Ceftriaxone+tazobactam
About Ceftriaxone+tazobactam
Tazobactam+ceftriaxone belongs to a class of medication called 'antibiotics' used to treat several bacterial infections of the urinary tract, blood, bones and joints, heart, brain, chest, ears, skin, or soft tissues. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Tazobactam+ceftriaxone does not work against infections caused by the virus.
Tazobactam+ceftriaxone is a combination of two drugs: Ceftriaxone (antibiotic) and Tazobactum (beta-lactamase inhibitor). Ceftriaxone belongs to the class of antibiotics that works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.
You are advised to take Tazobactam+ceftriaxone for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, rash, or abnormalities with white blood cells and platelets. Most of these side effects of Tazobactam+ceftriaxone do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Tazobactam+ceftriaxone, penicillins, or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Tazobactam+ceftriaxone. Drive only if you are alert as Tazobactam+ceftriaxone may cause dizziness. You are recommended to complete the full course of Tazobactam+ceftriaxone as prescribed by your doctor for effective results. Tazobactam+ceftriaxone may interact with certain tests such as glucose (sugar) in urine and coomb’s test, giving unusual results. Therefore, inform the doctor that you are taking Tazobactam+ceftriaxone before undergoing any tests.
Uses of Ceftriaxone+tazobactam
• Treatment of Bacterial Infections: Tazobactam+ceftriaxone is commonly prescribed to manage bacterial infections, including those targeting the respiratory tract, urinary tract, and skin, ensuring effective treatment.
• Post-Surgical Infection Prevention: Tazobactam+ceftriaxone may be administered to reduce the risk of infections in patients undergoing surgery, particularly during high-risk procedures.
• Management of Sepsis: Tazobactam+ceftriaxone is used as part of the treatment regimen for sepsis, a life-threatening condition caused by infection.
• Pneumonia Treatment: Tazobactam+ceftriaxone is effective in treating pneumonia, especially when caused by bacterial pathogens sensitive to its active components.
• Typhoid Fever Management: Tazobactam+ceftriaxone may be prescribed for typhoid fever, particularly in situations where oral medications are unsuitable or ineffective.
Medicinal Benefits
Tazobactam+ceftriaxone is a combination of two drugs: Ceftriaxone (antibiotic) and Tazobactum (beta-lactamase inhibitor) used to treat several bacterial infections. Ceftriaxone is a broad-spectrum antibiotic that acts against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.
Directions for Use
- Follow your doctor's instructions on the dosage and timing of this medication.
- Tazobactam+ceftriaxone will be administered by the doctor or nurse in a healthcare setting.
- Do not self-administer.
Storage
Side Effects of Ceftriaxone+tazobactam
Diarrhoea
Rash
Raised white blood cells
Raised platelets
Nausea
Vomiting
Upset stomach
Blood clots
Dizziness
headache
a lump where the medicine was injected,
Sweating
Medicines Containing this Salt
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Drug Warnings
If you are allergic to Tazobactam+ceftriaxone, penicillins, or any other medicines, please tell your doctor. If you have kidney or liver problems, diarrhea, hemolytic anemia (reduction in red blood cells that may make your skin pale yellow and cause breathlessness or weakness), kidney or gall stones, or inflammation of the large intestine, inform your doctor before taking Tazobactam+ceftriaxone. If you are pregnant or breastfeeding, please inform your doctor before taking Tazobactam+ceftriaxone. Drive only if you are alert as Tazobactam+ceftriaxone may cause dizziness. You are recommended to complete the full course of Tazobactam+ceftriaxone as prescribed by your doctor for effective results. Tazobactam+ceftriaxone may interact with certain tests such as glucose (sugar) in urine and coomb’s test, giving unusual results. Therefore, inform the doctor that you are taking Tazobactam+ceftriaxone before undergoing any tests. If you are on a low-sodium diet or are about to receive calcium-containing products, please inform your doctor before taking Tazobactam+ceftriaxone.
