Cefoperazone+sulbactam
About Cefoperazone+sulbactam
Sulbactam+cefoperazone is a combination medicine used to treat various bacterial infections such as respiratory tract (lungs) infection, urinary infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.
Sulbactam+cefoperazone contains Cefoperazone and Sulbactam, which work together to treat bacterial infections. It helps control the spread of infection and lowers symptoms. This supports quicker healing and reduces the risk of complications. Together, Sulbactam+cefoperazone helps the body recover from bacterial infections effectively.
Your doctor administers Sulbactam+cefoperazone. You may experience nausea, vomiting, diarrhoea and rash. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.
Inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Consult your doctor before taking Sulbactam+cefoperazone if you are pregnant or planning a pregnancy. Avoid taking Sulbactam+cefoperazone if you are breastfeeding, as Sulbactam+cefoperazone may pass into breast milk.
Uses of Cefoperazone+sulbactam
• Treatment of Bacterial Infections: Sulbactam+cefoperazone is effective against a wide range of bacterial infections, including those affecting the respiratory tract, urinary tract, skin, and soft tissues.
• Management of Intra-Abdominal Infections: Sulbactam+cefoperazone is used to treat severe intra-abdominal infections, such as peritonitis and abscesses.
• Septicemia Treatment: Sulbactam+cefoperazone is prescribed for managing septicemia, a life-threatening condition caused by harmful bacteria in the bloodstream.
• Bone and Joint Infections: Sulbactam+cefoperazone is also used in treating severe infections of bones and joints, such as osteomyelitis and septic arthritis.
Medicinal Benefits
- Helps treat infections affecting the lungs, urine, blood, skin, abdomen, bones, and joints.
- Management of serious infections such as meningitis (infection of the brain and spinal cord) and gonorrhoea (sexually transmitted infection).
- Helps kill harmful bacteria and limits their growth.
- Reduces symptoms such as fever, pain, swelling, and discomfort.
- Helps prevent the infection from spreading to other body parts.
Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication to improve effectiveness.
- Sulbactam+cefoperazone will be administered by a healthcare professional.
- Do not self-administer it.
Storage
Side Effects of Cefoperazone+sulbactam
- Nausea
- Vomiting
- Diarrhoea
- Rash
Medicines Containing this Salt
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Drug Warnings
- Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.
- Do not take Sulbactam+cefoperazone if you have an allergy to Sulbactam+cefoperazone, cephalosporins, or the penicillin class of antibiotics, as it may cause a skin rash, itching, and difficulty in breathing.
- After taking Sulbactam+cefoperazone, if you have allergy-like symptoms, including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor.
- Do not take Sulbactam+cefoperazone if you have an allergy to Sulbactam+cefoperazone, cephalosporins, or the penicillin class of antibiotics, as it may cause a skin rash, itching, and difficulty in breathing.
- People having liver disease or jaundice (yellowing of skin/eye) should not take Sulbactam+cefoperazone, as it can damage their liver severely.
- You may experience diarrhoea, which can be managed by taking probiotics and maintaining adequate hydration.
- Do not take antacids with Sulbactam+cefoperazone; maintain a 2-3-hour interval between them.
- Avoid alcohol consumption while taking Sulbactam+cefoperazone to prevent unpleasant side effects.
- Sulbactam+cefoperazone may cause dizziness; exercise caution when driving.
Drug Interactions
Drug-Drug Interaction: Inform your doctor if you are taking any other medicines, as there may be an interaction.
- Diuretic (water pill) (Furosemide)
• Potential effect: May increase the risk of kidney-related side effects and electrolyte imbalance. - Blood-thinners (Warfarin)
• Potential effect: May enhance the blood-thinning effect and increase the risk of bleeding. - Antibiotics (Amikacin, Gentamicin)
• Potential effect: May increase the risk of kidney toxicity when used together.
Drug-Food Interactions:
Alcohol: Avoid alcohol during treatment with Sulbactam+cefoperazone and for up to 5 days after stopping it, as alcohol may cause flushing, sweating, headache, rapid heartbeat, and other uncomfortable reactions.
Drug-disease interactions: Inform your doctor if you are suffering from any of these conditions.
