About RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL
RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL belongs to a group of antiretroviral medicines used to treat HIV infection. HIV (Human Immunodeficiency Virus) attacks the immune system and destroys the white blood cells that help fight infections, making the individual susceptible to other infections or illnesses.
RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL is a combination of four drugs: Lamivudine, Atazanavir, Ritonavir and Tenofovir disoproxil. Lamivudine is a nucleoside reverse transcriptase inhibitor, and Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. These two drugs work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the virus's reproduction. Atazanavir and Ritonavir belong to the class of protease inhibitors. They work by inhibiting the protease enzyme production, which HIV-infected cells require to make new viruses. This effect helps to inhibit viral replication. Altogether, RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL helps in treating HIV infection.
Take RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL exactly as prescribed by the doctor. The dose of this medicine will be decided by your doctor, depending on your medical condition. This medicine may cause certain common side effects such as dizziness, nausea, vomiting, diarrhea, weakness, and rash. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.
It is not recommended to take RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL if you are allergic to any contents of it. Practise safe sex and other necessary precautions as RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning pregnancy. Avoid breastfeeding while taking RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL. RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL may cause dizziness, so drive with caution. RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL is not recommended for children as safety is not established. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects. Before taking RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL, inform your doctor if you have liver disease, hepatitis B or C (liver infections), haemophilia (bleeding disorder), erectile dysfunction, diabetes, gall stones, and kidney disease.
Uses of RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL
HIV infection
Medicinal Benefits
RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL belongs to a group of antiretroviral medicines used to treat HIV infection. RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL is a combination of four drugs: Lamivudine, Atazanavir, Ritonavir and Tenofovir disoproxil. Lamivudine is a nucleoside reverse transcriptase inhibitor, and Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. These two drugs work by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the virus's reproduction. Atazanavir and Ritonavir belong to the class of protease inhibitors. They work by inhibiting the protease enzyme production, which HIV-infected cells require to make new viruses. This effect helps to inhibit viral replication. Altogether, RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL helps in treating HIV infection.
Directions for Use
Storage
Side Effects of RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL
- Stomach ache
- Diarrhea
- Nausea and Vomiting
- Flushing (reddening of the skin)
- Headache
- Dizziness
- Upset stomach
- Bad taste in the mouth
- Nerve damage
- Itching
- Rash
- Joint pain and back pain
- Indigestion
- Fatigue (tiredness)
In-Depth Precautions and Warning
Drug Warnings
Do not take RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL if you are allergic to its components. Inform your doctor if you have a history of hepatitis B or C infection, bone problems, pancreas disorder, kidney or liver problems or are older than 65. Practise safe sex and other necessary precautions as RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL does not prevent the spread of HIV infection. Consult your doctor if you are pregnant or planning pregnancy. Avoid breastfeeding while taking RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL. RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL may cause dizziness, so drive with caution. RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL is not recommended for children as safety and efficacy are not established. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation. RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL may lead to opportunistic infections (infections that occur frequently or severely in patients with weak immune systems), so inform your doctor immediately if you experience symptoms of infection such as muscle weakness, weakness beginning in the hands and feet that progress towards the trunk, palpitations (pounding heartbeat), and tremors.
Drug Interactions
Drug-Drug Interactions: RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL may interact with anti-HIV (ritonavir, darunavir), anti-fungal (amphotericin B), anti-viral (foscarnet, ganciclovir), antimicrobial (pentamidine), antibiotic (vancomycin), anti-cancer (interleukin-2), immunosuppressant (tacrolimus). Anti-allergy medicines (astemizole and terfenadine), medicines used to correct heartbeats (amiodarone, bepridil), a medicine used to treat migraine (dihydroergotamine and ergotamine), antipsychotic drugs (clozapine, quetiapine), antidepressants (lurasidone and Hypericum perforatum), a medicine used to treat stomach problems (cisapride), medicines used to treat erectile dysfunction (sildenafil, tadalafil), a medicine used to treat gout (colchicine), anticoagulant (warfarin), medicines used to lower blood, medicines used to treat heart disease (digoxin), oral contraceptives (ethinyl estradiol).
Drug-Food Interactions: Avoid alcohol consumption.
Drug-Disease Interactions: Inform your doctor if you have hepatitis B, pancreatitis, bone problems, or kidney or liver problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionConsumption of alcohol may increase the risk of side effects. Hence, avoid consumption of alcohol while on treatment with RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL.
Pregnancy
cautionRITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL has the potential to damage the foetus. Before using this medicine, tell your doctor if you are pregnant or intend to become pregnant. It will only be prescribed to you if it is clearly required. If you become pregnant while using RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL, your doctor will do additional checks (including blood tests) to ensure your baby is developing normally.
Breast Feeding
cautionSmall amounts of this medicine pass into breast milk. Hence, RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL should be used with caution in nursing mothers. Your doctor may suggest you to stop breastfeeding while on treatment with this medicine.
Driving
cautionRITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Liver
cautionRITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL should be used with caution in patients with liver diseases. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
cautionRITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL should be used with caution in patients with kidney diseases. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
unsafeRITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL is not recommended for children as safety and efficacy are not established.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
- Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
- Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
- Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
- Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
- Avoid sharing used needles, other injection or drug equipment.
- Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
- Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
- Drink more fluids and avoid alcoholic beverages to prevent dehydration.
Special Advise
- Get an HIV test done for at least every three months.
- Regular kidney and liver function and bone mineral density tests while taking RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL are advised.
- RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL might affect laboratory test results; inform the person doing the tests that you are taking RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL.
- Regularly get blood and urine tests done while taking RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL.
- RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking RITONAVIR+ATAZANAVIR+LAMIVUDINE+TENOFOVIR DISOPROXIL should be carefully monitored throughout the treatment.
Patients Concern
Disease/Condition Glossary
HIV infection: HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by using antiretroviral agents.