Nimesulide+paracetamol
About Nimesulide+paracetamol
Nimesulide+paracetamol is primarily used to relieve pain in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain.
Nimesulide+paracetamol is composed of Nimesulide and Paracetamol, which work by blocking the effect of prostaglandins, a chemical responsible for inducing pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating).
The most common side effects of Nimesulide+paracetamol include loss of appetite (in cases of liver condition), nausea, vomiting, abdominal pain, persistent tiredness, and dark/discoloured urine. It is not necessary for everyone to experience the side effects above. If you experience any discomfort, speak with your doctor.
Do not take Nimesulide+paracetamol if you are allergic to painkillers such as aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children, people with liver disease, heart disease or gastric ulcers/bleeding problems. Consult your doctor if your pain, inflammation, and fever symptoms do not improve even after 10 days.
Uses of Nimesulide+paracetamol
• Pain Relief: Nimesulide+paracetamol relieves mild to moderate pain, such as headaches, muscle aches, and joint pain.
• Fever Reduction: Nimesulide+paracetamol helps to reduce fever, relieving discomfort caused by high body temperature.
• Arthritis Management: Nimesulide+paracetamol is involved in managing arthritis symptoms by reducing pain and inflammation.
• Post-operative Care: Nimesulide+paracetamol helps to manage post-operative pain, making recovery more comfortable after surgery.
• Chronic Pain Conditions: Nimesulide+paracetamol provides relief for chronic pain conditions, helping when other treatments may not be enough.
• Respiratory Infection Relief: Nimesulide+paracetamol is also used to alleviate pain, fever, and inflammation associated with respiratory infection.
Medicinal Benefits
- Provides effective relief from mild to moderate pain.
- Reduces fever quickly.
- Helps decrease inflammation and swelling.
- Useful for conditions such as headaches, toothaches, and muscle pain.
- Relieves joint pain and stiffness.
- Helps ease menstrual pain (period cramps).
- Improves comfort in fever associated with infections.
Directions for Use
- Nimesulide+paracetamol should be taken with food.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Nimesulide+paracetamol as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Nimesulide+paracetamol
- Nausea
- Vomiting
- Loss of appetite
- Abdominal pain
- Persistent tiredness
- Dark/discoloured urine
Medicines Containing this Salt
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Drug Warnings
- Nimesulide+paracetamol is contraindicated in patients with a history of hypersensitivity (allergic) reaction to Nimesulide+paracetamol, paracetamol, nimesulide, or other pain killers.
- Please inform your doctor before starting Nimesulide+paracetamol if you have an active stomach ulcer, recent gastrointestinal bleeding, asthma, recent heart bypass surgery or severe kidney/liver impairment.
- Nimesulide present in Nimesulide+paracetamol is known to affect fertility, so if you are planning for pregnancy, contact the doctor. Nimesulide+paracetamol should be avoided in both pregnant women (especially in the last trimester of pregnancy) and breastfeeding women, as it may pass through the milk, affecting the baby.
- Patients with heart diseases and recent stroke (bleeding in the brain) should not take Nimesulide+paracetamol as a substitute for aspirin.
- It should not be given to children (below 12 years) with symptoms of fever and chills or suffering from influenza (flu) or chickenpox.
- Inform your doctor about any bleeding disorders as nimesulide in Nimesulide+paracetamol should be taken with care as it may interfere with the functioning of platelets.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking any of these medicines, as there may be an interaction.
- High blood pressure-lowering medicines (Amlodipine)
• Potential effect: May increase the risk of kidney problems. - Diuretic/water pills (hydrochlorothiazide, furosemide)
• Potential effect: May increase the risk of kidney problems. - Blood thinners (warfarin)
• Potential effect: May increase the risk of bleeding disorders. - Pain killers (Ibuprofen, Aspirin)
• Potential effect: May cause side effects like bleeding or stomach irritation.
Drug-Food Interactions:
- Excessive intake of alcoholic beverages, caffeine-containing food or drinks like coffee, tea, chocolate, and some fizzy drinks should be avoided while taking Nimesulide+paracetamol. Taking together may lead to drowsiness, dizziness, and sleepiness.
Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Nimesulide+paracetamol, as it may worsen your condition or cause complications.
- Bleeding disorders, like haemophilia, von Willebrand disease, or low blood platelets
- Children suffering from influenza (flu) or chickenpox
- Gastric or duodenal ulcers.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeTaking Nimesulide+paracetamol with alcohol may cause dizziness or drowsiness. Besides this, it can also damage your liver if taken for a longer duration. So, avoid or limit the intake of alcoholic beverages with Nimesulide+paracetamol.
Pregnancy
unsafeUse of Nimesulide+paracetamol during pregnancy is not recommended as taking this medicine during the last 3 months of pregnancy may harm the unborn baby. Consult your doctor for further advice.
Breast Feeding
unsafeUse of Nimesulide+paracetamol during breastfeeding is not recommended as it may pass through the milk and harm the baby. Consult your doctor for further advice.
Driving
unsafeAfter taking Nimesulide+paracetamol, you may notice dizziness, sleepiness, drowsiness. So, you should stop taking Nimesulide+paracetamol and contact your doctor.
Liver
cautionNimesulide+paracetamol to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.
Kidney
cautionNimesulide+paracetamol to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.
Children
unsafeNimesulide+paracetamol is contraindicated in children below 20 kg body weight or younger than 6 years of age. It may cause kidney problems in children and adolescents who are dehydrated.
