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About SERTRALINE+ALPRAZOLAM

SERTRALINE+ALPRAZOLAM belongs to the class of medications called ‘antidepressant’ used in the treatment of panic disorder with or without agoraphobia (fear of leaving one’s own home or being in open or crowded places).  Panic disorder is characterized by a panic attack in which the patient experiences a sudden feeling of terror even if there is no real danger.

SERTRALINE+ALPRAZOLAM contains Alprazolam and Sertraline. Alprazolam is a benzodiazepine. It works by increasing the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby, SERTRALINE+ALPRAZOLAM relaxes muscles, produces a calming effect, and helps to fall asleep. Sertraline is a selective serotonin reuptake inhibitor (SSRI). It increases the release of the serotonin hormone in the body, which is responsible for improving mood, cognition, and memory.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of SERTRALINE+ALPRAZOLAM are nausea (feeling sick), increased appetite, restlessness, drowsiness, dizziness, headache, constipation, dry mouth, jerks or uncoordinated movements, numbing or tingling sensation, vision problems, tinnitus (ringing in ears), ejaculation failure, and fatigue (extreme tiredness). Inform your doctor immediately if any of these side-effects persist or get worse.

It is not recommended to take SERTRALINE+ALPRAZOLAM if you are allergic to any of its contents. Do not use SERTRALINE+ALPRAZOLAM in patients with severe liver problems, severe breathing problems, myasthenia gravis (a muscle disorder), and if you have been taking monoamine oxidase inhibitors (MAOI) within 2 weeks. It is not recommended for use in children, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people as dose adjustments are necessary. Do not consume alcohol as it may cause excessive drowsiness. SERTRALINE+ALPRAZOLAM may cause drowsiness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of SERTRALINE+ALPRAZOLAM

Panic disorder.

Medicinal Benefits

SERTRALINE+ALPRAZOLAM is used to treat panic disorder. It can restore the chemicals in the brain that can produce a calming effect and improve mood, energy and behavior. It also improves the overall well-being and quality-of-life of the patient. It can also help to sleep better. You should take this medicine as intended by the doctor for effective results.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of SERTRALINE+ALPRAZOLAM

  • Nausea (feeling sick)
  • Increased appetite
  • Restlessness
  • Drowsiness
  • Dizziness
  • Headache
  • Constipation
  • Dry mouth
  • Jerks or uncoordinated movements
  • Numbing or tingling sensation
  • Vision problems
  • Tinnitus (ringing in ears)
  • Ejaculation failure
  • Fatigue (extreme tiredness)

In-Depth Precautions and Warning

Drug Warnings

It is not recommended to use SERTRALINE+ALPRAZOLAM concomitantly with monoamine oxidase inhibitors (MAOI), medicines used to treat mental illness, and opioid pain killers as it may cause serious side-effects. Before taking SERTRALINE+ALPRAZOLAM, inform your doctor if you have mental illness, liver, lungs, or kidney problems, alcohol or drug abuse, eye problems, low sodium levels, diabetes, serotonin syndrome, and fits. SERTRALINE+ALPRAZOLAM may cause suicidal thoughts and worsen depression or anxiety. So, it should be used with caution in patients with a history of suicidal tendencies and depression.

Drug Interactions

Drug-Drug Interactions: SERTRALINE+ALPRAZOLAM should not be used concomitantly with monoamine oxidase inhibitor (MAOI) (isocarboxazid, phenelzine, selegiline, and moclobemide), MAOI like a drug (linezolid), a medicine used to treat psychosis (pimozide), opioid pain killers (morphine, codeine, and propoxyphene), antifungal drug (ketoconazole), oral contraceptives, antibiotics (erythromycin), a medicine used to treat stomach ulcer (cimetidine), a medicine used to treat high blood pressure and chest pain (diltiazem), a medicine used to treat heart disease (digoxin), and medicine used to treat HIV (ritonavir).

Drug-Food Interactions: Do not consume alcohol as it may cause excessive drowsiness.  

Drug-Disease Interactions: SERTRALINE+ALPRAZOLAM should not be used in patients with severe liver problems, severe breathing problems, and myasthenia gravis (a muscle disorder).