Drug Interactions
Drug-Drug Interaction: Tazobactam+ceftriaxone may interact with a blood thinner (heparin), drugs used to lower high uric acid levels (probenecid), neuromuscular blocking agent (vecuronium), anticancer drug (methotrexate), water tablet (furosemide) and antibiotics (chloramphenicol, gentamicin, streptomycin).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have kidney or liver problems, diarrhea, hemolytic anemia (reduction in red blood cells that may cause breathlessness or weakness and make your skin pale yellow), kidney or gall stones, inflammation of the large intestine, inform your doctor before taking Tazobactam+ceftriaxone.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionInteraction of Tazobactam+ceftriaxone with alcohol is unknown. Please consult a doctor before consuming alcohol while using Tazobactam+ceftriaxone.
Pregnancy
cautionPlease consult a doctor if you are pregnant or planning for pregnancy. Tazobactam+ceftriaxone is given to pregnant women only if the doctor thinks benefits outweigh risks.
Breast Feeding
cautionIt is unknown whether Tazobactam+ceftriaxone is excreted in human milk. Tazobactam+ceftriaxone is given to breastfeeding mothers if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.
Driving
cautionTazobactam+ceftriaxone may cause dizziness in some people. Therefore, avoid driving if you feel dizzy after taking Tazobactam+ceftriaxone.
Liver
cautionTake Tazobactam+ceftriaxone with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Tazobactam+ceftriaxone with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
cautionTazobactam+ceftriaxone is not recommended for premature and new-born babies up to 28 days who has jaundice or certain blood problems. However, Tazobactam+ceftriaxone is given to children only if prescribed by a doctor.
Habit Forming
Diet & Lifestyle Advise
Take probiotics after completing the full course of Tazobactam+ceftriaxone to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can help to restore the good bacteria of the intestine.
Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
Make sure you drink plenty of water or other fluids every day while you are taking Tazobactam+ceftriaxone.
Avoid alcohol consumption as it may increase adverse effects.
Special Advise
Regular blood tests are recommended if you take Tazobactam+ceftriaxone for a long time to monitor changes in white blood cells, platelets, and liver functioning.
If you are about to undergo any blood or urine tests, inform your doctor that you are taking Tazobactam+ceftriaxone as it may interfere with urine the est (for sugar) and Coomb’s test results.
Patients Concern
Disease/Condition Glossary
Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes, namely spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.
FAQs
Tazobactam+ceftriaxone is used to treat bacterial infections of the urinary tract, blood, bones and joints, heart, brain, chest, ears, skin, or soft tissues.
Tazobactam+ceftriaxone contains Ceftriaxone and Tazobactum. Ceftriaxone is an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria. Tazobactum is a beta-lactamase inhibitor that enhances the activity of ceftriaxone and decreases resistance.
Tazobactam+ceftriaxone may interfere with urine test (for sugar) and Coomb’s test (blood test) giving false-positive results. Therefore, if you are about to undergo any laboratory tests, inform your doctor or lab technician that you are taking Tazobactam+ceftriaxone.
You are not recommended to take Tazobactam+ceftriaxone with streptomycin as co-administration of these two medicines may increase the risk of kidney damage. However, please consult your doctor before taking Tazobactam+ceftriaxone with other medicines to adjust the dose appropriately.
Tazobactam+ceftriaxone may cause diarrhoea as a common side effect. However, if the condition persists, worsens or notices blood or mucus in stools, avoid taking Tazobactam+ceftriaxone and consult a doctor immediately.
Tazobactam+ceftriaxone is not used to treat viral infections. Tazobactam+ceftriaxone is an antibiotic which is used to treat only bacterial infections.
Tazobactam+ceftriaxone should be used with caution in patients with kidney problems as it may increase the risk of adverse effects. Therefore, inform your doctor if you have any kidney problems before taking Tazobactam+ceftriaxone so that the dose may be adjusted accordingly.
Generally, Tazobactam+ceftriaxone starts working soon after taking it, as it is injected directly into the blood stream. However to kill all the harmful bacteria and make you feel better, it may take some days. So, complete the full course of treatment as prescribed by your doctor.
Inform your doctor if you don't get better after finishing the full course of treatment as prescribed by your doctor. Also, inform if your symptoms are getting worse while using Tazobactam+ceftriaxone.
The common side effects of Tazobactam+ceftriaxone are diarrhoea, rash, raised white blood cells, raised platelets, nausea, vomiting, stomach upset, blood clots, dizziness, headache, a lump where the medicine was injected and sweating. If any of these side effects persist or worsen, please consult your doctor.
