Apomorphine

Apomorphine is an injectable prescription medicine used to treat sudden, temporary loss of movement control, often called 'off' episodes, in people with advanced Parkinson's disease. These episodes cause severe muscle stiffness, slow movement, or an inability to move at all. This medicine helps restore movement during these sudden freezing periods so you can carry out your daily activities.

You should inject Apomorphine only when you begin to experience an 'off' episode, up to the maximum daily limit recommended by your doctor. Because it is injected under the skin, its absorption is not affected by food, but staying well-hydrated is important to help prevent dizziness. Combining this treatment with regular physical therapy and a balanced diet can help improve your overall mobility and coordination.

While using this medicine, you may experience mild side effects like nausea, yawning, or redness at the injection site. However, you must contact your doctor immediately if you experience serious symptoms such as severe dizziness, fainting, confusion, or unusual hallucinations. Your healthcare team can help adjust your plan to manage these symptoms safely.

Before starting Apomorphine, tell your doctor if you have a history of heart problems, low blood pressure, liver damage, or kidney disease. Do not take this medicine if you have a known allergy to sulphites, as this product contains ingredients that can trigger severe allergic reactions in sensitive individuals. Your doctor will carefully review your medical history to ensure this treatment is safe for you.

This injection can interact with alcohol and certain medicines, especially blood pressure drugs and specific anti-nausea medicines, which can cause dangerously low blood pressure. If you are pregnant, breastfeeding, or planning a pregnancy, or if you are an older adult, talk to your doctor or pharmacist to discuss the risks and benefits of using this medicine.
 

Apomorphine provides rapid support for sudden movement difficulties and helps improve physical independence during Parkinson's disease 'off' episodes. The key benefits of Apomorphine include:

• Rapid Relief from Sudden Immobility: Apomorphine provides rapid relief from sudden immobility, usually starting to work within minutes of injection. This fast action helps you regain control over your movements quickly, allowing you to return to your normal routine without prolonged waiting periods.
• Improved Physical Independence: By effectively reversing 'off' episodes, this medicine helps reduce the anxiety and frustration associated with sudden freezing. It supports greater physical independence, making it easier to perform everyday tasks like walking, eating, and dressing without relying constantly on assistance.
   

• Follow your doctor’s instructions on the dosage and timing of this medication.
• Apomorphine is typically given by a healthcare provider or self-administered with proper training.
• It is administered subcutaneously (under the skin).

Common Side Effects (Usually mild):

• Nausea and vomiting
• Sleepiness, yawning, or sudden drowsiness
• Redness, swelling, bruising, or pain at the injection site
• Dizziness or lightheadedness when standing up

Serious Side Effects (Consult your doctor right away):

• Fainting or severe loss of balance
• Hallucinations, confusion, or unusual changes in behaviour
• Intense, uncontrollable urges (such as gambling, spending, or sexual urges)
• A painful erection that lasts longer than four hours
• Chest pain, shortness of breath, or a fast, pounding heartbeat
• Severe allergic reactions, including hives, swelling of the face or throat, and difficulty breathing