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Olmesartan+cilnidipine+chlorthalidone

About Olmesartan+cilnidipine+chlorthalidone

Olmesartan+cilnidipine+chlorthalidone belongs to the class of medicines called hypertensives, primarily used to treat hypertension (high blood pressure). Hypertension or high blood pressure is a chronic condition in which the force of blood against the artery wall is high.

Olmesartan+cilnidipine+chlorthalidone contains Olmesartan, Cilnidipine, and Chlorthalidone, which work by relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.

Take Olmesartan+cilnidipine+chlorthalidone as advised by the doctor. You may experience side effects like headache, nausea, swelling of legs/hands, or dizziness. Most of the side effects of Olmesartan+cilnidipine+chlorthalidone do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Olmesartan+cilnidipine+chlorthalidone if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent any interactions.

Uses of Olmesartan+cilnidipine+chlorthalidone

Olmesartan+cilnidipine+chlorthalidone used in the treatment of Hypertension. The detailed uses of Olmesartan+cilnidipine+chlorthalidone are as follows: • Management of high blood pressure: Olmesartan+cilnidipine+chlorthalidone helps to lower blood pressure by relaxing blood vessels and reducing fluid retention. • Reducing cardiovascular risk: Olmesartan+cilnidipine+chlorthalidone reduces the risk of heart attacks, strokes, and kidney problems associated with high blood pressure.

Medicinal Benefits

  • Helps effectively lower high blood pressure by combining three complementary medicines.
  • Relaxes and widens blood vessels, allowing smoother blood flow and easier heart function.
  • Reduces the workload on the heart, improving overall cardiac efficiency.
  • Removes excess fluid and salts from the body, helping maintain healthy blood pressure levels.
  • Lowers the risk of serious complications such as heart attack and stroke.
  • Provides cardiovascular protection by reducing strain on the heart and blood vessels.
  • Helps protect the kidneys from damage caused by long-term high blood pressure.
  • Supports long-term blood pressure control and overall heart-kidney health.

Directions for Use

  • Olmesartan+cilnidipine+chlorthalidone can preferably be taken with food to avoid stomach upset, or as prescribed by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Olmesartan+cilnidipine+chlorthalidone as a whole with a glass of water.
  • Do not chew, crush, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Olmesartan+cilnidipine+chlorthalidone

  • Dizziness
  • Low blood pressure
  • Flushing
  • Headache
  • Palpitations (pounding heartbeat)
  • Frequency of urination
  • Lethargy (feeling weak)

Drug Warnings

  • Olmesartan+cilnidipine+chlorthalidone should not be given to people who are allergic to any of its components, or have low blood pressure (less than 90 mm of Hg).
  • Inform your doctor if you have had a heart attack, kidney disease, liver disease, are pregnant, planning to get pregnant, or breastfeeding.
  • Grapefruit juice and St. John's wort plant should not be consumed when taking Olmesartan+cilnidipine+chlorthalidone as it is contraindicated.
  • Let your doctor know if you are taking any other medicines.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking any of these medicines, as there may be an interaction.

  • High blood pressure-lowering medicines (Benazepril, Aliskiren)
    Potential effect: May increase the risk of side effects like low blood pressure and kidney problems.
  • Anti-manic agent (Lithium)
    • Potential effect: May increase the effects of lithium, leading to unpleasant effects.
  • Anti-epilepsy medicines (Carbamazepine)
    Potential effect: May increase the risk of low salt levels in the blood.
  • Medicines used to prevent organ rejection (Cyclosporine, Tacrolimus)
    Potential effect: May cause kidney damage and high potassium levels.
  • Painkillers (Ibuprofen, Aspirin)
    • Potential effect: May reduce the effect of Olmesartan+cilnidipine+chlorthalidone in lowering blood pressure.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Inform your doctor if you have any of these conditions.

  • Heart problems
  • Low blood pressure
  • Liver disease
  • Kidney problem

Drug-Drug Interactions Checker List:

  • BENAZEPRIL
  • ALISKIREN
  • LITHIUM
  • CARBAMAZEPINE
  • CYCLOSPORIN
  • TACROLIMUS
  • IBUPROFEN
  • ASPIRIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Alcohol should not be taken while using Olmesartan+cilnidipine+chlorthalidone. It may worsen the health condition by increasing the risk of side effects.

    • Safety Warning

      Pregnancy

      unsafe

      Olmesartan+cilnidipine+chlorthalidone is a category C medicine and may cause harmful effects to the fetus or unborn baby. So, it is not recommended for use in pregnant women.

    • Safety Warning

      Breast Feeding

      consult your doctor

      Olmesartan+cilnidipine+chlorthalidone should be used with caution in breastfeeding mothers. Please consult your doctor before use.

    • Safety Warning

      Driving

      caution

      Olmesartan+cilnidipine+chlorthalidone may cause dizziness and affect your ability to drive. So, do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      caution

      Olmesartan+cilnidipine+chlorthalidone should be used with caution in patients with liver diseases. The dose may have to be adjusted by the doctor as required.