Colitis (inflammation in the lining of the colon)
Seizures (fits)
Dialysis (blood cleaning treatment)
Kidney problems
Liver problems
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid the intake of alcohol while on treatment with Sulbactam+cefoperazone, as it may increase side effects.
Pregnancy
cautionPlease consult your doctor if you are pregnant, your doctor will prescribe Sulbactam+cefoperazone only if the benefits outweigh the risks.
Breast Feeding
cautionSulbactam+cefoperazone should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.
Driving
cautionSulbactam+cefoperazone may cause dizziness in some people, so it may affect your ability to drive.
Liver
cautionDose adjustment may be needed. Please consult your doctor before taking Sulbactam+cefoperazone if you have liver impairment/liver disease.
Kidney
cautionDose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Sulbactam+cefoperazone.
Children
safe if prescribedSulbactam+cefoperazone should be given to children only when prescribed by a doctor. The doctor decides the right dose for a child based on his/her age and weight.
Habit Forming
Diet & Lifestyle Advise
Gut Health:
- Take probiotic foods after completing the antibiotic course to restore healthy gut bacteria.
- Include fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi.
- Probiotics reduce the risk of diarrhoea after antibiotic use.
Diet:
- Eat fibre-rich foods to support digestion and gut balance.
- Include whole grains such as whole-grain bread and brown rice.
- Include fruits and vegetables to support overall nutrition.
Hydration:
- Drink plenty of water to prevent dehydration.
- Fluids support the body during recovery from infection.
Habits:
- Avoid alcohol as it can interfere with recovery.
- Get enough rest to help the body fight infection.
Special Advise
- Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
- Discontinue Sulbactam+cefoperazone and inform your doctor immediately if you get a rash, itchy skin, swelling of the face and mouth, or have difficulty breathing.
- Diarrhoea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
- Sulbactam+cefoperazone is preferably taken with food to avoid an upset stomach.
- Some people may be allergic to Sulbactam+cefoperazone or other penicillin or cephalosporin group of antibiotics. So a prior sensitivity test may be necessary. Inform your doctor if you are allergic to any medicine, particularly antibiotics that belong to these groups.
- If you feel nauseous after taking Sulbactam+cefoperazone, stick to simple meals like porridge, khichdi, dal roti, and other home-cooked meals. Avoid spicy and fatty food.
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalised symptoms, like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod-shaped, and spiral-shaped. Bacterial infections range from minor illnesses such as sore throat and ear infections to severe brain infections such as meningitis and encephalitis. Anyone can become infected with bacteria. However, individuals with weakened immune systems or those taking immunosuppressive medications are at increased risk of bacterial infections.
FAQs
Sulbactam+cefoperazone is used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections.
No, do not stop receiving Sulbactam+cefoperazone before completing the full course of treatment. You may begin to feel better before the infection is fully resolved. But, it is important to take this medicine for the full duration advised by your doctor.
Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your physician if the symptoms worsen while using this medication.
Usually, Sulbactam+cefoperazone starts working soon after taking it. Though it may take a few days to kill all the dangerous bacteria and make you feel better.
Sulbactam+cefoperazone may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora, leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, consult your doctor. Do not take anti-diarrheal medicine on your own.
Yes, Sulbactam+cefoperazone is known to cause stomach upset. To avoid these side effects, please take Sulbactam+cefoperazone with a meal. Additionally, Sulbactam+cefoperazone should be administered at evenly spaced intervals to minimise adverse effects and optimise outcomes.
It's generally not recommended to consume alcohol while taking Sulbactam+cefoperazone, as it can increase gastrointestinal issues, enhance sedative effects, and interfere with the antibiotic's effectiveness. Consult your doctor for personalised advice.
Sulbactam+cefoperazone is a combination antibiotic medication used to treat various bacterial infections.
Sulbactam+cefoperazone typically begins to work within 1-2 hours after administration, but it may take 2-5 days to notice a significant improvement in symptoms. The full effect of the treatment may be observed after completion of the full course of antibiotics, typically 7-14 days.
Be patient, as it may take time for the infection to clear. If your symptoms don't improve or worsen over time, consult your doctor for further guidance.
Common side effects of Sulbactam+cefoperazone include nausea, vomiting, diarrhoea and rash. Most of these side effects are transient and resolve spontaneously. However, if they persist, it's essential to consult your doctor for proper evaluation and guidance.
