OFLOXACIN+SATRANIDAZOLE belongs to the class of ‘antibiotics’, primarily used to treat diarrhoea and dysentery. It helps treat bacterial infections, including intra-abdominal infection, gynaecological and pelvic infections, foot ulcers in diabetes, post-operative infections, dental infections, and infections in immunocompromised patients. Diarrhoea is a condition that causes the frequent passing of loose or watery stools. Dysentery is an intestinal inflammation that leads to severe diarrhoea accompanied by mucus or blood in the stools. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body.
OFLOXACIN+SATRANIDAZOLE contains two antibiotic medicines, namely: Ofloxacin and Satranidazole. Ofloxacin belongs to a class of drugs called quinolone antibiotics. It works by inhibiting bacterial DNA gyrase, an enzyme required to replicate, transcription, and repair the DNA. Satranidazole is an anti-amoebic, antiprotozoal, and anti-bacterial medicine that treats various infections caused by bacteria and parasites (amoeba). It is bactericidal and kills harmful bacteria and parasites (amoeba) by damaging its DNA. It prevents the division of bacterial cells and inhibits the repairing of bacterial cells.
Please take OFLOXACIN+SATRANIDAZOLE in the dose and duration prescribed by your doctor based on your medical condition. OFLOXACIN+SATRANIDAZOLE is generally safe to use. However, some may experience side effects like nausea, vomiting, stomach pain, loss of appetite, dizziness, and headache. Most of these side effects of OFLOXACIN+SATRANIDAZOLE do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.
If you are allergic to OFLOXACIN+SATRANIDAZOLE or any other medicines, please tell your doctor. Do not suddenly stop this medicine to avoid unpleasant side effects and sudden withdrawal symptoms. Intake of probiotics, prebiotics, and plenty of fluids is recommended if you suffer from dysentery and diarrhoea. Do not drive or operate heavy machinery after taking OFLOXACIN+SATRANIDAZOLE as it may cause dizziness. Please try avoiding alcoholic beverages during your treatment as it can cause flushing and a general sick feeling. Pregnant and breastfeeding women should use OFLOXACIN+SATRANIDAZOLE with proper consultation and caution.
Bacterial infections, dysentery, and diarrhoea.
OFLOXACIN+SATRANIDAZOLE contains two antibiotic medicines, namely: Ofloxacin and Satranidazole. Ofloxacin is a quinolone antibiotic that inhibits bacterial DNA gyrase, an enzyme required for replicating, transcription, and repairing the DNA. Satranidazole is an anti-amoebic, antiprotozoal, and anti-bacterial medicine effective against a wide range of gram-positive and gram-negative bacteria. It kills the harmful anaerobic bacteria and certain anaerobic protozoa (Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia) causing diarrhoea. It is bactericidal and kills harmful bacteria and parasites (amoeba) by damaging its DNA. It also prevents the division of bacterial cells and inhibits the repairing of bacterial cells.
Brief your medical history to the doctor if you are allergic to OFLOXACIN+SATRANIDAZOLE or any of its components. Please let your doctor know in advance if you have liver or kidney diseases, tendonitis, fits, blood dyscrasia, colitis, diabetes, myasthenia gravis (muscle weakness), dehydration, high blood pressure, nerve problems (peripheral neuropathy), mental/mood disorders (depression) or undergoing dialysis treatment. Please consult your doctor if you are planning to become pregnant or already pregnant before starting OFLOXACIN+SATRANIDAZOLE. Do not drive or operate heavy machinery after taking OFLOXACIN+SATRANIDAZOLE as it may cause dizziness and visual disturbances. Please try avoiding alcoholic beverages during your treatment as it can cause flushing and a general sick feeling. OFLOXACIN+SATRANIDAZOLE is not recommended for children less than 18 years of age.
Drug-Drug Interaction: OFLOXACIN+SATRANIDAZOLE may interact with blood thinners (acenocoumarol, warfarin), pain killers (aspirin), herbal products (ginkgo), respiratory drugs (albuterol), and medicines used to treat alcohol addiction (disulfiram).
Drug-Food Interaction: The consumption of alcoholic beverages should be avoided as it may lead to flushing, drowsiness, and dizziness.
Drug-Disease Interaction: Inform your doctor before starting OFLOXACIN+SATRANIDAZOLE if you have liver or kidney diseases, tendonitis, fits, blood dyscrasia, colitis, diabetes, myasthenia gravis, dehydration, dialysis, high blood pressure, nerve problems, and mental/mood disorders (depression).
Alcohol consumption may worsen the side effects of OFLOXACIN+SATRANIDAZOLE like dizziness and visual disturbances. It is better to avoid alcohol while you are being treated with OFLOXACIN+SATRANIDAZOLE.
There is limited data on how the OFLOXACIN+SATRANIDAZOLE affects pregnancy. Please consult your doctor if you are planning to become pregnant or already pregnant before starting OFLOXACIN+SATRANIDAZOLE.
OFLOXACIN+SATRANIDAZOLE is excreted into the breast milk and may affect the nursing infants. Please consult your doctor before taking OFLOXACIN+SATRANIDAZOLE if you are breastfeeding.
Do not drive or operate machinery if you experience any impairment of skills, dizziness and visual disturbances while using OFLOXACIN+SATRANIDAZOLE.
Please take OFLOXACIN+SATRANIDAZOLE with caution and doctor’s advice if you have a history of liver diseases/conditions.
Please take OFLOXACIN+SATRANIDAZOLE with caution and doctor’s advice if you have a history of kidney diseases/conditions.
OFLOXACIN+SATRANIDAZOLE is not recommended for children less than 18 years of age.
Diarrhoea is a condition that causes the frequent passing of loose or watery stools. It is caused by bacteria (campylobacter and Escherichia coli), virus (norovirus or rotavirus), and parasites in contaminated food and water.
Dysentery is an intestinal inflammation that leads to severe diarrhoea accompanied by mucus or blood in the stools. It is mostly caused by shigella bacteria (shigellosis) or an amoeba.
Bacterial infection occurs when harmful bacteria grow in the body and causes infection. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes, spherical, rod and spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever, and tiredness.