    • Safety Warning

      Kidney

      caution

      Olmesartan+cilnidipine+chlorthalidone should be used with extreme caution in patients with kidney diseases. The dose may have to be adjusted by the doctor as required.

    • Safety Warning

      Children

      unsafe

      Olmesartan+cilnidipine+chlorthalidone is not recommended for use in children below 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    Healthy Weight Management:

    • Keep your weight under control by maintaining a BMI between 19.5 and 24.9.
    • Achieving a healthy weight helps reduce strain on the heart and blood vessels.

    Physical Activity:

    • Engage in regular physical activity for at least 150 minutes per week.
    • Aim for about 30 minutes of exercise on most days to help lower blood pressure.
    • Regular exercise can reduce raised blood pressure by around 5 mm Hg.

    Healthy Diet:

    • Choose a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
    • Include balanced meals that support heart health and blood pressure control.

    Salt Intake:

    • Control Limit sodium (table salt) intake to no more than 2300 mg per day.
    • Reducing sodium to below 1500 mg per day is ideal for most adults.

    Stress Management:

    • Avoid chronic stress, as it can increase blood pressure levels.
    • Spend quality time with loved ones to promote emotional well-being.
    • Practice mindfulness techniques to help manage daily stress.

    Special Advise

    • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: It is a chronic (long-term) condition in which blood pressure is elevated persistently at higher than normal levels. It occurs when the blood’s force against the wall of blood vessels is too high. This condition can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes damage to the brain, kidneys, and eyes. The risk of high blood pressure complications increases with the following: obesity, smoking, diabetes, alcohol intake, lack of physical inactivity, stress, and kidney diseases.

    FAQs

    Olmesartan+cilnidipine+chlorthalidone is used to treat high blood pressure (hypertension).

    Olmesartan+cilnidipine+chlorthalidone reduces elevated blood pressure. It contains Olmesartan, Cilnidipine, and Chlorthalidone. Olmesartan is an angiotensin-II receptor blocker (ARB). Angiotensin narrows the blood vessels increasing the blood pressure, therefore blocking angiotensin can result in widening of the narrowed blood vessels. Cilnidipine is a calcium channel blocker. It acts by relaxing the blood vessels and improving the blood flow. Chlorthalidone is a diuretic or water pill that acts by expelling excess water and salt from the body. It helps in decreasing fluid accumulation and oedema (fluid overload).

    Olmesartan+cilnidipine+chlorthalidone may cause low blood pressure resulting in dizziness or fainting. It may also cause orthostatic hypotension (sudden drop in blood pressure while standing up), so rise slowly while standing up from a sitting or lying position.

    You should not discontinue using Olmesartan+cilnidipine+chlorthalidone without consulting your doctor. The doctor may monitor your blood pressure for at least two weeks before reducing the dose and gradually stopping the medicine.

    The common side-effects of Olmesartan+cilnidipine+chlorthalidone are dizziness, low blood pressure, flushing (reddening of the skin, especially face), headache, palpitations (pounding heartbeat), increased micturition (frequency of urination), and lethargy (feeling weak). These side-effects are usually mild and resolve without requiring any medical attention. However, if any of these side-effects persist or get worse, inform your doctor immediately.

    Please inform your doctor before surgery if you are taking Olmesartan+cilnidipine+chlorthalidone as it needs to be stopped because it might lower the blood pressure further if taken along with general anaesthesia.

    Both Olmesartan+cilnidipine+chlorthalidone and olmesartan medoxomil are used to treat high blood pressure (hypertension). However, Olmesartan+cilnidipine+chlorthalidone contains three active ingredients: olmesartan medoxomil, cilnidipine, and chlorthalidone, while olmesartan medoxomil contains only one active ingredient.

    Olmesartan+cilnidipine+chlorthalidone can be used with caution in elderly patients. Elderly patients may be more susceptible to hypotensive effects, increasing the risk of falls, dizziness, and orthostatic hypotension. Close monitoring by their healthcare provider is recommended.

    Olmesartan+cilnidipine+chlorthalidone is not recommended for pregnant and breastfeeding women. This combination of medications can harm the fetus or baby, and alternative treatments should be considered. Women of childbearing age should discuss their pregnancy plans with their doctor before starting treatment.

    Olmesartan+cilnidipine+chlorthalidone is not recommended for patients with severe kidney and liver diseases. Patients with mild to moderate kidney or liver disease should use it with caution and under close medical supervision.

    Yes, Olmesartan+cilnidipine+chlorthalidone may cause dizziness in some individuals. To manage dizziness, stay hydrated, get enough rest, and avoid standing for long periods. Also, avoid sudden movements, improve lighting, eat smaller meals, exercise regularly, and manage stress. Consult your doctor if dizziness persists.

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