Tazarotene
About Tazarotene
Tazarotene is a prescription topical cream or gel primarily used to treat plaque psoriasis and acne. Its medical purpose is to target abnormal skin cell growth, helping to clear skin lesions and reduce active acne breakouts. This medication provides a direct, localised approach to managing persistent skin irritation and scaling.
Using Tazarotene consistently at the same time each day as directed by your doctor is essential to achieving the best results. Because this is a topical treatment applied directly to the skin, it does not need to be coordinated with food or meals. Supporting your treatment with simple lifestyle changes, such as eating a balanced diet and protecting your skin from the sun, can significantly improve your results.
While using this product, you may experience mild skin peeling, redness, dryness, or a warm, burning sensation where the medicine is applied. These effects are usually temporary as your skin adjusts to the treatment. However, you must contact your doctor immediately if you experience severe skin irritation, deep cracking, bleeding, or signs of an allergic reaction.
Before starting your treatment, tell your doctor if you have eczema, highly sensitive skin, or an active sunburn. Do not use this medicine if you are pregnant, planning to become pregnant, or breastfeeding, as it can cause serious harm to an unborn baby.
Avoid using other drying skin products, such as alcohol-based cosmetics or abrasive cleansers, because they can cause severe irritation when combined with Tazarotene. If you are elderly or have other chronic health conditions, consult your doctor to ensure this topical treatment is safe for you.
Uses of Tazarotene
Medicinal Benefits
Using Tazarotene offers targeted, real-world relief for chronic skin conditions, helping you feel more comfortable in your skin. Some of the key benefits include:
- By regulating skin cell growth, it helps thin down thick, rough plaques and prevents new acne blemishes from forming.
- It significantly calms the intense itching, dry scaling, and painful skin tightness associated with psoriasis.
- Since it is applied directly to the skin, it works precisely where you need it most, minimising systemic side effects.
Directions for Use
- Tazarotene is for external use only.
- It is usually applied once daily at bedtime or as directed by your doctor.
- Check the label for directions before using this medicine.
- Clean and dry the affected area of the skin. Take a small pearl-sized amount of Tazarotene on the fingertip and apply it to the affected area.
- Wash your hands before and after applying Tazarotene.
- If Tazarotene accidentally comes into contact with the nose, mouth, eyes, or vagina, rinse with water thoroughly.
Storage
Side Effects of Tazarotene
Common Side Effects (Usually mild):
- Skin peeling, flaking, or shedding
- Dry skin, mild itching, or redness
- A warm, tingling, or burning sensation at the application site
- Increased sensitivity to sunlight
Serious Side Effects (Call a doctor right away):
- Severe burning, swelling, blistering, or deep cracking of the skin
- Skin bleeding or severe pain in treated areas
- Signs of a severe allergic reaction, such as a widespread rash, hives, or swelling of your face, lips, tongue, or throat
Medicines Containing this Salt
View AllDrug Warnings
- Ensure skin is completely dry: Wait at least 20 to 30 minutes after washing your face before applying Tazarotene, as applying it to damp skin can cause severe irritation.
- Inspect the container: Do not use the gel or cream if the tube is punctured, damaged, or if the product looks discoloured or separated.
- Protect sensitive areas: Keep the cream or gel away from your eyelids, lips, nostrils, and any open wounds, cuts, or eczema patches.
- Avoid harsh hair removal: Do not use wax or chemical hair removers on skin areas treated with Tazarotene, as this can lead to severe skin peeling or damage.
- Shield skin from extreme weather: Cold temperatures and strong winds can make treated skin more prone to severe dryness and windburn; protect your skin with physical barriers like scarves when needed.
Drug Interactions
- Photosensitising medications (e.g., tetracyclines, thiazides, fluoroquinolone antibiotics): Taking oral medicines that increase sun sensitivity can significantly increase your risk of severe sunburn while using Tazarotene.
- Peeling or drying agents (e.g., benzoyl peroxide, salicylic acid, sulfur, resorcinol): Using other topical skin treatments at the same time can cause extreme dryness, peeling, and skin inflammation.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionThe interaction of alcohol with Tazarotene is unknown. Please consult a doctor before consuming alcohol while using Tazarotene.