Habit Forming
Diet & Lifestyle Advise
Diet
- Eat light, balanced meals with fruits and vegetables to support recovery
- Stay well hydrated by drinking plenty of water
- Avoid alcohol, as it can increase the risk of liver damage
Lifestyle changes
- Get adequate rest to help the body recover from pain or fever
- Use proper posture and avoid strain during daily activities to prevent worsening pain
Physical activity
- Prefer light activities like walking or gentle stretching to avoid worsening pain
- Avoid heavy exercise or strenuous work until the pain and inflammation reduce
- Gradually return to normal physical activity as symptoms improve
Patients Concern
Disease/Condition Glossary
Pain: Pain can be short-term (acute) or long-term (chronic) in nature. Acute pain is, for a short time, caused by damage to the tissues of the muscle, bone or organs. At the same time, chronic pain lasts longer; it is caused by pathologies such as nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. Many women have painful periods known as dysmenorrhea, most often menstrual cramps. On the other hand, osteoarthritis is a degenerative disease that causes chronic joint pain (especially in the knee) and stiffness, making daily tasks difficult.
FAQs
Nimesulide+paracetamol is used to relieve pain in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and dysmenorrhea. Besides this, it is also useful for dental pain, muscle pain, back pain, ear pain, and throat pain.
Nimesulide+paracetamol works by blocking the effects of prostaglandins, chemicals that induce pain and inflammation in the body. It also lowers the elevated body temperature by promoting heat loss (through sweating), which helps reset the hypothalamic thermostat. Together, Nimesulide+paracetamol helps relieve pain.
No, Nimesulide+paracetamol is not indicated for stomach pain. If you have stomach pain post-ingestion, it may be a sign of a stomach ulcer or gastric bleeding. Do not take Nimesulide+paracetamol in this condition. It is better to inform your doctor if you experience stomach pain after ingesting this medication.
No, Nimesulide+paracetamol should not be taken as a long-term medication as it may lead to stomach ulcers/bleeding and kidney problems. For best results, take it at the doses and for the duration advised by your doctor.
Yes, Nimesulide+paracetamol should preferably be taken with food to avoid an upset stomach. If taken on an empty stomach, it may cause stomach irritation and upset.
You should not take Nimesulide+paracetamol if you have a history of peptic ulceration, a history of gastrointestinal haemorrhage, Crohn's disease or ulcerative colitis.
No, Nimesulide+paracetamol should not be taken if you plan to get pregnant, as it contains nimesulide, which may cause birth defects. So, before starting Nimesulide+paracetamol, please consult your doctor if you are pregnant or planning a pregnancy.
Though Nimesulide+paracetamol may be used for tooth pain, it should not be used in children unless advised by the doctor. Please consult the doctor before using Nimesulide+paracetamol in children; the doctor will prescribe appropriate medicine based on the child’s condition.
Nimesulide+paracetamol is a combination medication that belongs to the class of painkillers called non-steroidal anti-inflammatory drugs. It is mainly prescribed to treat pain and relieve discomfort caused by tooth pain, arthritis, period pain, and other types of short-term pain.
As Nimesulide+paracetamol is indicated for short-term pain relief, it can be discontinued once pain relief is achieved. However, it is advised to take Nimesulide+paracetamol for the prescribed duration to effectively treat your condition.
Taking Nimesulide+paracetamol may cause nausea and vomiting. If you feel sick, talk to your doctor or pharmacist for help. To cope with nausea and vomiting, take your medicine with food or milk, eat small meals, and stay hydrated. Avoid spicy foods and lying down after taking the medicine. Try ginger products like ginger tea or candies. If your symptoms are severe, ask your doctor for help.
Don't take Nimesulide+paracetamol if you're allergic to it or other painkillers, have stomach ulcers or bleeding, asthma, recent heart surgery, severe kidney or liver problems. Consult the doctor if you are pregnant or breastfeeding.
Nimesulide+paracetamol can be taken with vitamin B-complex if prescribed by your doctor. Please consult your doctor if you have any concerns.
Nimesulide+paracetamol may cause harm to the liver, especially if used for a longer duration or in higher doses. So, do not take a higher dose than the recommended dose of Nimesulide+paracetamol.
Taking more than the recommended dose of Nimesulide+paracetamol is dangerous. Overuse of Nimesulide+paracetamol can harm your liver and kidneys, which can be life-threatening. Always follow the dosage instructions as advised by the doctor.
Nimesulide+paracetamol should be stored in a cool, dry place away from sunlight. Keep away from children and pets.
Though Nimesulide+paracetamol may help lower body temperature, it is primarily used for pain relief. Consult your doctor before taking Nimesulide+paracetamol for fever or if you have any concerns.
Follow your doctor's advice and take the right amount of medicine. Inform your doctor about any health problems, allergies, or other drugs you're taking. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.
You are recommended to consult your doctor before taking other medications while using Nimesulide+paracetamol to avoid drug interactions.
If you suspect an overdose of Nimesulide+paracetamol, seek medical help immediately. Quick action can help prevent serious harm, so don’t wait to seek medical attention.
The common side effects of Nimesulide+paracetamol include loss of appetite, nausea, vomiting, abdominal pain, persistent tiredness, or dark or discoloured urine. Not everyone experiences the side effects above. If you experience any discomfort, speak with your doctor.
