PRUCALOPRIDE belongs to the group of medicines called gastrointestinal prokinetics used to treat chronic idiopathic constipation. Chronic idiopathic constipation is a functional bowel disorder characterised by difficult or incomplete and/or infrequent passage of stools that lasts for 3months or longer and is not caused by any disease or medication.
PRUCALOPRIDE contains ‘prucalopride’, which acts on the muscle walls of the gut, and increases bowel motility. Thereby, helps restore the normal functioning of the bowel and treats constipation. PRUCALOPRIDE helps treat chronic constipation in adults in whom laxatives do not work well.
You are advised to take PRUCALOPRIDE for as long as your doctor has prescribed it to you. In some cases, you may experience certain common side-effects such as headache, diarrhoea, nausea, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Avoid taking PRUCALOPRIDE if you are pregnant or breastfeeding. PRUCALOPRIDE is not recommended for children below 18 years as safety and effectiveness have not been established. PRUCALOPRIDE may cause dizziness and tiredness, so drive only if you are alert. Keep your doctor informed about your health condition and the medicines you are taking to rule out any unpleasant side effects or interactions.
Chronic idiopathic constipation
PRUCALOPRIDE belongs to the group of medicines called gastrointestinal prokinetics used to treat chronic idiopathic constipation. PRUCALOPRIDE acts on the muscle walls of the gut and increases bowel motility. Thereby, helps restore the normal functioning of the bowel and treats constipation. PRUCALOPRIDE helps treat chronic constipation in adults in whom laxatives do not work well.
Do not take PRUCALOPRIDE if you are allergic to any of its components, if you are on renal dialysis, have perforation/obstruction of the gut wall, inflammation of the intestinal tract, Crohn’s disease, toxic megacolon/megarectum or ulcerative colitis. Inform your doctor if you have AIDS, hormonal problems, neurological disease, suicidal tendency, mood disorder, cancer, heart, kidney or liver problems. Avoid taking PRUCALOPRIDE if you are pregnant or breastfeeding. PRUCALOPRIDE is not recommended for children below 18 years as safety and effectiveness have not been established. PRUCALOPRIDE may cause dizziness and tiredness, so drive only if you are alert.
Drug-Drug Interactions: PRUCALOPRIDE may interact with an antihistamine (diphenhydramine).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have renal dialysis, perforation/obstruction of the gut wall, inflammation of the intestinal tract, Crohn’s disease, toxic megacolon/megarectum, ulcerative colitis, mood disorders, or suicidal tendency.
It is not known if alcohol interacts with PRUCALOPRIDE. Please consult your doctor if you have any concerns regarding this.
PRUCALOPRIDE is not recommended during pregnancy. Use a reliable method of contraception while taking PRUCALOPRIDE. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
PRUCALOPRIDE might pass into breastmilk. Avoid breastfeeding while taking PRUCALOPRIDE.
PRUCALOPRIDE is unlikely to affect your ability to drive. However, sometimes PRUCALOPRIDE might cause dizziness and tiredness, so drive only if you are alert.
Please consult your doctor if you have liver impairment/liver disease.
Please consult your doctor if you have kidney impairment/kidney disease.
PRUCALOPRIDE is not recommended for children below 18 years as safety and effectiveness have not been established.
Chronic idiopathic constipation: Chronic idiopathic constipation is a functional bowel disorder characterised by difficult or incomplete and/or infrequent passage of stools that lasts for 3months or longer and is not caused by any disease or medication. Symptoms include bloating, abdominal pain, and feeling as if the bowel movement is incomplete. Constipation occurs when the normal muscle contractions in the large intestine slow down, which causes the incomplete elimination of the bowel from the body. Constipation could be associated with a sudden change of diet, a diet with less fibre, not drinking enough liquids, lack of exercise, loss of tone of the bowel muscles in older people, or having to stay in bed for a longer duration.