Drug-Drug Interactions Checker List:

  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • MOCLOBEMIDE
  • LINEZOLID
  • PIMOZIDE
  • MORPHINE
  • CODEINE
  • PROPOXYPHENE
  • KETOCONAZOLE
  • ERYTHROMYCIN
  • CIMETIDINE
  • DILTIAZEM
  • DIGOXIN
  • RITONAVIR
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      SERTRALINE+ALPRAZOLAM interacts with alcohol and increases the risk of side-effects such as drowsiness and dizziness.

    • Safety Warning

      Pregnancy

      unsafe

      SERTRALINE+ALPRAZOLAM is a category C medicine. It may cause harmful effects to the unborn baby when used in pregnant women.

    • Safety Warning

      Breast Feeding

      unsafe

      SERTRALINE+ALPRAZOLAM may pass into breastmilk and may cause harmful effects to the nursing baby when used in breastfeeding mothers.

    • Safety Warning

      Driving

      unsafe

      SERTRALINE+ALPRAZOLAM may cause drowsiness and dizziness. So, it is recommended to avoid driving or operating heavy machinery if you are not fully alert.

    • Safety Warning

      Liver

      caution

      SERTRALINE+ALPRAZOLAM should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      SERTRALINE+ALPRAZOLAM should be used with caution in patients with kidney problems. The dose may have to be adjusted by your doctor as required.

    • Safety Warning

      Children

      unsafe

      SERTRALINE+ALPRAZOLAM is not recommended for use in children as the safety and efficacy have not been established.

    Habit Forming

    Yes

    Diet & Lifestyle Advise

    • Eat a well-balanced diet.
    • Avoid processed or packed foods and foods that are high in refined sugars.
    • Exercise regularly.
    • Lose excess weight and keep a check on your weight.
    • Avoid stress.
    • Improve your mood by being active, socializing with others, and talking about your feelings.
    • Quit alcohol intake and smoking.

    Special Advise

    • Do not stop the treatment abruptly as it can cause withdrawal reactions such as stomach cramps, muscle cramps, hallucinations (seeing or hearing things that are not real), and tremors, etc.
    • SERTRALINE+ALPRAZOLAM can be habit-forming. So, do not use it for a duration more than as intended by the doctor. 

    Patients Concern

    Disease/Condition Glossary

    Panic disorder: Panic disorder is a type of anxiety disorder. It is characterized by sudden panic attacks in which patients experience intense fear even if there is no real danger. During a panic attack, you get a rush of intense mental and physical symptoms. It can come on very quickly and for no apparent reason. A panic attack can be very frightening and distressing.

    FAQs

    How does SERTRALINE+ALPRAZOLAM work?

    SERTRALINE+ALPRAZOLAM contains Alprazolam and Sertraline. Alprazolam is a benzodiazepine. It works by increasing the activity of a chemical messenger in the brain that produces a calming-effect. On the other hand, Sertraline is a selective serotonin reuptake inhibitor (SSRI), which increases the release of the serotonin hormone in the body that is responsible for improving mood, cognition and memory.

    Does SERTRALINE+ALPRAZOLAM cause drowsiness?

    SERTRALINE+ALPRAZOLAM may cause drowsiness, so refrain from activities that require you to stay alert such as driving or operating heavy machinery.

    Does SERTRALINE+ALPRAZOLAM treat depression?

    SERTRALINE+ALPRAZOLAM may also treat depression. However, please consult your doctor before taking this medicine for any indication.

    Does SERTRALINE+ALPRAZOLAM cause erectile dysfunction?

    SERTRALINE+ALPRAZOLAM may cause erectile dysfunction in some patients. In general, this condition improves as the body adjusts to the medicine along the course of therapy. However, consult your doctor if the condition persists.

    Is SERTRALINE+ALPRAZOLAM safe in diabetics?

    SERTRALINE+ALPRAZOLAM may affect blood sugar levels. So, let your doctor know that you have diabetes before using SERTRALINE+ALPRAZOLAM.

    Can SERTRALINE+ALPRAZOLAM be used along with antidepressants?

    SERTRALINE+ALPRAZOLAM should not be used along with antidepressants such as monoamine oxidase inhibitors (MAOI). You should wait for at least 14 days before taking SERTRALINE+ALPRAZOLAM after stopping MAOI. So, it is necessary to let your doctor know about all the medicines you are taking before using SERTRALINE+ALPRAZOLAM.

    Available Medicines for

    SERTRALINE+ALPRAZOLAM