Pregnancy
unsafeTazarotene should not be used in pregnant women as it may cause harmful effects to the unborn baby or fetus and causes birth defects. Consult your doctor for further advice.
Breast Feeding
unsafeTazarotene may not safe during breastfeeding as it may harm the nursing baby. Consult your doctor for further advice.
Driving
cautionTazarotene has an unknown effect on the ability to drive or use machinery. So, it is better to avoid driving while using Tazarotene.
Liver
cautionTake Tazarotene with caution, especially if you have a history of Liver diseases/conditions as it may cause side effects. The dose may be adjusted by your doctor as required.
Kidney
safe if prescribedTazarotene is not harmful to kidney disease. Tazarotene is safely given to kidney patients if prescribed by your doctor.
Children
unsafeTazarotene is not recommended for children below 18 years of age.
Habit Forming
Diet & Lifestyle Advise
- Protect your skin from the sun: Tazarotene makes your skin highly sensitive to sunburn. Always wear a broad-spectrum sunscreen with SPF 30 or higher during the day, and wear protective clothing when outdoors.
- Avoid harsh skincare products: Stay away from exfoliating scrubs, astringents, or products containing alcohol, spices, or lime, which can strip your skin and worsen irritation.
- Keep skin hydrated: Use a gentle, fragrance-free moisturiser daily to manage skin peeling and dryness, keeping your skin's barrier healthy.
- Avoid hot water: Wash treated areas with lukewarm water instead of hot water, as hot water can deplete natural oils and increase skin sensitivity.
Special Advise
Do not cover the area being treated with airtight dressings like bandages unless ordered by a doctor, as this may enhance the risk of side effects.
Patients Concern
Disease/Condition Glossary
Psoriasis: Psoriasis is an autoimmune skin disease characterized by red, itchy and scaly rashes. It occurs when the immune system mistakenly attacks healthy skin cells. In this condition, skin cells grow and build up rapidly resulting in scaly rashes mostly on knees, elbows, scalp and trunk. Stress and cold can act as triggers for this disease. It is a chronic disease and does not have a permanent cure. Treatment is given to control the disease and prevent flare-ups.
Acne: Acne is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, and red, large, and tender bumps.
FAQs
No. Tazarotene contains tazarotene, which can cause serious harm to an unborn baby and must not be used during pregnancy. If you are pregnant, planning to become pregnant, or think you may be pregnant, stop using the medicine and contact your doctor immediately to discuss alternative treatment options.
Yes. You can apply cosmetics or makeup while using Tazarotene, but allow the medicine to dry and absorb completely before applying other products. Choose gentle, oil-free, non-comedogenic cosmetics to reduce the risk of skin irritation or clogged pores. If your skin becomes irritated, speak with your doctor.
Some formulations of tazarotene are prescribed to improve the appearance of fine wrinkles, uneven skin pigmentation, and sun-damaged skin. However, not all Tazarotene products are intended for cosmetic use. Use the medicine only for the condition your doctor has prescribed, and ask your doctor whether it is appropriate for anti-ageing treatment.
Mild peeling is common when starting Tazarotene. You can manage this by using a gentle, fragrance-free moisturiser or asking your doctor about applying the medicine less frequently. If the peeling becomes painful or severe, talk to your doctor.
Yes, but chlorine and pool water can dry out your skin, making it more sensitive to irritation from Tazarotene. Wash your skin gently with clean water after swimming and apply a gentle moisturiser. If your skin remains highly irritated, talk to your doctor.
No, applying Tazarotene more often will not speed up your recovery and is highly likely to cause severe redness, peeling, and skin pain. Always use the medicine exactly as directed, and if you feel your treatment is not working, talk to your doctor.
Because Tazarotene is a topical skin treatment, there are no specific foods or beverages you need to avoid. However, a healthy, balanced diet is always beneficial for your skin. For any concerns regarding diet and skin health, talk to your doctor.

