liver problems or any neurologic problems.
  • Norfloxacin, present in Norfloxacin+tinidazole, is known to cause tendon rupture; therefore, be cautious when taking Norfloxacin+tinidazole.
  • In patients having myasthenia gravis (muscle weakness), Norfloxacin+tinidazole should not be taken, as it is known to worsen your condition further.
  • Norfloxacin+tinidazole should not be taken if you are pregnant or breastfeeding. 
  • Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors.
  • Do not start using a new medication without telling your doctor.
  • Diarrhoea can cause dehydration, so please increase the intake of fluids.
  • If you have constipation or have blood in stools, do not take Norfloxacin+tinidazole.
  • Consumption of alcohol, along with Norfloxacin+tinidazole, can cause stomach irritation and increased drowsiness.

Drug Interactions

Drug-Drug Interaction: Norfloxacin+tinidazole may have interaction with pain killers (aspirin, ibuprofen), anti-coagulant/blood thinner (warfarin), anti-gout (probenecid), antibiotics (azithromycin, sulfamethoxazole, ciprofloxacin, trimethoprim, amoxicillin, metronidazole, nitrofurantoin, erythromycin), calcium supplements (calcium/vitamin D), antidiabetics (Glyburide), antiepileptics (Phenobarbital, Phenytoin) and live vaccines (cholera, typhoid).

Drug-Food Interaction: Norfloxacin+tinidazole is known to interact with multivitamins, caffeine, dairy products, and multi-minerals.

Drug-Disease Interaction: Norfloxacin+tinidazole is known to interact if taken along with colitis (inflammation of the colon), CNS disorders, myasthenia gravis (muscle weakness), kidney or liver problems, peripheral neuropathy (nerve damage of the brain), QT interval prolongation, history of tendon rupture, neurological disorders, blood dyscrasia (abnormal disease of blood).

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • IBUPROFEN
  • WARFARIN
  • PROBENECID
  • AZITHROMYCIN
  • CIPROFLOXACIN
  • TRIMETHOPRIM
  • AMOXICILLIN
  • METRONIDAZOLE
  • NITROFURANTOIN
  • ERYTHROMYCIN
  • CALCIUM
  • CHOLERA VACCINE
  • TYPHOID VACCINE
  • SULFAMETHOXAZOLE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Norfloxacin+tinidazole should not be taken along with alcohol as it is known to cause stomach irritation.

    • Safety Warning

      Pregnancy

      consult your doctor

      Caution should be exercised, it is advisable to consult a doctor before using it.

    • Safety Warning

      Breast Feeding

      consult your doctor

      Norfloxacin+tinidazole does not pass on to the child significantly via breast milk, it is advisable to consult a doctor before using it.

    • Safety Warning

      Driving

      caution

      Norfloxacin+tinidazole may cause dizziness and vision problems. So, drive only if you are alert.

    • Safety Warning

      Liver

      caution

      Norfloxacin+tinidazole to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Kidney

      caution

      Norfloxacin+tinidazole to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

    • Safety Warning

      Children

      unsafe

      Norfloxacin+tinidazole is not recommended for children below 12 years of age without a doctor's consent. For children above 12 years, the dose to be adjusted and recommended by a child specialist only.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Antibiotics can alter the useful bacteria in the stomach, which helps indigestion. Therefore, you are advised to take foods rich in probiotics, such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
    • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
    • Avoid foods rich in calcium, such as grapefruit and grapefruit juice, as they might hinder antibiotic absorption.
    • Avoid consumption of alcohol to treat your condition effectively.
    • Avoid the usage of tobacco.
    • To cure your condition effectually, complete the full course of Norfloxacin+tinidazole even though you find symptomatic relief.

    Special Advise

    • Diarrhea can cause dehydration, so please increase the intake of fluids.
    • Norfloxacin present in Norfloxacin+tinidazole is known to cause tendon rupture, so be cautious while taking Norfloxacin+tinidazole if you have a tendon rupture history.
    • Norfloxacin present in Norfloxacin+tinidazole may cause live bacterial vaccines (such as the typhoid vaccine) not to work either. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.
    • You must avoid being in the sunlight for too long as Norfloxacin+tinidazole may make you more sensitive to the sun.

    Patients Concern

    Disease/Condition Glossary

    Dysentery: Dysentery is mostly caused by bacterial intestinal infection by the bacteria Shigella, in which there is inflammation in the intestine, particularly the colon. It generally lasts for three to seven days, causing severe diarrhoea with blood.

    Diarrhoea: It is a condition in which bowel movements are too frequent, leading to loose, watery stools. Acute diarrhoea is a common problem and generally lasts for one or two days, whereas chronic diarrhoea lasts four weeks.

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod-shaped, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

    FAQs

    Norfloxacin+tinidazole is used to treat diarrhoea, dysentery‚ and stomach infections.

    Norfloxacin+tinidazole is a combination of two antibiotics, Norfloxacin, and Tinidazole,‚ primarily taken to treat diarrhoea, dysentery, and severe stomach infections. Norfloxacin helps by preventing the bacterial cells from dividing, thereby killing the bacteria. Tinidazole kills parasites that cause infections by damaging their DNA. Both of them effectively treat the infection by killing the bacteria, as they are bactericidal in nature.

    Yes, Norfloxacin+tinidazole may cause minor skin rashes or reactions. If you are experiencing skin rashes or any allergic reactions, consult a doctor and stop taking Norfloxacin+tinidazole.

    No, Norfloxacin+tinidazole is a combination of two antibiotic drugs that help resolve moderate to severe infections of the stomach. This medicine is not a painkiller. However, completing a full course of Norfloxacin+tinidazole may bring relief to discomfort and stomach pain caused by infections.

    The use of Norfloxacin+tinidazole is considered to be harmful to patients with known allergy to norfloxacin or tinidazole, or any other excipient present in the medicine. It should preferably be avoided in patients with a history of tendinitis (inflammation of the tendons) or tendon rupture. It is also avoided in patients with some neurological disorders.

    Available Medicines for

    Norfloxacin+tinidazole

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